Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caroline Hojer"'
Autor:
Steinar Halldórsson, Lars Hillringhaus, Caroline Hojer, Andrea Muranyi, Michael Schraeml, Magdalena Swiatek-de Lange, Gloria Tabarés
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prostate-specific antigen (PSA) levels are widely used to screen for prostate cancer, yet the test has poor sensitivity, specificity and predictive value, which leads to overdiagnosis and overtreatment. Alterations in the glycosylation statu
Externí odkaz:
https://doaj.org/article/ef98887a925b43faa0aac0379ac42831
Autor:
Winther, Camille Caroline Højer, Klein-Petersen, Amalie Wandel, Preel, Marie, Kofoed, Inge Ring, Bo Nissen, Ida, Axelgaard, Sofie, Green, Julie, Miranda, Maria J, Hoei-Hansen, Christina Engel
Publikováno v:
In Seizure: European Journal of Epilepsy August 2024 120:173-179
Autor:
Ursula Zimber-Strobl, Klaus Rajewsky, Jürgen Ruland, Uta Ferch, Cornelia Hömig-Hölzel, Franziska Jagdhuber, Kristina Djermanovic, Samantha Feicht, Lothar J. Strobl, Samantha Frankenberger, Caroline Hojer
CD40, a member of the TNF receptor family, is expressed on all mature B cells and on most B-cell lymphomas. Recently, we have shown that constitutive activation of CD40 signaling in B cells induced by a fusion protein consisting of the transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cedc181c40859c7fe351b35354dc84b3
https://doi.org/10.1158/0008-5472.c.6505752
https://doi.org/10.1158/0008-5472.c.6505752
Autor:
Ursula Zimber-Strobl, Klaus Rajewsky, Jürgen Ruland, Uta Ferch, Cornelia Hömig-Hölzel, Franziska Jagdhuber, Kristina Djermanovic, Samantha Feicht, Lothar J. Strobl, Samantha Frankenberger, Caroline Hojer
PDF file - 364K, Suppl. Figure 1. BM B cell development is comparable in LMP1/CD40//CD19+/- and LMP1/CD40//CD19-/- mice. Suppl. Figure 2. CD40 employs CD19 to mediate survival signals. Suppl. Figure 3. Loss of CD19 abrogates lymphoma development in L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f70703ca0025303d553d01f31e2d2a6
https://doi.org/10.1158/0008-5472.22401078.v1
https://doi.org/10.1158/0008-5472.22401078.v1
B-cell Expansion and Lymphomagenesis Induced by Chronic CD40 Signaling Is Strictly Dependent on CD19
Autor:
Caroline Hojer, Samantha Feicht, Lothar J. Strobl, Ursula Zimber-Strobl, Samantha Frankenberger, Franziska Jagdhuber, Klaus Rajewsky, Kristina Djermanovic, Jürgen Ruland, Cornelia Hömig-Hölzel, Uta Ferch
Publikováno v:
Cancer Res. 74, 4318-4328 (2014)
CD40, a member of the TNF receptor family, is expressed on all mature B cells and on most B-cell lymphomas. Recently, we have shown that constitutive activation of CD40 signaling in B cells induced by a fusion protein consisting of the transmembrane
Autor:
Ralf Kühn, Marc Schmidt-Supprian, Lothar J. Strobl, Franziska Hampel, Gabriele Marschall-Schröter, Stefanie Ehrenberg, Caroline Hojer, Anne Draeseke, Brigitte Mack, Christoph J. Vahl, Ursula Zimber-Strobl, Olivier Gires
Publikováno v:
Blood. 118:6321-6331
B cell–specific gene ablation of Notch2 results in the loss of the marginal zone (MZ) B-cell lineage. To analyze the effects of constitutive Notch2 signaling in B cells, we have generated a transgenic mouse strain that allows the conditional expres
Autor:
Julia Rastelli, Stefano Casola, Klaus Rajewsky, Werner Müller, Leticia Quintanilla-Martinez, Jürgen Ruland, Ursula Zimber-Strobl, Caroline Hojer, Cornelia Hömig-Hölzel, Lothar J. Strobl, Andreas Gewies
Publikováno v:
The Journal of Experimental Medicine
J. Exp. Med. 205, 1317-1329 (2008)
J. Exp. Med. 205, 1317-1329 (2008)
CD40, a member of the tumor necrosis factor (TNF) receptor family, plays an essential role in T cell–dependent immune responses. Because CD40 is widely expressed on the surface of tumor cells in various B cell malignancies, deregulated CD40 signali
Autor:
Brian L. Yaspan, Meijuan Zhou, Wyne P. Lee, Caroline Hojer, Chiao-Wen Yang, Xiumin Wu, Arthur Wuster, Andrew C. Chan
Publikováno v:
Cell. 164(1-2)
The DENN domain is an evolutionary conserved protein module found in all eukaryotes and serves as an exchange factor for Rab-GTPases to regulate diverse cellular functions. Variants in DENND1B are associated with development of childhood asthma and o
Autor:
Christoph P. Mauch, Hans-Ulrich Dodt, Frank Bradke, Klaus Becker, Caroline Hojer, Jackson G. Egen, Nina Jährling, Ali Ertürk, Morgan Sheng, Farida Hellal
Publikováno v:
Nature protocols 7(11), 1983-1995 (2012). doi:10.1038/nprot.2012.119
The examination of tissue histology by light microscopy is a fundamental tool for investigating the structure and function of organs under normal and disease states. Many current techniques for tissue sectioning, imaging and analysis are time-consumi