Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Caroline Heintz"'
Autor:
Carlos G. Silva-García, Anne Lanjuin, Caroline Heintz, Sneha Dutta, Nicole M. Clark, William B. Mair
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2195-2198 (2019)
We have generated a single-copy knock-in loci for defined gene expression (SKI LODGE) system to insert any DNA by CRISPR/Cas9 at defined safe harbors in the Caenorhabditis elegans genome. Utilizing a single crRNA guide, which also acts as a Co-CRISPR
Externí odkaz:
https://doaj.org/article/01b6160a30a14edd9b392a8265bba243
Autor:
Tamara Szentiványi, Anne‐Caroline Heintz, Wanda Markotter, Jérôme Wassef, Philippe Christe, Olivier Glaizot
Publikováno v:
Medical and veterinary entomology, vol. 37, no. 2, pp. 189-194
Bats are known reservoir hosts for a wide variety of parasites and pathogens, including bacteria and protozoans. Some of these pathogens are vector-borne, and although their role is poorly studied, ectoparasites may contribute significantly to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07a633b4a4a3725868d039f81b602b7
https://serval.unil.ch/resource/serval:BIB_375BFEE6C952.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_375BFEE6C952.P001/REF.pdf
Autor:
Laura E. Wester, Anne Lanjuin, Emanuel H.W. Bruckisch, Maria C. Perez-Matos, Peter G. Stine, Caroline Heintz, Martin S. Denzel, William B. Mair
Publikováno v:
Cell Rep Methods
Here, we introduce a single-copy knockin translating ribosome immunoprecipitation (SKI TRIP) toolkit, a collection of Caenorhabditis elegans strains engineered by CRISPR in which tissue-specific expression of FLAG-tagged ribosomal subunit protein RPL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64a426d2278e05a3c826cc19af3f87d
https://europepmc.org/articles/PMC10088236/
https://europepmc.org/articles/PMC10088236/
Autor:
Carlos G. Silva-García, Laura I. Láscarez-Lagunas, Katharina Papsdorf, Caroline Heintz, Aditi Prabhakar, Christopher S. Morrow, Lourdes Pajuelo Torres, Arpit Sharma, Jihe Liu, Monica P. Colaiácovo, Anne Brunet, William B. Mair
SUMMARYLoss of function during ageing is accompanied by transcriptional drift, altering gene expression and contributing to a variety of age-related diseases. CREB-regulated transcriptional coactivators (CRTCs) have emerged as key regulators of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8f7b029d930e5b4c10c61849f6461d
https://doi.org/10.1101/2022.08.31.506037
https://doi.org/10.1101/2022.08.31.506037
Autor:
Laura E. Wester, Anne Lanjuin, Emanuel H. W. Bruckisch, Maria C. Perez Matos, Caroline Heintz, Martin S. Denzel, William B. Mair
Translating Ribosome Affinity Purification (TRAP) methods have emerged as a powerful approach to profile actively translated transcripts in specific cell and tissue types. Epitope tagged ribosomal subunits are expressed in defined cell populations an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c989cbf9c30fae1d5b33e92257d4549
https://doi.org/10.1101/2021.12.22.473890
https://doi.org/10.1101/2021.12.22.473890
Autor:
Sehgal R, Perez-Matos Mc, William B. Mair, Hannah J. Smith, Mutlu As, Meeta Mistry, Porsha R. Howell, Anne Lanjuin, Sneha Dutta, Meng C. Wang, Arpit Sharma, Mary E. Piper, Caroline Heintz
Geroscience aims to target the aging process to extend healthspan. However, even isogenic individuals show heterogeneity in natural aging rate and responsiveness to pro-longevity interventions, limiting translational potential. Using in vivo mini gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b91c2b30e545cde54ca5814f2ebef4f
https://doi.org/10.1101/2021.11.01.466772
https://doi.org/10.1101/2021.11.01.466772
Autor:
William B. Mair, Carlos G. Silva-García, Caroline Heintz, Nicole M Clark, Sneha Dutta, Anne Lanjuin
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2195-2198 (2019)
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2195-2198 (2019)
We have generated a single-copy knock-in loci for defined gene expression (SKI LODGE) system to insert any DNA by CRISPR/Cas9 at defined safe harbors in the Caenorhabditis elegans genome. Utilizing a single crRNA guide, which also acts as a Co-CRISPR
Autor:
William B. Mair, Thomas Koed Doktor, Brendan D. Manning, Carlos G. Silva-García, Anne Lanjuin, Sneha Dutta, Yue Zhang, Gitte Hoffmann Bruun, Brage S. Andresen, Heather J. Weir, Caroline Heintz, Ianessa Morantte, Gerta Hoxhaj, Caroline C. Escoubas
Publikováno v:
Nature
Heintz, C, Doktor, T K, Lanjuin, A, Escoubas, C C, Zhang, Y, Weir, H J, Dutta, S, Silva-García, C G, Bruun, G H, Morantte, I, Hoxhaj, G, Manning, B D, Andresen, B S & Mair, W B 2017, ' Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans ', Nature, vol. 541, no. 7635, pp. 102-106 . https://doi.org/10.1038/nature20789
Heintz, C, Doktor, T K, Lanjuin, A, Escoubas, C C, Zhang, Y, Weir, H J, Dutta, S, Silva-García, C G, Bruun, G H, Morantte, I, Hoxhaj, G, Manning, B D, Andresen, B S & Mair, W B 2017, ' Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans ', Nature, vol. 541, no. 7635, pp. 102-106 . https://doi.org/10.1038/nature20789
Ageing is driven by a loss of transcriptional and protein homeostasis and is the key risk factor for multiple chronic diseases. Interventions that attenuate or reverse systemic dysfunction associated with age therefore have the potential to reduce ov
Publikováno v:
Protocol Exchange.
Autor:
Anne Lanjuin, William B. Mair, Brendan D. Manning, Caroline Heintz, Caroline C. Escoubas, Gitte Hoffmann Bruun, Gerta Hoxhaj, Carlos G. Silva-García, Thomas Koed Doktor, Yue Zhang, Ianessa Morantte, Sneha Dutta, Heather J. Weir, Brage S. Andresen
Publikováno v:
Heintz, C, Doktor, T K, Lanjuin, A, Escoubas, C C, Zhang, Y, Weir, H J, Dutta, S, Silva-García, C G, Bruun, G H, Morantte, I, Hoxhaj, G, Manning, B D, Andresen, B S & Mair, W B 2017, ' Correction: Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans ', Nature, vol. 547, no. 7664, pp. 476 . https://doi.org/10.1038/nature23313
Nature 541, 102–106 (2017); doi:10.1038/nature20789 After publication, we noticed errors in the Source Data files for Fig. 2, Extended Data Figs 5, 6 and 9 and Supplementary Fig. 1 of this Letter. These result from data mislabelling, and have no ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83555e39adf9e3fe159274aae908d480
https://portal.findresearcher.sdu.dk/da/publications/8a46cdde-5f19-4538-b380-d05e637ea688
https://portal.findresearcher.sdu.dk/da/publications/8a46cdde-5f19-4538-b380-d05e637ea688