Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice

Autor: Laura Moutard, Caroline Goudin, Catherine Jaeger, Céline Duparc, Estelle Louiset, Tony Pereira, François Fraissinet, Marion Delessard, Justine Saulnier, Aurélie Rives-Feraille, Christelle Delalande, Hervé Lefebvre, Nathalie Rives, Ludovic Dumont, Christine Rondanino

Publikováno v: eLife, Vol 12 (2023)

Children undergoing cancer treatments are at risk for impaired fertility. Cryopreserved prepubertal testicular biopsies could theoretically be later matured in vitro to produce spermatozoa for assisted reproductive technology. A complete in vitro spe

Externí odkaz: https://doaj.org/article/7708908cd703458cb420d7a9aeb4be9b

Estrogen receptor α regulates the expression of syndecan-1 in human breast carcinoma cells

Autor: Vincent Hanoux, Caroline Goudin, Emmanuelle Fleurot, Jérôme Levallet, Pierre-Jacques Bonnamy

Publikováno v: Endocrine-Related Cancer
Endocrine-Related Cancer, BioScientifica, 2019, 26 (6), pp.615-628. ⟨10.1530/ERC-18-0285⟩
Endocrine-Related Cancer, 2019, 26 (6), pp.615-628. ⟨10.1530/ERC-18-0285⟩

Breast cancer (BC) is the primary cause of cancer-related mortality among women. Patients who express the estrogen receptor (ER), which mediates the tumorigenic effects of estrogens, respond to antihormonal therapy. Loss of ER expression or acquired

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabc17fd8b1759b4b1ba3e9a6e14180a
https://hal-normandie-univ.archives-ouvertes.fr/hal-02121052