Zobrazeno 1 - 2
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pro vyhledávání: '"Caroline Gauvin"'
Publikováno v:
Journal of Separation Science. 30:1191-1199
The use of sub-2-microm particle columns for fast high throughput metabolite ID applications was investigated. Three LC-MS methods based on different sub-2-microm particle size columns using the same analytical 3 min gradient were developed (Methods
Autor:
Bettina A. Hamelin, Jacques Turgeon, Gilles O'Hara, Caroline Gauvin, M.A. Yessine, Line Labbé, Etienne Lessard, Jacynthe Leblanc
Publikováno v:
Journal of Clinical Psychopharmacology. 21:175-184
CYP2D6 is the major enzyme involved in the metabolism of venlafaxine. Subjects with a low CYP2D6 activity have increased plasma concentrations of venlafaxine that may predispose them to cardiovascular side effects. In vitro and in vivo studies showed