Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caroline G. L. Lee"'
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-13 (2018)
Abstract Background Genetic polymorphisms can contribute to phenotypic differences amongst individuals, including disease risk and drug response. Characterization of genetic polymorphisms that modulate gene expression and/or protein function may faci
Externí odkaz:
https://doaj.org/article/bab5aea225304226a87a4085c92cf0f9
Publikováno v:
Biology Open, Vol 4, Iss 8, Pp 961-969 (2015)
Pleiotropic pro-inflammatory cytokines, TNF-α and IFN-γ (TI), play important yet diverse roles in cell survival, proliferation, and death. Recent evidence highlights FAT10 as a downstream molecule in the pathway of inflammation-induced tumorigenesi
Externí odkaz:
https://doaj.org/article/98a27a01a02f40e1a31f667a652cb984
Autor:
Yu Jin, Caroline G. L. Lee
Publikováno v:
Biomolecules, Vol 3, Iss 2, Pp 287-302 (2013)
Since the discovery of microRNA (miRNA), the polymorphisms that affect miRNA regulation had been extensively investigated by many independent studies. Recently, researchers utilized bioinformatics and statistical approaches for genome-wide analysis o
Externí odkaz:
https://doaj.org/article/5ad996ab8bd24d5792c94eea8376b24a
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 940 (2016)
Chronic hepatitis B virus (HBV) infection is one of the most associated factors in hepatocarcinogenesis. HBV is able to integrate into the host genome and encode the multi-functional hepatitis B virus x protein (HBx). Although the mechanism between H
Externí odkaz:
https://doaj.org/article/fa475ab9b860423f953c85f9e829aff4
Publikováno v:
Single Nucleotide Polymorphisms ISBN: 9783031056147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947cd43267dbb70adbd4631c9cf20e26
https://doi.org/10.1007/978-3-031-05616-1_8
https://doi.org/10.1007/978-3-031-05616-1_8
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H2319-H2324
Nitric oxide synthases are a family of enzymes capable of converting l-arginine to l-citrulline with the subsequent release of nitric oxide (NO). NO has been shown to have multiple biologic effects depending on the isoform responsible for its product
Publikováno v:
Analytical Biochemistry. 205:36-41
We have developed two methods for selective 5' modification of RNAs generated by enzymatic synthesis using T7 RNA polymerase. The first method involves a two-step procedure. Transcription reactions are performed under standard conditions except that
Publikováno v:
Immunogenetics. 41
The expression of many genes is altered upon the activation of macrophages by bacterial LPS. These genes play a crucial role in the orchestration of various responses to protect the host against infection. A novel 2.3 kilobase (kb) cDNA, designated I
Publikováno v:
Mammalian Genome. 6:56-57
Publikováno v:
Mammalian Genome. 5:742-743