Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caroline G Lucas"'
Autor:
Melissa Samuel, Caroline A Pfeiffer, Destiny N Johns, Matthew C. Lucy, Kevin D. Wells, Melissa A Fudge, Lee D. Spate, Hongyu Liu, Shelbi D Perry, Caroline G Lucas, Paula R Chen, Christine Spinka, Rodney D. Geisert, Thomas E. Spencer, Raissa F. Cecil, Randall S. Prather, Ashley E Meyer
Publikováno v:
Biology of Reproduction. 105:1577-1590
Establishment and maintenance of pregnancy in the pig is a complex process that relies on conceptus regulation of the maternal proinflammatory response to endometrial attachment. Following elongation, pig conceptuses secrete interferon gamma (IFNG) d
Publikováno v:
Molecular Reproduction and Development
Glutamine supplementation to porcine embryo culture medium improves development, increases leucine consumption, and enhances mitochondrial activity. In cancer cells, glutamine has been implicated in the activation of mechanistic target of rapamycin c
Autor:
Rodney D. Geisert, Destiny N. Johns, Caroline A. Pfeiffer, Riley M. Sullivan, Caroline G. Lucas, Constantine A. Simintiras, Bethany K. Redel, Kevin D. Wells, Thomas E. Spencer, Randall S. Prather
Publikováno v:
Molecular Reproduction and Development.
CRISPR-Cas9 gene editing technology provides a method to generate loss-of-function studies to investigate, in vivo, the specific role of specific genes in regulation of reproduction. With proper design and selection of guide RNAs (gRNA) designed to s
Autor:
Paula R Chen, Bethany K. Redel, Lee D. Spate, Randall S. Prather, Caroline G Lucas, Kevin D. Wells
Publikováno v:
Reprod Toxicol
Pigs have become an important model for agricultural and biomedical purposes. The advent of genomic engineering tools, such as the CRISPR/Cas9 system, has facilitated the production of livestock models with desired modifications. However, precise sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5051621f2c98bc055507c629d3005
https://europepmc.org/articles/PMC8511169/
https://europepmc.org/articles/PMC8511169/
Publikováno v:
Mol Reprod Dev
An appropriate environment to optimize porcine preimplantation embryo production in vitro is required as genetically modified pigs have become indispensable for biomedical research and agriculture. To provide suitable culture conditions, omics techno
Autor:
W C Warren, Melissa Samuel, Randall S. Prather, Kevin D. Wells, Anna Spate, Caroline G Lucas, Lee D. Spate
Publikováno v:
Transgenic Res
Advances in genome editing tools have reduced barriers to the creation of animal models. Due to their anatomical and physiological similarities to humans, there has been a growing need for pig models to study human diseases, for xenotransplantation a
Autor:
Antonio Sergio Varela Junior, Carine Dahl Corcine, Mariana Härter Remirão, Willian A. Prado, Tony Silveira, William Borges Domingues, Arthur de Castro Jorge Silva, Silvia Stanisçuaski Guterres, Vinicius Farias Campos, Denise S. Jornada, Fabiana Kömmling Seixas, Caroline G Lucas, Júlia Damé Paschoal, Adriana Raffin Pohlmann, Tiago Collares
Publikováno v:
Toxicology in Vitro. 40:214-222
Toxicology studies have a pivotal role for selection of new nanosystems. As lipid-core nanocapsules (LNC) rise as a potential system not only for drug delivery but also for immunotherapy and gene therapy, the demand for models of toxic screening incr
Autor:
Vinicius Farias Campos, Andrea Cristina Basso, Tiago Collares, Fabiana Kömmling Seixas, Eliza Rossi Komninou, C. S. Haas, Adriana Raffin Pohlmann, Priscila Marques Moura de Leon, Ruy Carlos Ruver Beck, Caroline G Lucas, William Borges Domingues, Mariana H. Remião, Silvia Stanisçuaski Guterres, Aline Ferreira Ourique
Publikováno v:
Reproductive Toxicology. 58:131-139
In vitro oocyte maturation (IVM) protocols can be improved by adding chemical supplements to the culture media. Tretinoin is considered an important retinoid in embryonic development and its association with lipid-core nanocapsules (TTN-LNC) represen
Publikováno v:
Chemico-biological interactions. 285
All-trans retinoic acid (ATRA), a derivative of vitamin A, has been shown to potentiate cancer chemotherapy due to its ability to induce signals for cell differentiation or death, and inhibit cell proliferation. The combination of ATRA with taxoids,
Autor:
Franciele Aline Bruinsmann, Caroline G Lucas, Isadora A.R. Lopes, Mariana H. Remião, Ana Laura da S. Feijó, Andrea Cristina Basso, Fabiana Kömmling Seixas, Tiago Collares, Adriana Raffin Pohlmann, Vinicius Farias Campos, Morgana Alves Borges, Silvia Stanisçuaski Guterres
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 45(Pt 1)
The improvement of in vitro embryo production by culture media supplementation has been a potential tool to increase blastocyst quality and development. Recently, lipid-core nanocapsules (LNC), which were developed for biomedical applications as a dr