Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Caroline F. Samer"'
Autor:
Frédérique Rodieux, Youssef Daali, Victoria Rollason, Caroline F. Samer, Kuntheavy Ing Lorenzini
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Pharmacokinetics varies widely between children. Many factors play an important role in this variability, such as ontogeny, pharmacogenetics, gender, comorbidities, and drug-drug interactions. Significant work has already been done in adults to under
Externí odkaz:
https://doaj.org/article/e183021b6369401a9c1e799d36e8f7f2
Autor:
Frédérique Rodieux, Flavia Storelli, François Curtin, Sergio Manzano, Alain Gervaix, Klara M. Posfay-Barbe, Jules Desmeules, Youssef Daali, Caroline F. Samer
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1227 (2023)
Following the contraindication of codeine use in children, increasing use of tramadol has been observed in pain management protocols. However, tramadol’s pharmacokinetics (PK) and pharmacodynamics are influenced by cytochrome P450 (CYP)2D6 activity
Externí odkaz:
https://doaj.org/article/4ca28190e4124db0973d33441f387fe7
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
While morphine is the gold standard treatment for severe nociceptive pain in children, hydromorphone is increasingly prescribed in this population. This review aims to assess available knowledge about hydromorphone and explore the evidence for its sa
Externí odkaz:
https://doaj.org/article/e373dfbf260844ee93fb09a32738f4fb
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/0280756c165d4f08916c0c02b44ca9d9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Available in-vitro and animal studies indicate that inflammation impacts cytochromes P450 (CYP) activity via multiple and complex transcriptional and post-transcriptional mechanisms, depending on the specific CYP isoforms and the nature o
Externí odkaz:
https://doaj.org/article/5ffe811d918f48c8af530e24354d6afd
Autor:
Alexandre Piletta-Zanin, Aurélie De Mul, Nathalie Rock, Pierre Lescuyer, Caroline F. Samer, Frédérique Rodieux
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tacrolimus is a calcineurin inhibitor characterized by a narrow therapeutic index and high intra- and inter-individual pharmacokinetic variability. Therapeutic drug monitoring in whole-blood is the standard monitoring procedure. However, tacrolimus e
Externí odkaz:
https://doaj.org/article/9fc7260742c0481399e562559315d3da
Autor:
Kuntheavy Ing Lorenzini, Jules Desmeules, Victoria Rollason, Stéphane Bertin, Marie Besson, Youssef Daali, Caroline F. Samer
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pharmacokinetic variability is a major source of differences in drug response and can be due to genetic variants and/or drug-drug interactions. Cytochromes P450 are among the most studied enzymes from a pharmacokinetic point of view. Their activity c
Externí odkaz:
https://doaj.org/article/7b1df3ccab264a558f2d97d9f0f591e6
Autor:
Frédérique Rodieux, Laszlo Vutskits, Klara M. Posfay-Barbe, Walid Habre, Valérie Piguet, Jules A. Desmeules, Caroline F. Samer
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Children represent a vulnerable population in which management of nociceptive pain is complex. Drug responses in children differ from adults due to age-related differences. Moreover, therapeutic choices are limited by the lack of indication for a num
Externí odkaz:
https://doaj.org/article/52bce293473f4f518e5189803718b9af
Autor:
Caroline F. Samer, Evangelia Passia, Nathalie Rock, Riccardo E. Pfister, Kuntheavy R. Ing Lorenzini, Jules Desmeules
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
We report a case of carbamazepine withdrawal syndrome following in utero exposure to carbamazepine related to a pharmacogenetic predisposition factor. The infant was born at 37 1/7 weeks’ gestation by cesarean section to a mother treated for epilep
Externí odkaz:
https://doaj.org/article/df950351ba984a748436610fe50f4e0a
Autor:
Jean Terrier, Frederic Gaspar, Pierre Fontana, Youssef Daali, Jean-Luc Reny, Chantal Csajka, Caroline F. Samer
Publikováno v:
The American Journal of Medicine. 136:216-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59b7ebdf88947a1ea9f1ddca72e2f301
https://doi.org/10.1016/j.amjmed.2022.11.001
https://doi.org/10.1016/j.amjmed.2022.11.001