Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Caroline F Dalton"'
Autor:
Helene A. Fachim, Kirk Siddals, Nagaraj Malipatil, Rachelle P Donn, Gabriela YC Moreno, Caroline F Dalton, Safwaan Adam, Handrean Soran, J Martin Gibson, Adrian H Heald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 96-107 (2020)
Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired glucose regulation (IGR), the results were compared to bariatric surgery, considering it an inte
Externí odkaz:
https://doaj.org/article/49a560e0bdf742dda62322bf8a172f6c
Autor:
Helene A. Fachim, Camila M. Loureiro, Kirk Siddals, Caroline F Dalton, Gavin P. Reynolds, J. Martin Gibson, Zhen Bouman Chen, Adrian H. Heald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 443-453 (2020)
We analysed if levels of four miRNAs would change after a lifestyle intervention involving dietary and exercises in prediabetes. MiRNAs previously shown to be associated with diabetes (Let-7a, Let-7e, miR-144 and miR-92a) were extracted from serum pr
Externí odkaz:
https://doaj.org/article/a32d02250bf248a7aaeeb77bf5f8f5a1
Autor:
Camila Marcelino Loureiro, Fabiana Corsi-Zuelli, Helene Aparecida Fachim, Rosana Shuhama, Adrielle Martins de Oliveira, Paulo Rossi Menezes, Caroline F. Dalton, Paulo Louzada-Junior, Sintia Iole Belangero, Fernanda Coeli-Lacchini, Gavin P. Reynolds, Riccardo Lacchini, Cristina Marta Del-Ben
Publikováno v:
Brazilian Journal of Psychiatry, Vol 45, Iss 3, Pp 226-235 (2023)
Objectives: Gene-environment interactions increase the risk of psychosis. The objective of this study was to investigate gene-gene and gene-environment interactions in psychosis, including single nucleotide variants (SNVs) of dopamine-2 receptor (D2R
Externí odkaz:
https://doaj.org/article/360ff7c6d1c14dd68c85411fba4c41c7
Autor:
Helene A. Fachim, Nagaraj Malipatil, Kirk Siddals, Rachelle Donn, Gabriela Y. Cortés, Caroline F. Dalton, J. Martin Gibson, Adrian H. Heald
Publikováno v:
Epigenomes, Vol 6, Iss 1, p 7 (2022)
BDNF signalling in hypothalamic neuronal circuits is thought to regulate mammalian food intake. In light of this, we investigated how a lifestyle intervention influenced serum levels and DNA methylation of BDNF gene in fat tissue and buffy coat of ND
Externí odkaz:
https://doaj.org/article/db21d75df4dd47a4866f820293d6ca91
Autor:
Teresa R. Taylor-Whiteley, Christine L. Le Maitre, James A. Duce, Caroline F. Dalton, David P. Smith
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 4 (2019)
Extensive loss of dopaminergic neurons and aggregation of the protein α-synuclein into ubiquitin-positive Lewy bodies represents a major neuropathological hallmark of Parkinson's disease (PD). At present, the generation of large nuclear-associated L
Externí odkaz:
https://doaj.org/article/42b8eb5ea8f5428785fecf6ccddb50fa
Publikováno v:
Journal of Psychopharmacology. 36:238-244
Background: N-methyl-d-aspartate receptor (NMDAR) dysfunction is implicated in schizophrenia, and NMDAR antagonists, such as phencyclidine (PCP), can induce behaviours that mimic aspects of the disorder. Aims: We investigated DNA methylation of Grin1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e51ea3db1e42c36f4b8ab8e56fa404
https://doi.org/10.1177/02698811211069109
https://doi.org/10.1177/02698811211069109
Autor:
Paulo Louzada-Junior, Camila Marcelino Loureiro, Rosana Shuhama, Cristina Marta Del-Ben, Gavin P. Reynolds, Helene A Fachim, Sâmia R.L. Joca, Paulo Rossi Menezes, Caroline F. Dalton, Fabiana Corsi-Zuelli
Publikováno v:
Loureiro, C M, Fachim, H A, Corsi-Zuelli, F, Shuhama, R, Joca, S, Menezes, P R, Dalton, C F, Del-Ben, C M, Louzada-Junior, P & Reynolds, G P 2020, ' Epigenetic-mediated N-methyl-D-aspartate receptor changes in the brain of isolated reared rats ', Epigenomics, vol. 12, no. 22, pp. 1983-1997 . https://doi.org/10.2217/epi-2020-0151
Aim: We investigated: Grin1, Grin2a, Grin2b DNA methylation; NR1 and NR2 mRNA/protein in the prefrontal cortex (PFC); and hippocampus of male Wistar rats exposed to isolation rearing. Materials & methods: Animals were kept isolated or grouped (n = 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce2937ed020aece6d1773eeb8b3a90a
https://doi.org/10.2217/epi-2020-0151
https://doi.org/10.2217/epi-2020-0151
Autor:
J. Martin Gibson, Helene A Fachim, Adrian H. Heald, Handrean Soran, Kirk Siddals, Nagaraj Malipatil, Caroline F. Dalton, Rachelle Donn, Safwaan Adam, Gabriela Y C Moreno
Publikováno v:
Adipocyte
Fachim, H A, Siddals, K, Malipatil, N, Donn, R P, Moreno, G Y, Dalton, C F, Adam, S, Soran, H, Gibson, J M & Heald, A H 2020, ' Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation ', Adipocyte, vol. 9, no. 1, pp. 96-107 . https://doi.org/10.1080/21623945.2020.1732513
Adipocyte, Vol 9, Iss 1, Pp 96-107 (2020)
Fachim, H A, Siddals, K, Malipatil, N, Donn, R P, Moreno, G Y, Dalton, C F, Adam, S, Soran, H, Gibson, J M & Heald, A H 2020, ' Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation ', Adipocyte, vol. 9, no. 1, pp. 96-107 . https://doi.org/10.1080/21623945.2020.1732513
Adipocyte, Vol 9, Iss 1, Pp 96-107 (2020)
© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de0f25021b58bb0be49e1da23b7ef8a
https://doi.org/10.1080/21623945.2020.1732513
https://doi.org/10.1080/21623945.2020.1732513
Autor:
Gemma Phillips, Matthew Cross, Mike Weed, Thomas Edwards, Clive B. Beggs, Lucia Bonadonna, Lisa Hodgson, Federica Valeriani, Jon Patricios, Alfonso Jimenez, Vincenzo Romano Spica, Ben Jones, Simon Kemp, Caroline F. Dalton, Robert Copeland, Keith Stokes, Emily R. Adams
Publikováno v:
South African Journal of Sports Medicine; Vol. 33 No. 1 (2021)
The coronavirus disease 2019 (COVID-19) pandemic has caused disruption to professional and recreational sports across the world. The SARS-CoV-2 virus can be transmitted by relatively large respiratory droplets that behave ballistically, and exhaled a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1b508763b46fa190d54eed49bdca02
https://eprints.leedsbeckett.ac.uk/id/eprint/7917/1/EndToEndSARSCoV2TransmissionRisksInSportPV-JONES.pdf
https://eprints.leedsbeckett.ac.uk/id/eprint/7917/1/EndToEndSARSCoV2TransmissionRisksInSportPV-JONES.pdf
Autor:
Caroline F. Dalton, Anouska Carter, Ian M. Lahart, Mostafa Metwally, Deborah Harrop, Amie Woodward, David Broom, Markos Klonizakis
Publikováno v:
Journal of Diabetes and Metabolic Disorders
Purpose Women with polycystic ovary syndrome (PCOS) exhibit many metabolic abnormalities that are associated with an increased cardiovascular disease risk. Exercise may promote improvements in lipid profile and insulin sensitivity in women with PCOS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be185849e77614e64c817f926ce25c7
https://doi.org/10.1007/s40200-019-00425-y
https://doi.org/10.1007/s40200-019-00425-y