Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Caroline End"'
Autor:
Jan Mollenhauer, Enno C. I. Veerman, Floris J. Bikker, Caroline End, Kamran Nazmi, Rainer Wittig, Antoon J. M. Ligtenberg, Marcus Renner, Stefan Lyer, Arie V. Nieuw Amerongen, Stephanie Blaich, Annemarie Poustka
Publikováno v:
Immunogenetics
Bikker, F J, End, C, Ligtenberg, A J M, Blaich, S, Lyer, S, Renner, M, Wittig, R, Nazmi, K, van Nieuw Amerongen, A, Poustka, A, Veerman, E C I & Mollenhauer, J 2017, ' The scavenging capacity of DMBT1 is impaired by germline deletions ', Immunogenetics, vol. 69, no. 6, pp. 401-407 . https://doi.org/10.1007/s00251-017-0982-x
Immunogenetics, 69(6), 401-407. Springer Verlag
Bikker, F J, End, C, Ligtenberg, A J M, Blaich, S, Lyer, S, Renner, M, Wittig, R, Nazmi, K, van Nieuw Amerongen, A, Poustka, A, Veerman, E C I & Mollenhauer, J 2017, ' The scavenging capacity of DMBT1 is impaired by germline deletions ', Immunogenetics, vol. 69, no. 6, pp. 401-407 . https://doi.org/10.1007/s00251-017-0982-x
Immunogenetics, 69(6), 401-407. Springer Verlag
The Scavenger Receptor Cysteine-Rich (SRCR) proteins are an archaic group of proteins characterized by the presence of multiple SRCR domains. They are membrane-bound or secreted proteins, which are generally related to host defense systems in animals
Publikováno v:
BIOspektrum. 26:555-555
Anlass des Erratums: Unter dem Original-Artikel hat die Funding Note gefehlt mit dem Hinweis bzgl. der Open Access Licence
Publikováno v:
BIOspektrum. 20:70-72
Cell-free protein synthesis (CFPS) is an important tool for molecular biology and can be used in applied and basic research. Especially as a high throughput technology for functional genomics and proteomics, CFPS systems offer a significant advantage
Autor:
Caroline End, Philip Rosenstiel, Annemarie Poustka, Antoon J. M. Ligtenberg, Gaby Bergmann, Melanie Hudler, Christian Sina, Floris J. Bikker, Frank Autschbach, Nikolaus Gassler, Arie V. Nieuw Amerongen, Marcus Renner, Uffe Holmskov, Axel Benner, Andre Franke, Stefan Lyer, Stefan Schreiber, Jan Mollenhauer, Mathias Hafner, Peter Schirmacher, Burkhard Helmke, Petra Kioschis, Stephanie Blaich
Publikováno v:
European Journal of Immunology. 39:833-842
Deleted in malignant brain tumors 1 (DMBT1) is a secreted glycoprotein displaying a broad bacterial-binding spectrum. Recent functional and genetic studies linked DMBT1 to the suppression of LPS-induced TLR4-mediated NF-kappaB activation and to the p
Autor:
Hanna Müller, Ashwini Bhandiwad, Caroline End, Jan Mollenhauer, Marcus Renner, Johannes Poeschl, Mathias Hafner, Christel Weiss, Annemarie Poustka, Nikolaus Gassler, Burkhard Helmke
Publikováno v:
Müller, H, End, C, Weiss, C, Renner, M, Bhandiwad, A, Helmke, B M, Gassler, N, Hafner, M, Poustka, A, Mollenhauer, J & Poeschl, J 2007, ' Respiratory Deleted in Malignant Brain Tumours 1 (DMBT1) levels increase during lung maturation and infection. ', Clinical and Experimental Immunology, vol. 151, no. 1, pp. 123-9 . https://doi.org/10.1111/j.1365-2249.2007.03528.x
Summary Deleted in Malignant Brain Tumours 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds and aggregates various bacteria and viruses in vitro. Studies in adults have shown that DMBT1 is expressed mainly by mucosal epithe
Publikováno v:
Inmunología. 26:193-209
Epidemiological and molecular studies have pointed to links between infection, inflammation and cancer, which appear to converge at the molecular level in mechanisms associated with innate immunity. Here, the present knowledge about the secreted scav
Autor:
Stefan Schreiber, Caroline End, Burkhard Helmke, Philip Rosenstiel, Marcus Renner, Andreas Till, Jan Mollenhauer, Mathias Hafner, Petra Kioschis, Stefan Lyer, Frank Autschbach, Susanna Nikolaus, Ulrich R. Fölsch, Christian Sina, Stephan Hellmig, Annemarie Poustka, Peter Schirmacher
Publikováno v:
Rosenstiel, P, Sina, C, End, C, Renner, M, Lyer, S, Till, A, Hellmig, S, Nikolaus, S, Fölsch, U R, Helmke, B, Autschbach, F, Schirmacher, P, Kioschis, P, Hafner, M, Poustka, A, Mollenhauer, J & Schreiber, S 2007, ' Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion ', Journal of Immunology, vol. 178, no. 12, pp. 8203-11 .
Mucosal epithelial cell layers are constantly exposed to a complex resident microflora. Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of secreted scavenger receptor cysteine-rich proteins and is considered to be involved in host de
Autor:
Annemarie Poustka, Gaby Bergmann, Arie V. Nieuw Amerongen, Vito Annese, Uffe Holmskov, Antoon J. M. Ligtenberg, Mauro D'Amato, Stefan Lyer, Inge Krebs, Frank Autschbach, Jens Madsen, Stephanie Blaich, Anna Latiano, Petra Kioschis, Floris J. Bikker, Rainer Wittig, Melanie Hudler, Sabine Gronert-Sum, Olga Strobel-Freidekind, Peter Schirmacher, Marcus Renner, Jan Mollenhauer, Caroline End, Burkhard Helmke, Nikolaus Gassler, Frank Hilberg, Axel Benner, Mathias Hafner
Publikováno v:
Renner, M, Bergmann, G, Krebs, I, End, C, Lyer, S, Hilberg, F, Helmke, B, Gassler, N, Autschbach, F, Bikker, F, Strobel-Freidekind, O, Gronert-Sum, S, Benner, A, Blaich, S, Wittig, R, Hudler, M, Ligtenberg, A J, Madsen, J, Holmskov, U, Annese, V, Latiano, A, Schirmacher, P, Amerongen, A V N, D'Amato, M, Kioschis, P, Hafner, M, Poustka, A & Mollenhauer, J 2007, ' DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease ', Gastroenterology, vol. 133, no. 5, pp. 1499-509 . https://doi.org/10.1053/j.gastro.2007.08.007
Gastroenterology, 133, 1499-1509. W.B. Saunders Ltd
Renner, M, Bergmann, G, Krebs, I, End, C, Lyer, S, Hillberg, F, Helmke, B, Gassler, N, Autschbach, F, Bikker, F J, Strobel-Freidekind, O, Gronert-Sum, S, Benner, A, Blaich, S, Wittig, R, Hudler, M, Ligtenberg, A J M, Madsen, J, Holmskov, U, Annese, V, Latiano, A, Schirmacher, P, van Nieuw Amerongen, A, D'Amato, M, Kioschis, P, Hafner, M, Poustka, A & Mollenhauer, J 2007, ' DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease ', Gastroenterology, vol. 133, pp. 1499-1509 . https://doi.org/10.1053/j.gastro.2007.08.007
Gastroenterology, 133, 1499-1509. W.B. Saunders Ltd
Renner, M, Bergmann, G, Krebs, I, End, C, Lyer, S, Hillberg, F, Helmke, B, Gassler, N, Autschbach, F, Bikker, F J, Strobel-Freidekind, O, Gronert-Sum, S, Benner, A, Blaich, S, Wittig, R, Hudler, M, Ligtenberg, A J M, Madsen, J, Holmskov, U, Annese, V, Latiano, A, Schirmacher, P, van Nieuw Amerongen, A, D'Amato, M, Kioschis, P, Hafner, M, Poustka, A & Mollenhauer, J 2007, ' DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease ', Gastroenterology, vol. 133, pp. 1499-1509 . https://doi.org/10.1053/j.gastro.2007.08.007
Udgivelsesdato: 2007-Nov BACKGROUND & AIMS: Impaired mucosal defense plays an important role in the pathogenesis of Crohn's disease (CD), one of the main subtypes of inflammatory bowel disease (IBD). Deleted in malignant brain tumors 1 (DMBT1) is a s
Autor:
Jolanda M.A. de Blieck-Hogervorst, Floris J. Bikker, Antoon J. M. Ligtenberg, Wim van 't Hof, Arie V. Nieuw Amerongen, Kamran Nazmi, Jan Mollenhauer, Stephanie Blaich, Annemarie Poustka, Rainer Wittig, Petra Kioschis, Enno C. I. Veerman, Caroline End, Stephan Lyer, Marcus Renner
Publikováno v:
Bikker, F J, Ligtenberg, A J M, End, C, Renner, M, Blaich, S, Lyer, S, Wittig, R, van 't Hof, W, Veerman, E C I, Nazmi, K, de Blieck-Hogervorst, J M A, Kioschis, P, van Nieuw Amerongen, A, Poutska, A M & Mollenhauer, J 2004, ' Bacteria-binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains ', The Journal of Biological Chemistry, vol. 279, pp. 47699-47703 . https://doi.org/10.1074/jbc.M406095200
Bikker, F J, Ligtenberg, A J M, End, C, Renner, M, Blaich, S, Lyer, S, Wittig, R, van't Hof, W, Veerman, E C I, Nazmi, K, de Blieck-Hogervorst, J M A, Kioschis, P, Nieuw Amerongen, A V, Poustka, A & Mollenhauer, J 2004, ' Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. ', Journal of Biological Chemistry, vol. 279, no. 46, pp. 47699-703 . https://doi.org/10.1074/jbc.M406095200
The Journal of Biological Chemistry, 279, 47699-47703. American Society for Biochemistry and Molecular Biology Inc.
Bikker, F J, Ligtenberg, A J M, End, C, Renner, M, Blaich, S, Lyer, S, Wittig, R, van't Hof, W, Veerman, E C I, Nazmi, K, de Blieck-Hogervorst, J M A, Kioschis, P, Nieuw Amerongen, A V, Poustka, A & Mollenhauer, J 2004, ' Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. ', Journal of Biological Chemistry, vol. 279, no. 46, pp. 47699-703 . https://doi.org/10.1074/jbc.M406095200
The Journal of Biological Chemistry, 279, 47699-47703. American Society for Biochemistry and Molecular Biology Inc.
Udgivelsesdato: 2004-Nov-12 The scavenger receptor cysteine-rich (SRCR) proteins form an archaic group of metazoan proteins characterized by the presence of SRCR domains. These proteins are classified in group A and B based on the number of conserved
Autor:
Pernille Lund Hansen, Jesper B. Moeller, Steffen J. Schmidt, Uffe Holmskov, Jan Mollenhauer, Stephanie Blaich, Caroline End
Publikováno v:
Lund Hansen, P, Blaich, S, End, C, Schmidt, S, Møller, J B, Holmskov, U & Mollenhauer, J 2011, ' The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery ', Chemical Communications, vol. 47, pp. 188-190 . https://doi.org/10.1039/c0cc02186e
Liposomal nucleic acid delivery is a preferred option for therapeutic settings. The cellular pattern recognition molecule DMBT1, secreted at high levels in various diseases, and synthetic mimics efficiently inhibit liposomal nucleic acid delivery to