Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caroline E. Lyon"'
Autor:
Motaher Hossain, Kamrul Islam, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Ana A Weil, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Daniel T Leung, Andrew S Azman, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007874 (2019)
BackgroundAntibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae may protect against cholera; however, little is known about this immune response in infected immunologically naïve humans.MethodologyWe measured serum anti-OSP antibod
Externí odkaz:
https://doaj.org/article/916ab507d03948078640a876d62ccc61
Autor:
Kamrul Islam, Motaher Hossain, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Regina C LaRocque, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Douglas Haney, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006376 (2018)
BACKGROUND:Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP)
Externí odkaz:
https://doaj.org/article/5a7a697cf70e4170a1b24a53b409d81b
A site assessment tool for inpatient controlled human infection models for enteric disease pathogens
Autor:
A. Louis Bourgeois, Sandra D. Isidean, Katherine J Detizio, Chad K. Porter, Robert W. Frenck, Caroline E. Lyon, Wilbur H. Chen, Ashley Alcala, Nicole Maier, Kurt Hanevik, Kayla J. Testa, Frederick K. Sawe, Kawsar R. Talaat, Ramiro L. Gutierrez, Robert W. Kaminski, Beth D. Kirkpatrick
Publikováno v:
Clinical Trials
The use of the controlled human infection model to facilitate product development and to advance understanding of host-pathogen interactions is of increasing interest. While administering a virulent (or infective) organism to a susceptible host neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841989531855a197f4b703a841829d0b
https://hdl.handle.net/11250/2985593
https://hdl.handle.net/11250/2985593
Autor:
Marc Gurwith, Mitchell B. Cohen, Beth D. Kirkpatrick, Jakub K. Simon, Marcelo B. Sztein, Douglas Haney, Jason B. Harris, Glenn Ishioka, Myron M. Levine, Caroline E. Lyon, Wilbur H. Chen, Michael Lock
Publikováno v:
Vaccine. 36:2768-2773
Background The single-dose live attenuated vaccine CVD 103-HgR protects against experimental Vibrio cholerae infection in cholera-naive adults for at least 6 months after vaccination. While vaccine-induced vibriocidal seroconversion is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0996f39e92a2d96f428a3c86dc666ba1
https://doi.org/10.1016/j.vaccine.2018.04.011
https://doi.org/10.1016/j.vaccine.2018.04.011
Autor:
Michael Lock, Wilbur H. Chen, Beth D. Kirkpatrick, Douglas Haney, Myron M. Levine, Marc Gurwith, Caroline E. Lyon, Mitchell B. Cohen, Sharon M. Tennant, Jakub K. Simon, David Galloway, Robert A. Kessler, R H Hall, Flora Szabo, Marcela F. Pasetti, Rebecca C. Brady
Publikováno v:
Clinical Infectious Diseases. 62:1329-1335
Background. No licensed cholera vaccine is presently available in the United States. Cholera vaccines available in other countries require 2 spaced doses. A single-dose cholera vaccine that can rapidly protect short-notice travelers to high-risk area
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3079759cca64f6d9187114a5284fdbc
https://doi.org/10.1093/cid/ciw145
https://doi.org/10.1093/cid/ciw145
Autor:
Catherine J. Luke, Marya P. Carmolli, Beth D. Kirkpatrick, Cecilia M. Tibery, Palmtama L. Grier, Adrienne P. Jarvis, Catherine J. Larsson, Kristen K. Pierce, Mary Claire Walsh, Caroline E. Lyon, Steven S. Whitehead, Anna P. Durbin, Janece M. Lovchik, Noreen A. Hynes, Ellen A. Fraser, Matthew Jo, Beulah P. Sabundayo, Dan Elwood, Kanta Subbarao, Sean A. Diehl
Publikováno v:
Journal of Infectious Diseases. 212:702-710
Background. The 4 serotypes of dengue virus, DENV-1–4, are the leading cause of arboviral disease globally. The ideal dengue vaccine would provide protection against all serotypes after a single dose. Methods. Two randomized, placebo-controlled tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c15abafaece3c03069db0892f5addf
https://doi.org/10.1093/infdis/jiv082
https://doi.org/10.1093/infdis/jiv082
Autor:
Wilbur H. Chen, Jason B. Harris, Beth D. Kirkpatrick, Mitchell B. Cohen, Marc Gurwith, Stephen B. Calderwood, Leslie M. Mayo-Smith, Michael Lock, Douglas Haney, Myron M. Levine, Jakub K. Simon, Caroline E. Lyon
Publikováno v:
Clinical and Vaccine Immunology. 24
One potential advantage of live attenuated bacterial vaccines is the ability to stimulate responses to antigens which are only expressed during the course of infection. To determine whether the live attenuated cholera vaccine CVD 103-HgR (Vaxchora) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ebe463d59c3ae08ca179483877bb15
https://doi.org/10.1128/cvi.00470-16
https://doi.org/10.1128/cvi.00470-16
Autor:
Ana A. Weil, Jakub K. Simon, Michael Lock, Motaher Hossain, Jason B. Harris, Taufiqur Rahman Bhuiyan, Andrew S. Azman, Peng Xu, Mitchell B. Cohen, Kamrul Islam, Richelle C. Charles, Daniel T. Leung, Myron M. Levine, Beth D. Kirkpatrick, Caroline E. Lyon, Edward T. Ryan, Wilbur H. Chen, Firdausi Qadri, Meagan Kelly, Stephen B. Calderwood, Leslie M. Mayo Smith, Pavol Kováč, Marc Gurwith
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007874 (2019)
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007874 (2019)
Background Antibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae may protect against cholera; however, little is known about this immune response in infected immunologically naïve humans. Methodology We measured serum anti-OSP anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299c1cbacb46ac17dd679ed0d601bdc7
https://doi.org/10.1371/journal.pntd.0007874
https://doi.org/10.1371/journal.pntd.0007874
Autor:
Beth D. Kirkpatrick, Leslie M. Mayo Smith, Pavol Kováč, Marc Gurwith, Jason B. Harris, Stephen B. Calderwood, Motaher Hossain, Kamrul Islam, Mitchell B. Cohen, Peng Xu, Jakub K. Simon, Myron M. Levine, Wilbur H. Chen, Caroline E. Lyon, Michael Lock, Edward T. Ryan, Firdausi Qadri, Douglas Haney, Regina C. LaRocque, Richelle C. Charles, Taufiqur Rahman Bhuiyan, Meagan Kelly
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006376 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bf9483ac5cd9ae3db85d6ba57135b3
https://doi.org/10.1371/journal.pntd.0006376
https://doi.org/10.1371/journal.pntd.0006376
Autor:
Caroline E. Lyon, Jonathan K. Ehrman, Clinton A. Brawner, Philip A. Ades, Patrick D. Savage, Steven J. Keteyian, Janice Y. Bunn
Publikováno v:
Circulation. 113:2706-2712
Background— Symptom-limited treadmill testing is commonly performed on entry to cardiac rehabilitation (CR) for its prognostic value and to design a safe and effective exercise program. Normative values for this evaluation are not available. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8550e2216242f4b694433d0b13d90d2b
https://doi.org/10.1161/circulationaha.105.606624
https://doi.org/10.1161/circulationaha.105.606624