Lhx1 is required for specification of the renal progenitor cell field.

Autor: M Cecilia Cirio, Zhao Hui, Caroline E Haldin, Chiara Cianciolo Cosentino, Carsten Stuckenholz, Xiongfong Chen, Sung-Kook Hong, Igor B Dawid, Neil A Hukriede

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18858 (2011)

In the vertebrate embryo, the kidney is derived from the intermediate mesoderm. The LIM-class homeobox transcription factor lhx1 is expressed early in the intermediate mesoderm and is one of the first genes to be expressed in the nephric mesenchyme.

Externí odkaz: https://doaj.org/article/3102822b6cc94763a1049ea3915ef634

The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney

Autor: Brant M. Weinstein, Sung-Kook Hong, Nathan D. Lawson, Igor B. Dawid, Caroline E. Haldin, Neil A. Hukriede

Publikováno v: Proceedings of the National Academy of Sciences. 102:18473-18478

Mutation of the gene encoding the Mediator component thyroid hormone receptor-associated protein (TRAP)230/MED12 affects the development of multiple systems in zebrafish embryogenesis. We isolated two ethylnitrosourea-induced alleles in the gene enco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e404b4841fa266a3026331b8dd3bf402
https://doi.org/10.1073/pnas.0509457102

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

Autor: Shunbin Xu, Caroline E. Haldin, Daniel A. Nicholson, Donald J. Zack, Peter E. Larsen, Karl J. Wahlin, Colleen Cowan, Sanja Turturro, David Valle, Stephen Lumayag, Beatrix Kovacs, P. Dane Witmer, Nicola J. Corbett

Publikováno v: Lumayag, S, Haldin, C E, Corbett, N J, Wahlin, K J, Cowan, C, Turturro, S, Larsen, P E, Kovacs, B, Witmer, P D, Valle, D, Zack, D J, Nicholson, D A & Xu, S 2013, ' Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 6, pp. E507-E516 . https://doi.org/10.1073/pnas.1212655110

The microRNA -183/96/182 cluster is highly expressed in the retina and other sensory organs. To uncover its in vivo functions in the retina, we generated a knockout mouse model, designated “ miR-183C GT/GT ,” using a gene-trap embryonic stem cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e968c4f14eb5929ec9f107749df1f14
https://doi.org/10.1073/pnas.1212655110

Lhx1 is required for specification of the renal progenitor cell field

Autor: Caroline E. Haldin, Neil A. Hukriede, Carsten Stuckenholz, Sung-Kook Hong, Chiara Cianciolo Cosentino, Igor B. Dawid, Zhao Hui, Xiongfong Chen, M. Cecilia Cirio

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18858 (2011)
PLoS ONE

In the vertebrate embryo, the kidney is derived from the intermediate mesoderm. The LIM-class homeobox transcription factor lhx1 is expressed early in the intermediate mesoderm and is one of the first genes to be expressed in the nephric mesenchyme.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eaf3679d11db333175cfc7cd308dbd
http://europepmc.org/articles/PMC3078140?pdf=render

Isolation and growth factor inducibility of the Xenopus laevis Lmx1b gene

Autor: Caroline E, Haldin, Sarjit, Nijjar, Karine, Massé, Mark W, Barnett, Elizabeth A, Jones

Publikováno v: The International journal of developmental biology. 47(4)

This paper reports the cloning of the full length Xenopus laevis Lmx1b gene, Xlmx1b. Xlmx1b is a LIM homeodomain protein with high conservation to homologues identified in human, mouse, hamster and chick. In situ hybridisation and RT-PCR analysis sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88317aae61ca37a339e277012e1208a4
https://pubmed.ncbi.nlm.nih.gov/12755330