Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caroline E. Graham"'
Autor:
Chooi-May Lai, N. Binz, Diego Guidolin, Sarah A. Dunlop, Yvonne K. Y. Lai, Weiyong Shen, Piroska E. Rakoczy, Domenico Ribatti, J. Eade, Caroline E. Graham
Publikováno v:
Diabetologia. 49:1690-1701
Vascular endothelial growth factor (VEGF) plays a pivotal role in the pathogenesis of diabetic retinopathy. We investigated whether transgenic mice with moderate VEGF expression in photoreceptors (trVEGF029) developed changes similar to diabetic reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b29d683102510e7519be54c53830f0
https://doi.org/10.1007/s00125-006-0274-8
https://doi.org/10.1007/s00125-006-0274-8
Autor:
Hugh Dawkins, Sarah Baxendale, Geoff Davis, Caroline E Graham, Caron Molster, April Rutkay, Wenxing Sun, Trinity Mahede
Publikováno v:
Orphanet Journal of Rare Diseases
Background People with neuromuscular disorders (NMD) exhibit weak coughs and are susceptible to recurrent chest infections and acute respiratory complications, the most frequent reasons for their unplanned hospital admissions. Mechanical insufflation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbda69da56ee8008dcd75265388e9cac
https://pubmed.ncbi.nlm.nih.gov/25943355
https://pubmed.ncbi.nlm.nih.gov/25943355
Autor:
Kurt Zatloukal, Manuel Posada, Marina Mora, Olaf Reiss, Caroline E Graham, Gareth Baynam, Anna Kole, Caron Molster, Kate Bushby, Franz Schaefer, Sharon F. Terry, Lucia Monaco, Yaffa R. Rubinstein, Domenica Taruscio, Bartha Maria Knoppers, Hanns Lochmüller, Mats G. Hansson, David Carpentieri, Hugh Dawkins, Matthew I. Bellgard
Rare diseases (RD) refer to a collection of approximately 5,000–8,000 individual diseases that have a low prevalence and are often genetic in origin. While RD can manifest throughout life, they frequently affect children and newborns. Common charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630693871d9582783db1b00373d486e6
https://hdl.handle.net/20.500.12105/15589
https://hdl.handle.net/20.500.12105/15589
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Diabetic retinopathy is a severe complication of diabetes leading to some degree of vision impairment in long-term diabetes sufferers. Currently, the most successful treatment available for diabetic retinopathy is laser photocoagulation, a therapy th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0553c2c87933529af2a809664a38f1
https://doi.org/10.1007/0-387-32442-9_29
https://doi.org/10.1007/0-387-32442-9_29
Publikováno v:
Advances in experimental medicine and biology. 572
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96f752775e9da0c3f977147bcf30c1bd
https://pubmed.ncbi.nlm.nih.gov/17249575
https://pubmed.ncbi.nlm.nih.gov/17249575
Autor:
Caroline E Graham, Marina Mora, Manuel Posada, Franz Schaefer, Olaf Reiss, Hugh Dawkins, Gareth Baynam, Anna Kole, Kate Bushby, Mats G. Hansson, Domenica Taruscio, Hanns Lochmüller, David Carpentieri, Sharon F. Terry, Kurt Zatloukal, Yaffa R. Rubinstein, Matthew I. Bellgard, Deborah Mascalzoni, Lucia Monaco, Caron Molster, Bartha Maria Knoppers
Publikováno v:
Journal of Biorepository Science for Applied Medicine. :1
Graham CE, Molster C, Baynam GS, et al. Journal of Biorepository Science for Applied Medicine. 2014;2:49–61.Author Deborah Mascalzoni from the Centre for Research Ethics and Bioethics, Department of Public Health and Caring Sciences, Uppsala Univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d645462a3e0387f30064ca66a5fbce5
https://doi.org/10.2147/bsam.s83421
https://doi.org/10.2147/bsam.s83421
RALDH3 (retinal dehydrogenase 3) was characterized by kinetic and binding studies, protein engineering, homology modelling, ligand docking and electrostatic-potential calculations. The major recognition determinant of an RALDH3 substrate was shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60b1db4fbd459ffebd8afcf11daa010
https://europepmc.org/articles/PMC1386004/
https://europepmc.org/articles/PMC1386004/
Autor:
Chooi-May Lai, Yvonne K. Y. Lai, Terence P. Speed, Weiyong Shen, Caroline E. Graham, P. Elizabeth Rakoczy, Ken M. Simpson, N. Binz
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(2)
Microarray-based gene expression analysis demonstrated that laser photocoagulation (LPC) of mouse eyes had a long-term effect on the expression of genes functionally related to tissue repair, cell migration, proliferation, ion, protein and nucleic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5094afb0a90edf4f671d1c2f4e55239c
https://pubmed.ncbi.nlm.nih.gov/16354724
https://pubmed.ncbi.nlm.nih.gov/16354724
Autor:
N. Binz, Weiyong Shen, Ian J. Constable, M. Brankov, Chris J Barry, Lyn Beazley, Caroline E. Graham, Sarah A. Dunlop, M. Gorbatov, Yvonne K. Y. Lai, Elizabeth Rakoczy, Chooi-May Lai, L.A. May
Publikováno v:
The British journal of ophthalmology. 89(7)
Aim: To generate a mouse model for slow progressive retinal neovascularisation through vascular endothelial growth factor (VEGF) upregulation. Methods: Transgenic mice were generated via microinjection of a DNA construct containing the human VEGF165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ad8eaf3978e426cbdf4c2eca8cb90c
https://pubmed.ncbi.nlm.nih.gov/15965177
https://pubmed.ncbi.nlm.nih.gov/15965177