Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Caroline E. Gargett"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Improvements in reproductive techniques have resulted in the live birth rates from IVF procedures increasing from 5% to approximately 30% in recent decades but has plateaued since. Emerging preclinical and clinical data implicates endometria
Externí odkaz:
https://doaj.org/article/b5328e0d979b4b3b829d3c0863a59977
Autor:
Meaghan J. Griffiths, Sarah A. Marshall, Fiona L. Cousins, Lauren R. Alesi, Jordan Higgins, Saranya Giridharan, Urooza C. Sarma, Ellen Menkhorst, Wei Zhou, Alison S. Care, Jacqueline F. Donoghue, Sarah J. Holdsworth-Carson, Peter A.W. Rogers, Evdokia Dimitriadis, Caroline E. Gargett, Sarah A. Robertson, Amy L. Winship, Karla J. Hutt
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and radiotherapy can damage the ovary and compromise fertility, yet the ability of cancer treatments
Externí odkaz:
https://doaj.org/article/ee2f5e90ec17471e8dc9f94a729ae7b3
Autor:
Tina Gorsek Sparovec, Udo R. Markert, Philipp Reif, Wolfgang Schoell, Gerit Moser, Julia Feichtinger, Zala Nikita Mihalic, Julia Kargl, Caroline E. Gargett, Daniela Gold
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102671- (2022)
Regeneration of the endometrial stromal compartment in premenopausal women is likely maintained by the perivascular endometrial mesenchymal stem/stromal cells (eMSC) expressing sushi domain containing 2 (SUSD2). The fate of SUSD2+ eMSC during pregnan
Externí odkaz:
https://doaj.org/article/c929efb8235b48f690b0814d482a44c3
Publikováno v:
Frontiers in Reproductive Health, Vol 3 (2022)
The human endometrium is a remarkable tissue, undergoing ~450 cycles of proliferation, differentiation, shedding (menstruation), repair, and regeneration over a woman's reproductive lifespan. Post-menstrual repair is an extremely rapid and scar-free
Externí odkaz:
https://doaj.org/article/b91656c3ff2a4ed1a2a558c6a371824d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The human endometrium undergoes approximately 450 cycles of proliferation, differentiation, shedding and regeneration over a woman’s reproductive lifetime. The regenerative capacity of the endometrium is attributed to stem/progenitor cells residing
Externí odkaz:
https://doaj.org/article/fe303f3c51434af79dce4a2769282525
Autor:
Raffaella Lucciola, Pavle Vrljicak, Shanti Gurung, Caitlin Filby, Saeedeh Darzi, Joanne Muter, Sascha Ott, Jan J. Brosens, Caroline E. Gargett
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endometrial mesenchymal stem cells (eMSC) drive the extraordinary regenerative capacity of the human endometrium. Clinical application of eMSC for therapeutic purposes is hampered by spontaneous differentiation and cellular senescence upon large-scal
Externí odkaz:
https://doaj.org/article/ce1d9ed3b6614cc29b04de419dd5d8d6
Autor:
Mahmood Bozorgmehr, Shanti Gurung, Saeedeh Darzi, Shohreh Nikoo, Somaieh Kazemnejad, Amir-Hassan Zarnani, Caroline E. Gargett
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
A highly proliferative mesenchymal stem/stromal cell (MSC) population was recently discovered in the dynamic, cyclically regenerating human endometrium as clonogenic stromal cells that fulfilled the International Society for Cellular Therapy (ISCT) c
Externí odkaz:
https://doaj.org/article/f39f7b9e916f4cbeb2bf4ef14ffde11f
Autor:
Shayanti Mukherjee, Saeedeh Darzi, Kallyanashis Paul, Fiona L. Cousins, Jerome A. Werkmeister, Caroline E. Gargett
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
PurposeTransvaginal meshes for the treatment of Pelvic Organ Prolapse (POP) have been associated with severe adverse events and have been banned for clinical use in many countries. We recently reported the design of degradable poly L-lactic acid-co-p
Externí odkaz:
https://doaj.org/article/4c55bd366ab7440783f00c7d5cc2f25c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Mesenchymal stem/stromal cells (MSCs) are multipotent cells with favorable properties for cell therapies and regenerative medicine. Human endometrium harbors a small population of perivascular, clonogenic MSCs (eMSCs) identified by the SUSD2 marker.
Externí odkaz:
https://doaj.org/article/7f4a5bc02d0f429dbaf8b5b4f56e7bbb
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 9, Pp 1127-1132 (2016)
Summary Human endometrium is a highly regenerative tissue, undergoing more than 400 cycles of proliferation, differentiation, and shedding during a woman's reproductive life. Adult stem cells, including mesenchymal stem/stromal cells (MSCs), are like
Externí odkaz:
https://doaj.org/article/ec0cae9626bd408c89d623b2aa7013ef