Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Caroline E. Cameron"'
Autor:
Sean Waugh, Caroline E. Cameron
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Syphilis, caused by Treponema pallidum subsp. pallidum, is a global health concern with increasing rates worldwide. Current prevention strategies, including screen-and-treat approaches, are not sufficient to resolve rising infection rates, emphasizin
Externí odkaz:
https://doaj.org/article/c041232d6a0f4f0596fbcd7bcfd8199f
Autor:
Simon Houston, Alloysius Gomez, Andrew Geppert, Azad Eshghi, Derek S. Smith, Sean Waugh, Darryl B. Hardie, David R. Goodlett, Caroline E. Cameron
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum ssp. pallidum, is technically challenging due to high sample complexity, difficulties with obtaining sufficient quantities of bacteria for analysis, and the
Externí odkaz:
https://doaj.org/article/994e5ae992d940738c395daf9c2e6db8
Autor:
Sean Waugh, Akash Ranasinghe, Alloysius Gomez, Simon Houston, Karen V. Lithgow, Azad Eshghi, Jenna Fleetwood, Kate M. E. Conway, Lisa A. Reynolds, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionSyphilis is a chronic, multi-stage infection caused by the extracellular bacterium Treponema pallidum ssp. pallidum. Treponema pallidum widely disseminates through the vasculature, crosses endothelial, blood–brain and placental barriers
Externí odkaz:
https://doaj.org/article/aafce8b765b64c3297f7d1cd1d8d04e1
Autor:
Helena Pětrošová, Abanoub Mikhael, Sophie Culos, Alexandre Giraud-Gatineau, Alloysius M. Gomez, Matthew E. Sherman, Robert K. Ernst, Caroline E. Cameron, Mathieu Picardeau, David R. Goodlett
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Lipid A is the hydrophobic component of bacterial lipopolysaccharide and an activator of the host immune system. Bacteria modify their lipid A structure to adapt to the surrounding environment and, in some cases, to evade recognition by host immune c
Externí odkaz:
https://doaj.org/article/5ce7c5c61323437980abf87027812af2
Autor:
Chenkai Li, Darcy Sutherland, S. Austin Hammond, Chen Yang, Figali Taho, Lauren Bergman, Simon Houston, René L. Warren, Titus Wong, Linda M. N. Hoang, Caroline E. Cameron, Caren C. Helbing, Inanc Birol
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Antibiotic resistance is a growing global health concern prompting researchers to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting attention again as therapeutic agents with promising uti
Externí odkaz:
https://doaj.org/article/c1bce5da554a4b7f99970badd19ff8ea
Autor:
Simon Houston, Ethan Schovanek, Kate M. E. Conway, Sarah Mustafa, Alloysius Gomez, Raghavendran Ramaswamy, Ayman Haimour, Martin J. Boulanger, Lisa A. Reynolds, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The etiological agent of syphilis, Treponema pallidum ssp. pallidum, is a highly invasive “stealth” pathogen that can evade the host immune response and persist within the host for decades. This obligate human pathogen is adept at establishing in
Externí odkaz:
https://doaj.org/article/6d731f08041b463f9a7832f694f354d6
Autor:
Karen V. Lithgow, Emily Tsao, Ethan Schovanek, Alloysius Gomez, Leigh Anne Swayne, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the mechanisms associated with T. pallidum traversal of endothelial barriers
Externí odkaz:
https://doaj.org/article/41389e2999cf459f9ab5ccc3962512a1
Autor:
Karen V. Lithgow, Brigette Church, Alloysius Gomez, Emily Tsao, Simon Houston, Leigh Anne Swayne, Caroline E. Cameron
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Treponema pallidum subsp. pallidum is the causative agent of syphilis, a human-specific sexually transmitted infection that causes a multistage disease with diverse clinical manifestations. Treponema pallidum undergoes rapid vascular dissemi
Externí odkaz:
https://doaj.org/article/57571949b48c4a86af8ec569bcdf5b56
Autor:
Wei-Chien Andrew Kao, Helena Pětrošová, Rhodaba Ebady, Karen V. Lithgow, Pablo Rojas, Yang Zhang, Yae-Eun Kim, Yae-Ram Kim, Tanya Odisho, Nupur Gupta, Annette Moter, Caroline E. Cameron, Tara J. Moriarty
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body. Identification of bacterial factors promoting dissemination is crucia
Externí odkaz:
https://doaj.org/article/24434a553c8f4861988c1a974bab078c
Autor:
Stephen A. Raverty, Linda D. Rhodes, Erin Zabek, Azad Eshghi, Caroline E. Cameron, M. Bradley Hanson, J. Pete Schroeder
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract In the Salish Sea, the endangered Southern Resident Killer Whale (SRKW) is a high trophic indicator of ecosystem health. Three major threats have been identified for this population: reduced prey availability, anthropogenic contaminants, and
Externí odkaz:
https://doaj.org/article/95caf627a1ab4ffa872f21c45fbce0da