Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caroline E. Bates"'
Autor:
Lesley C. McFarlane, Thomas C. Fardon, Caroline E. Bates, K. Haggart, Brian J. Lipworth, Daniel K. C. Lee
Publikováno v:
Chest. 127:851-860
There are no data comparing the relative effects of high-dose ciclesonide (CIC) and fluticasone propionate (FP) on airway and systemic outcomes in patients with moderate persistent asthma.We elected to evaluate the relative effects of CIC and FP on t
Publikováno v:
British Journal of Clinical Pharmacology. 58:26-33
There are no data comparing the relative efficacy of hydrofluoroalkane (HFA) formulations of ciclesonide (CIC) and fluticasone propionate (FP) on airway hyper-responsiveness, in mild-to-moderate persistent asthma. We therefore elected to evaluate the
Publikováno v:
British Journal of Clinical Pharmacology. 57:100-104
Aims The relationship between β2-adrenoceptor polymorphisms at positions 16 and 27, and the acute systemic β2-adrenoceptor effects of inhaled salbutamol is unclear. We therefore elected to evaluate the influence of common homozygous β2-adrenocepto
Autor:
Daniel K. C. Lee, Louise M. Cowan, Graeme P. Currie, Lesley C. McFarlane, Brian J. Lipworth, Caroline E. Bates
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 93(3)
Background The effects of high-dose fluticasone propionate therapy on dynamic cortisol stimulation in severe asthma are unknown. Objective To evaluate the human corticotropin-releasing factor (hCRF)–stimulated plasma cortisol response to fluticason
Publikováno v:
The Journal of allergy and clinical immunology. 111(2)
Background: Modern H 1 -antihistamines differ in their in vitro binding affinity, but their comparative in vivo bioactivity in asthmatic airways is unknown. Objectives: We compared clinically recommended doses of 3 H 1 -antihistamines on airway hyper
Publikováno v:
American journal of respiratory and critical care medicine. 167(9)
We evaluated whether montelukast conferred additive effects in patients with asthma receiving fluticasone/salmeterol (FP/SM) combination and FP alone. Twenty-two patients with mild to moderate asthma completed a double-blind, placebo-controlled study
Autor:
Daniel K. C. Lee, Graeme P. Currie, Caroline E. Bates, Catherine M. Jackson, Brian J. Lipworth
Publikováno v:
European journal of clinical pharmacology. 59(1)
Current guidelines advocate adding a long acting beta(2)-agonist (LABA) to an inhaled corticosteroid as an alternative to increasing the dose of the latter. Since it is unclear how this translates into effects on surrogate inflammatory markers, we ev
Autor:
K. Haggart, Graeme P. Currie, Rob Gray, Daniel K. C. Lee, Caroline E. Bates, Thomas C. Fardon, Brian J. Lipworth
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S119
Rationale We evaluated the comparative efficacy of HFA formulations of CIC and FP, assessing methacholine challenge, in addition to exhaled nitric oxide, lung function, diary cards and quality of life. Methods 19 mild-to-moderate asthmatics completed
Autor:
Brian J. Lipworth, Louise M. Cowan, Daniel K. C. Lee, Lesley C. McFarlane, Graeme P. Currie, Caroline E. Bates
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S120
Rationale We evaluated the human corticotrophin releasing factor (hCRF) stimulated plasma cortisol response to fluticasone propionate (FP) 2000μg daily in severe asthmatic and healthy subjects. Methods 10 severe asthmatic and 10 healthy subjects rec
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S35
Rationale We evaluated the Arg-16 and Gly-16 genotypes for the acute albuterol response following methacholine challenge, after the first and last doses of combination inhalers containing formoterol (FM) and salmeterol (SM). Methods Parallel groups o