Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Caroline D. Kusmierz"'
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 892-899 (2021)
Externí odkaz:
https://doaj.org/article/9bd1ddd905cf4f9085d50911478d6826
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 815-822 (2020)
Externí odkaz:
https://doaj.org/article/67b76e3adc7844fcbc5e35e322f6fc43
Publikováno v:
Bioconjugate Chemistry. 33:1803-1810
Publikováno v:
Nature Protocols. 17:327-357
Autor:
Sasha B. Ebrahimi, Devleena Samanta, Benjamin E. Partridge, Caroline D. Kusmierz, Ho Fung Cheng, Arabela A. Grigorescu, Jorge L. Chávez, Peter A. Mirau, Chad A. Mirkin
Publikováno v:
Angew Chem Int Ed Engl
The ability of aptamers to recognize a variety of different molecules has fueled their emergence as effective recognition agents to probe complex media and cells. Many detection strategies necessitate an aptamer binding to its target to result in a d
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 892-899 (2021)
ACS Central Science
ACS Central Science
Liposomal spherical nucleic acids (L-SNAs) show significant promise as cancer immunotherapeutics. L-SNAs are highly modular nanoscale assemblies defined by a dense, upright radial arrangement of oligonucleotides around a liposomal core. Herein, we es
Autor:
Ziyin Huang, Cassandra E. Callmann, Dai Horiuchi, Chad A. Mirkin, Lisa E. Cole, Caroline D. Kusmierz
Publikováno v:
Proc Natl Acad Sci U S A
Highly heterogenous cancers, such as triple-negative breast cancer (TNBC), remain challenging immunotherapeutic targets. Herein, we describe the synthesis and evaluation of immunotherapeutic liposomal spherical nucleic acids (SNAs) for TNBC therapy.
Autor:
Michelle H. Teplensky, Max E. Distler, Caroline D. Kusmierz, Michael Evangelopoulos, Haley Gula, Derek Elli, Anastasia Tomatsidou, Vlad Nicolaescu, Ian Gelarden, Anjana Yeldandi, Daniel Batlle, Dominique Missiakas, Chad A. Mirkin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(14)
Significance Using SARS-CoV-2 as a relevant case study for infectious disease, we investigate the structure–function relationships that dictate antiviral spherical nucleic acid (SNA) vaccine efficacy. We show that the SNA architecture can be rapidl
Publikováno v:
Small. :2300097
Autor:
Caroline D. Kusmierz, Chad A. Mirkin, Max E Distler, Michael Evangelopoulos, Katherine E. Bujold, Michelle H. Teplensky
Publikováno v:
J Am Chem Soc
Herein, a method for synthesizing and utilizing DNA dendrons to deliver biomolecules to living cells is reported. Inspired by high-density nucleic acid nanostructures, such as spherical nucleic acids, we hypothesized that small clusters of nucleic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544968a4d6c5ff332b3dad682c2c619e
https://europepmc.org/articles/PMC8582297/
https://europepmc.org/articles/PMC8582297/