Výsledky vyhledávání - "Caroline Couch"

Tug-of-War between DNA Chelation and Silver Agglomeration in DNA–Silver Cluster Chromophores

Autor: Jeffrey T. Petty, David Lewis, Savannah Carnahan, Dahye Kim, Caroline Couch

Publikováno v: The Journal of Physical Chemistry B. 126:3822-3830

Supramolecular chromophores form when a DNA traps silvers that then coalesce into clusters with discrete, molecular electronic states. However, DNA strands are polymeric ligands that disperse silvers and thus curb agglomeration. We study this competi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ad53ca96306829c0e7fd0239a67074
https://doi.org/10.1021/acs.jpcb.2c01054

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Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic

Autor: Caroline Couch, Grace E. Martin, Michael J. Edwards, Ryan M. Boudreau, Aaron P. Seitz, Erich Gulbins, Charles C. Caldwell, Katrin Anne Becker

Publikováno v: Biochimie. 141:91-96

Sphingosine is a natural sphingolipid found in membranes of all eukaryotic cells. In addition to its functions in cell signaling, sphingosine has broad-spectrum antimicrobial properties. Sphingosine's role as an antimicrobial is important in tissues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b738461d2891ee4771ac8f3c0d337c4c
https://doi.org/10.1016/j.biochi.2017.03.014

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Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke

Autor: Kay C. Igwe, Batool Rizvi, Adu Matory, Jan Claassen, Sachin Agarwal, Alexandra S. Reynolds, Gen Li, Christine Mauro, Angela Velasquez, Sander Connolly, David Roh, Andrey Eliseyev, Adam M. Brickman, Benjamin Rohaut, Soojin Park, Vincent Perlbarg, Murad Megjhani, Caroline Couch, Kevin Doyle

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-41042-2⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, 2019, 9, pp.4174. ⟨10.1038/s41598-019-41042-2⟩
Scientific Reports, Nature Publishing Group, 2019, 9, pp.4174. ⟨10.1038/s41598-019-41042-2⟩

BackgroundThe significance of deep structural lesions on level of consciousness early after intracerebral haemorrhage (ICH) is largely unknown.MethodsWe studied a consecutive series of patients with spontaneous ICH that underwent MRI within 7 days of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff38930e37eb03a12de149b82294761
https://hal.archives-ouvertes.fr/hal-02299911

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Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury

Autor: Kelly M Burger, Joshua U Okonkwo, J. Claassen, Angela Velazquez, Kevin Doyle, Benjamin Rohaut, David Roh, Adu Matory, Andrey Eliseyev, E. Sander Connolly, Sachin Agarwal, Caroline Couch, Murad Megjhani, Soojin Park, Jean-Rémi King

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, 2019, 380 (26), pp.2497-2505. ⟨10.1056/NEJMoa1812757⟩
New England Journal of Medicine, Massachusetts Medical Society, 2019, 380 (26), pp.2497-2505. ⟨10.1056/NEJMoa1812757⟩
Am J Respir Crit Care Med

Brain activation in response to spoken motor commands can be detected by electroencephalography (EEG) in clinically unresponsive patients. The prevalence and prognostic importance of a dissociation between commanded motor behavior and brain activatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464cb7b886152c36a792921b84a4f872
https://hal.science/hal-02299909

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Incidence and predictors of post-traumatic stress symptoms in a cohort of patients with intracerebral hemorrhage

Autor: Josephine U. Pucci, E. Sander Connolly, Caroline Couch, Vivek P. Gupta, Andrew L.A. Garton

Publikováno v: Clinical Neurology and Neurosurgery. 190:105657

Objectives Examine the incidence and predictors of PTSD symptoms in a cohort of patients with ICH. Patients and Methods This study uses a prospective cohort of 108 patients with complete follow-up data including a questionnaire regarding stress sympt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df945fc81b4082c08867eead584fc72c
https://doi.org/10.1016/j.clineuro.2019.105657

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Dispersion in Scores on the Richmond Agitation and Sedation Scale as a Measure of Delirium in Patients with Subdural Hematomas

Autor: Caroline Couch, Andrew Bauerschmidt, Stephanie Thompson, Soojin Park, David Roh, E. Sander Connolly, Kara Melmed, Sachin Agarwal, Jan Claassen, David Robinson

Publikováno v: Neurocritical care. 30(3)

BACKGROUND: Delirium is a frequent complication of critical illness, but its diagnosis is more difficult in brain-injured patients due to language impairment and disorders of consciousness. We conducted a prospective cohort study to determine whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c1d596155781dc8caa8d86429c8d6e
https://pubmed.ncbi.nlm.nih.gov/30506177

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Early myoclonus following anoxic brain injury

Autor: Vivek K. Moitra, William Roth, Daniel Brodie, Jan Claassen, LeRoy E. Rabbani, Alexandra S. Reynolds, Alex Presciutti, Caroline Couch, David Roh, Angela Velazquez, Sachin Agarwal, Manisha Holmes, Benjamin Rohaut, David Robinson, Soojin Park

Publikováno v: Neurology: Clinical Practice
Neurology: Clinical Practice, 2018, 8 (3), pp.249-256. ⟨10.1212/CPJ.0000000000000466⟩

BackgroundIt is unknown whether postanoxic cortical and subcortical myoclonus are distinct entities with different prognoses.MethodsIn this retrospective cohort study of 604 adult survivors of cardiac arrest over 8.5 years, we identified 111 (18%) pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e9af90dcff3a06499f044db7541d82
https://hal.archives-ouvertes.fr/hal-01865879

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