Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Caroline Castera-Ducros"'
Autor:
Nicolas Primas, Caroline Castera-Ducros, Romain Paoli-Lombardo, Christophe Curti, Fanny Mathias, Pascal Rathelot, Pascal Marchand, Patrice Vanelle
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 1, Pp 209-243 (2024)
The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held its 31st annual conference in August 2023 at the Faculty of Pharmacy of Aix-Marseille University, Marseille, France. There were 8 keynote presentations, 10 early career r
Externí odkaz:
https://doaj.org/article/31102bf7b86c4aaaa5206d2b658c0158
Autor:
Omar Khoumeri, Sébastien Hutter, Nicolas Primas, Caroline Castera-Ducros, Sandra Carvalho, Susan Wyllie, Mohamed Lotfi Efrit, Dimitri Fayolle, Marc Since, Patrice Vanelle, Pierre Verhaeghe, Nadine Azas, Hussein El-Kashef
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 878 (2024)
A series of 61 thiazolidine-2,4-diones bearing a styryl group at position 5 was synthesized in 2–5 steps and their structure was proved by elemental and spectral analyses. The compounds obtained were evaluated in vitro against the promastigote stag
Externí odkaz:
https://doaj.org/article/19bbdde0254342f6abec98d71ef49a9d
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Caroline Castera-Ducros, Inès Jacquet, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1633 (2023)
In continuation of our research program to develop original synthetic methods using TDAE methodology on nitroheterocyclic substrates, we were able to generate for the first time a stable carbanion in position 2 of the 5-nitroimidazole scaffold. Start
Externí odkaz:
https://doaj.org/article/9f9158897187433290e0cbdaba25f26e
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1613 (2023)
As part of our ongoing antikinetoplastid structure–activity relationship study focused on positions 2 and 8 of the 3-nitroimidazo[1,2-a]pyridine scaffold, we were able to introduce a phenylthioether moiety at both position 2 and position 8 in one s
Externí odkaz:
https://doaj.org/article/f58d35b14a0c426d88c30e519caa15b5
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 1, p M1573 (2023)
As part of our ongoing scaffold-hopping work on an antikinetoplastid 3-nitroimidazo[1,2-a]pyridine scaffold, we explored 3-nitroimidazo[1,2-b]pyridazine as a potential new antikinetoplastid series. Using conditions previously described by our lab, we
Externí odkaz:
https://doaj.org/article/0c445725dd5148d0b7e1e45358e35a5a
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet, Clotilde Boudot, Emilie Brenot, Caroline Castera-Ducros, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Bertrand Courtioux, Alexis Valentin, Pierre Verhaeghe, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 998 (2022)
An antileishmanial structure–activity relationship (SAR) study focused on positions 2 and 8 of the imidazo[1,2-a]pyridine ring was conducted through the synthesis of 22 new derivatives. After being screened on the promatigote and axenic amastigote
Externí odkaz:
https://doaj.org/article/83013cdfb1b946f190f6b3a926203f86
Autor:
Martine Maillard-Boyer, Caroline Castera-Ducros, Pierre Verhaeghe, France Sifredi, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molecules, Vol 15, Iss 4, Pp 2719-2729 (2010)
A series of new quinazoline derivatives bearing a vinylic chloride group on the 2-position was prepared by using a consecutive SRN1 / ERC1 radical strategy.
Externí odkaz:
https://doaj.org/article/078b25b94c9f4c6db35fd97177b5681b
Autor:
Christophe Jean, Iliona Hounliasso, Angèle Miscione, Mélanie Fuchs, Anne-Violette Lagarde, Christophe Curti, Morgane Dulac, Patrice Vanelle, Edouard Lamy, Caroline Castera-Ducros, Pascal Rathelot, Florence Peyron
Publikováno v:
Le Pharmacien Hospitalier et Clinicien. 56:387-395
Resume Introduction L’evaluation de la qualite du processus des preparations pharmaceutiques en conformite avec les Bonnes Pratiques de Preparations (BPP) a conduit a l’elaboration d’un outil d’audit et sa realisation dans les quatre preparat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f4a30cf73cc797f2ac127d18a70a48
https://doi.org/10.1016/j.phclin.2021.03.007
https://doi.org/10.1016/j.phclin.2021.03.007
Autor:
Patrick Thevin, Christophe Curti, Alexandre Benech, Christophe Jean, Edouard Lamy, Caroline Castera Ducros, Nicolas Primas, Pierre Bertault-Peres, Patrice Vanelle
Publikováno v:
PLOS ONE. 18:e0282164
Objective Erythromycin is a macrolide antibiotic that is also prescribed off-label in premature neonates as a prokinetic agent. There is no oral formulation with dosage and/or excipients adapted for these high-risk patients. Methods Clinical studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6a31efeabce244bbbba76466d28551
https://doi.org/10.1371/journal.pone.0282164
https://doi.org/10.1371/journal.pone.0282164
Autor:
Alexis Valentin, Pierre Verhaeghe, Patrice Vanelle, Sophie Corvaisier, Damián Muruzabal, Caroline Castera-Ducros, Nadine Azas, Sébastien Hutter, Emilie Pinault, Alexandre Destere, Alan H. Fairlamb, Clotilde Boudot, Cyril Fersing, Pascal Rathelot, Susan Wyllie, Sandra Bourgeade-Delmas, Alix Sournia-Saquet, Aurélie Malzert-Fréon, Julien Pedron, Bertrand Courtioux, Amaya Azqueta, Marc Since, Jean Luc Stigliani, Nicolas Primas, Carole Di Giorgio, Youssef Kabri, Romain Paoli-Lombardo
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
International audience; To study the antikinetoplastid 3-nitroimidazo[1,2-a]pyridine pharmacophore, a structure-activity relationship study was conducted through the synthesis of 26 original derivatives and their in vitro evaluation on both Leishmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da65e5f41670c644ea019b322c91450
https://hal.archives-ouvertes.fr/hal-02920293
https://hal.archives-ouvertes.fr/hal-02920293
