Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Caroline Castera Ducros"'
Autor:
Patrick Thevin, Christophe Curti, Alexandre Benech, Christophe Jean, Edouard Lamy, Caroline Castera Ducros, Nicolas Primas, Pierre Bertault-Peres, Patrice Vanelle
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0282164 (2023)
ObjectiveErythromycin is a macrolide antibiotic that is also prescribed off-label in premature neonates as a prokinetic agent. There is no oral formulation with dosage and/or excipients adapted for these high-risk patients.MethodsClinical studies of
Externí odkaz:
https://doaj.org/article/f97cb661961341bb8466362f7c3e1949
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet, Clotilde Boudot, Emilie Brenot, Caroline Castera-Ducros, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Bertrand Courtioux, Alexis Valentin, Pierre Verhaeghe, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 998 (2022)
An antileishmanial structure–activity relationship (SAR) study focused on positions 2 and 8 of the imidazo[1,2-a]pyridine ring was conducted through the synthesis of 22 new derivatives. After being screened on the promatigote and axenic amastigote
Externí odkaz:
https://doaj.org/article/83013cdfb1b946f190f6b3a926203f86
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank
Molbank, 2023, Molbank, 2023 (1), pp.M1573. ⟨10.3390/m1573⟩
Molbank, 2023, Molbank, 2023 (1), pp.M1573. ⟨10.3390/m1573⟩
As part of our ongoing scaffold-hopping work on an antikinetoplastid 3-nitroimidazo[1,2-a]pyridine scaffold, we explored 3-nitroimidazo[1,2-b]pyridazine as a potential new antikinetoplastid series. Using conditions previously described by our lab, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d6ffe86b8773c96e961fa485c2de59
https://amu.hal.science/hal-04115477/file/molbank-2023-M1573.pdf
https://amu.hal.science/hal-04115477/file/molbank-2023-M1573.pdf
Autor:
Christophe Jean, Iliona Hounliasso, Angèle Miscione, Mélanie Fuchs, Anne-Violette Lagarde, Christophe Curti, Morgane Dulac, Patrice Vanelle, Edouard Lamy, Caroline Castera-Ducros, Pascal Rathelot, Florence Peyron
Publikováno v:
Le Pharmacien Hospitalier et Clinicien. 56:387-395
Resume Introduction L’evaluation de la qualite du processus des preparations pharmaceutiques en conformite avec les Bonnes Pratiques de Preparations (BPP) a conduit a l’elaboration d’un outil d’audit et sa realisation dans les quatre preparat
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Caroline Castera-Ducros, Inès Jacquet, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank. 2023:M1633
In continuation of our research program to develop original synthetic methods using TDAE methodology on nitroheterocyclic substrates, we were able to generate for the first time a stable carbanion in position 2 of the 5-nitroimidazole scaffold. Start
Autor:
Martine Maillard-Boyer, Caroline Castera-Ducros, Pierre Verhaeghe, France Sifredi, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molecules, Vol 15, Iss 4, Pp 2719-2729 (2010)
A series of new quinazoline derivatives bearing a vinylic chloride group on the 2-position was prepared by using a consecutive SRN1 / ERC1 radical strategy.
Externí odkaz:
https://doaj.org/article/078b25b94c9f4c6db35fd97177b5681b
Autor:
Alexis Valentin, Pierre Verhaeghe, Patrice Vanelle, Sophie Corvaisier, Damián Muruzabal, Caroline Castera-Ducros, Nadine Azas, Sébastien Hutter, Emilie Pinault, Alexandre Destere, Alan H. Fairlamb, Clotilde Boudot, Cyril Fersing, Pascal Rathelot, Susan Wyllie, Sandra Bourgeade-Delmas, Alix Sournia-Saquet, Aurélie Malzert-Fréon, Julien Pedron, Bertrand Courtioux, Amaya Azqueta, Marc Since, Jean Luc Stigliani, Nicolas Primas, Carole Di Giorgio, Youssef Kabri, Romain Paoli-Lombardo
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
International audience; To study the antikinetoplastid 3-nitroimidazo[1,2-a]pyridine pharmacophore, a structure-activity relationship study was conducted through the synthesis of 26 original derivatives and their in vitro evaluation on both Leishmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da65e5f41670c644ea019b322c91450
https://hal.archives-ouvertes.fr/hal-02920293
https://hal.archives-ouvertes.fr/hal-02920293
Autor:
Line Seguy, Cyril Fersing, Sébastien Hutter, Marc Since, Alexandre Destere, Bertrand Courtioux, Julien Pedron, Sophie Corvaisier, Elisa Boutet-Robinet, Pascal Rathelot, Alexis Valentin, Alix Sournia-Saquet, Jean Yves Brossas, Caroline Castera-Ducros, Dominique Mazier, Sandra Bourgeade-Delmas, Aurélie Malzert-Fréon, Susan Wyllie, Romain Paoli-Lombardo, Clotilde Boudot, Patrice Vanelle, Jean Luc Stigliani, Nicolas Primas, Luc Paris, Nadine Azas, Emilie Pinault, Pierre Verhaeghe, Alan H. Fairlamb
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
International audience; An antikinetoplastid pharmacomodulation study was done at position 8 of a previously identified pharmacophore in 3-nitroimidazo[1,2-a]pyridine series. Twenty original derivatives bearing an alkynyl moiety were synthesized via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6cc3d229c60b69b5d7d326afce492d
https://hal.inrae.fr/hal-02899751
https://hal.inrae.fr/hal-02899751
Autor:
Christophe Curti, E. Bouillot, C. Belliardo, Patrice Vanelle, Pascal Rathelot, D. Heurte, Caroline Castera-Ducros
Publikováno v:
Le Pharmacien Hospitalier et Clinicien. 53:223-230
Resume Introduction Cette etude propose un etat des lieux de l’utilisation des medicaments a haut risque (MHR) au cours des differentes etapes de la prise en charge medicamenteuse (PECM), au sein des services d’hospitalisation conventionnelle adu
Autor:
Cyril, Fersing, Louise, Basmaciyan, Clotilde, Boudot, Julien, Pedron, Sébastien, Hutter, Anita, Cohen, Caroline, Castera-Ducros, Nicolas, Primas, Michèle, Laget, Magali, Casanova, Sandra, Bourgeade-Delmas, Mélanie, Piednoel, Alix, Sournia-Saquet, Valère, Belle Mbou, Bertrand, Courtioux, Élisa, Boutet-Robinet, Marc, Since, Rachel, Milne, Susan, Wyllie, Alan H, Fairlamb, Alexis, Valentin, Pascal, Rathelot, Pierre, Verhaeghe, Patrice, Vanelle, Nadine, Azas
Publikováno v:
ACS medicinal chemistry letters. 10(1)
[Image: see text] Twenty nine original 3-nitroimidazo[1,2-a]pyridine derivatives, bearing a phenylthio (or benzylthio) moiety at position 8 of the scaffold, were synthesized. In vitro evaluation highlighted compound 5 as an antiparasitic hit molecule