Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Caroline C. Overly"'
Publikováno v:
PLoS Biology, Vol 10, Iss 12, p e1001453 (2012)
This community page describes the database and associated Web application that comprise the Allen Human Brain Atlas, an open online resource that integrates genomic and anatomic human brain data.
Externí odkaz:
https://doaj.org/article/af7f4083312d452494b42eca58b39ad4
Publikováno v:
Trends in Neurosciences. 35:711-714
The Allen Human Brain Atlas is a freely available multimodal atlas of gene expression and anatomy comprising a comprehensive 'all genes-all structures' array-based dataset of gene expression and complementary in situ hybridization (ISH) gene expressi
Autor:
Susan M. Sunkin, Preston M. Cartagena, Robert Howard, Christian F. Beckmann, David Feng, Zeb Haradon, Chinh Dang, Angela L. Guillozet-Bongaarts, Derric Williams, Jeff Goldy, Yang Li, Rachel A. Dalley, Tracy Lemon, Darren Bertagnolli, Clifford R. Slaughterbeck, Simon Smith, Steve Horvath, Christof Koch, Amanda Ebbert, Andreas Jeromin, Paul Wohnoutka, Michael Hawrylycz, Andy J. Sodt, Beryl Swanson, H. Ronald Zielke, Zackery L. Riley, John A. Morris, Evan T. Lazarz, Chris Abajian, Allan R. Jones, Mike Chapin, Changkyu Lee, Pedro Adolfo Sequeira, Jay Schulkin, Christopher Lau, Jeremy A. Miller, Tim A. Dolbeare, Ling Li, Nick Dee, Sheana Parry, Barry Daly, Patrick D. Parker, Marty Kinnunen, Amy Bernard, Joshua J. Royall, Vance Faber, John G. Hohmann, Patrick R. Hof, Stephen M. Smith, Suvro Datta, Kimberly A. Smith, Elaine H. Shen, Caroline C. Overly, Ed S. Lein, Jayson M. Jochim, Benjamin W. Gregor, Melissa Reding, M. Mallar Chakravarty, Seth G. N. Grant, Lydia Ng, Jimmy Chong, Marquis P. Vawter, Daniel H. Geschwind, David R. Haynor, Andrew F. Boe, Louie N. van de Lagemaat, David R. Fowler
Publikováno v:
Nature, 489(7416), 391-399. Nature Publishing Group
Nature; Vol 489
Nature
Nature; Vol 489
Nature
Neuroanatomically precise, genome-wide maps of transcript distributions are critical resources to complement genomic sequence data and to correlate functional and genetic brain architecture. Here we describe the generation and analysis of a transcrip
Autor:
Tracy Lemon, Tsega Desta, Katie J. Glattfelder, Allan R. Jones, Beth M. Solan, Cathy Copeland, Andrew F. Boe, Jeff Goldy, Ed S. Lein, Chad Soden, Geralyn J. Orta, Michael Hawrylycz, John A. Morris, Darren Bertagnolli, John G. Hohmann, Shanna R. Fischer, Melissa Reding, Sheana Parry, Josh J. Burnell, Kimberly A. Smith, Caroline C. Overly, Jolene Kidney, Owen C. Pearson, Sayan Dev Pathak, Joseph S. Takahashi, Sheila Shapouri, John R. Weller, Emi J. Byrnes, Joshua J. Royall
Publikováno v:
Proceedings of the National Academy of Sciences. 107:19049-19054
Considerable progress has been made in understanding variations in gene sequence and expression level associated with phenotype, yet how genetic diversity translates into complex phenotypic differences remains poorly understood. Here, we examine the
Autor:
Caroline C. Overly, Allan R. Jones
Publikováno v:
Scientific American Mind. 21:56-63
A meticulously constructed atlas of the human brain reveals the molecular roots of mental illness—and of everyday behavior
Autor:
Aneta Czaplinska, Aimee L. Desaki, Maureen P. Howell, Bryan I. Smith, Kevin S. Brockway, Ben J. Duncan, Annabel R. Laramee, Shanna R. Fischer, Tsuey-Ming Chen, Reena Kawal, Nancy Ao, Agnes J. Liang, Amy Bernard, Casey Faber, Ed S. Lein, Geralyn J. Orta, Kevin R. Halverson, Jennifer G. Dougherty, Chinh Dang, Cliff Frensley, Caroline C. Overly, Judith J. Morgan, Murat B. Yaylaoglu, Mark S. Boguski, Lee R. Varnam, Susan M. Sunkin, Crissa K. Wolkey, Amanda Ebbert, Matthew J.A. Wood, Paul Wohnoutka, Benjamin A.C. Facer, Li Chen, Jesse Michaels, James H. Lake, Carey D. Teemer, Rebecca A. Johnson, Axel Visel, Marty Mortrud, Michael Hawrylycz, Christina Thaller, Nerick Mosqueda, Victoria Y. Wong, Tim A. Dolbeare, Xu Feng Yuan, Mei Chi Chin, Marcos J. Ruiz, Carol L. Thompson, Katherine Schaffnit, Theresa A. Zwingman, Sayan Dev Pathak, Tracy Lemon, Lydia Ng, Jimmy Chong, Lili K. Estin, Simon Smith, Rob Young, Kirk D. Larsen, Joshua J. Royall, Randy Ng, Rachel H. Knapik, Mikael Ayres, Nick Dee, Sheana Parry, Ray M. Whitlock, Kenda-Ruth Stumpf, Nadiya V. Shapovalova, Emi J. Byrnes, Taz Sivisay, Matthew R. Hart, Chihchau L. Kuan, Owen C. Pearson, Ellen Diep, Nadia R. Sarno, Madhavi Sutram, Andrew F. Boe, Clifford R. Slaughterbeck, Zackery L. Riley, Rebecca J. Morgan, Hong-Wei Dong, Tsega Desta, Patrick T. Karr, Andy J. Sodt, John G. Hohmann, Suvro Datta, Stephen A. Rowland, Tu H. Pak, Ralph B. Puchalski, Lin Chen, Nick N. Stewart, Ying Liu, Hannah R. Rockett, Brian L. Youngstrom, Darren P. Jeung, Lon T. Luong, Matthew J. Donelan, Amy Bensinger, Katie J. Glattfelder, Bin Zhang, Allan R. Jones, Gregor Eichele, Rick Fields, Sabrina N. Gates, Kimberly A. Smith, Angelene Tam, Brian E. Crook, Tim P. Fliss, Jolene Kidney, Christopher Lau
Publikováno v:
Nature. 445:168-176
Molecular approaches to understanding the functional circuitry of the nervous system promise new insights into the relationship between genes, brain and behaviour. The cellular diversity of the brain necessitates a cellular resolution approach toward
Autor:
Caroline C. Overly, Frances M. Lucy, Ian McFarlane, Kieran C. Breen, Lisa McConlogue, Angela M. Gillian
Publikováno v:
Journal of Neuroscience Research. 49:154-160
The amyloid beta precursor protein (AbetaPP) can exist as a membrane-bound glycoprotein which modulates neural cell adhesion. The adhesion of clones of the AtT20 mouse pituitary cell line, transfected with cDNA coding for the 695 (AbetaPP695) and 751
Publikováno v:
The Journal of Neuroscience. 16:6056-6064
Despite the wealth of information about endocytic pathways in non-neuronal cells, little is known about these crucial sorting, recycling, and degradative pathways in neurons. In this report, we analyzed in detail the dynamic steady-state organization
Publikováno v:
Journal of Cell Science. 109:971-980
Regional regulation of organelle transport seems likely to play an important role in establishing and maintaining distinct axonal and dendritic domains in neurons, and in managing differences in local metabolic demands. In addition, known differences
Publikováno v:
Proceedings of the National Academy of Sciences. 92:3156-3160
Organelle acidification is an essential element of the endosomal-lysosomal pathway, but our understanding of the mechanisms underlying progression through this pathway has been hindered by the absence of adequate methods for quantifying intraorganell