Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Caroline C Whitacre"'
Autor:
Kim A. Campbell, Caroline C. Whitacre
Publikováno v:
Infection, Resistance, and Immunity ISBN: 9780203750964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1651376fdd74cec5026f3b3fa8050bf3
https://doi.org/10.1201/9780203750964-10
https://doi.org/10.1201/9780203750964-10
Autor:
Bruce F Bebo, Mark Allegretta, Douglas Landsman, Kathy M Zackowski, Fiona Brabazon, Walter A Kostich, Timothy Coetzee, Alexander Victor Ng, Ruth Ann Marrie, Kelly R Monk, Amit Bar-Or, Caroline C Whitacre
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 28(3)
Background: Multiple Sclerosis (MS) is a growing global health challenge affecting nearly 3 million people. Progress has been made in the understanding and treatment of MS over the last several decades, but cures remain elusive. The National MS Socie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de86a82bff80f9436d2b160b2b286637
https://pubmed.ncbi.nlm.nih.gov/35236198
https://pubmed.ncbi.nlm.nih.gov/35236198
Autor:
Tracey L. Papenfuss, J. Cameron Thrash, Patricia E. Danielson, Pamela E. Foye, Brian S. Hllbrush, J. Gregor Sutcliffe, Caroline C. Whitacre, Monica J. Carson
Publikováno v:
The Scientific World Journal, Vol 7, Pp 112-120 (2007)
Microglia are the tissue macrophages of the CNS. Microglial activation coupled with macrophage infiltration is a common feature of many classic neurodegenerative disorders. The absence of cell-type specific markers has confounded and complicated the
Externí odkaz:
https://doaj.org/article/591e5862f31c4ab799026b7616ae5ab9
Autor:
Jonathan P. Godbout, Ashley M. Fenn, Mireia Guerau-de-Arellano, Kristen Smith, Amy E. Lovett-Racke, Caroline C. Whitacre
Publikováno v:
Neurobiology of Aging. 34:2748-2758
Microglia develop an inflammatory phenotype during normal aging. The mechanism by which this occurs is not well understood, but might be related to impairments in several key immunoregulatory systems. Here we show that micro-RNA (miR)-29a and miR-29b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82fec9b1422ff4f2a68d93b61d5e0da0
https://doi.org/10.1016/j.neurobiolaging.2013.06.007
https://doi.org/10.1016/j.neurobiolaging.2013.06.007
Serum exosomes in pregnancy-associated immune modulation and neuroprotection during CNS autoimmunity
Autor:
Dana M. McTigue, Jessica Williams, Akshata Almad, Kristen Smith, Na Tosha N. Gatson, Caroline C. Whitacre
Publikováno v:
Clinical Immunology. 149:236-243
In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), relapses are markedly reduced during pregnancy. Exosomes are lipid-bound vesicles and are more abundant in the serum during pregnancy. Using murine EAE, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb201c9d3c63cc6e58b547ba0ae5c63
https://doi.org/10.1016/j.clim.2013.04.005
https://doi.org/10.1016/j.clim.2013.04.005
Autor:
Yi Zhang, Todd Shawler, Alexander G. Rabchevsky, Nicole D. Powell, Caroline C. Whitacre, Mark S. Nash, Jonathan Wells, Anna Bratasz, Brenda F. Reader, Shweta Mandrekar-Colucci, John F. Sheridan, Zachary M. Weil, Zhen Guan, Kun Huang, Phillip G. Popovich
Publikováno v:
Journal of Neuroscience. 33:12970-12981
Autonomic dysreflexia (AD), a potentially dangerous complication of high-level spinal cord injury (SCI) characterized by exaggerated activation of spinal autonomic (sympathetic) reflexes, can cause pulmonary embolism, stroke, and, in severe cases, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd9a1bc4f5bc5eadf85c8ec8bc5c448
https://doi.org/10.1523/jneurosci.1974-13.2013
https://doi.org/10.1523/jneurosci.1974-13.2013
Autor:
Sanjay Varikuti, Caroline C. Whitacre, Arlene H. Sharpe, Ran Dong, Steve Oghumu, Todd Shawler, Abhay R. Satoskar, Brian M. M. Ahmer, Cesar Terrazas, Claudio M. Lezama-Davila, Sanjay Rajagopalan, Thomas Kampfrath, Richard M. Locksley
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 190, iss 5
CXCR3, expressed mainly on activated T and NK cells, is implicated in a host of immunological conditions and can contribute either to disease resolution or pathology. We report the generation and characterization of a novel CXCR3 internal ribosome en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89449dd75bf3013403c4ded5d0cd0bc9
https://doi.org/10.4049/jimmunol.1201170
https://doi.org/10.4049/jimmunol.1201170
Autor:
Abhay R. Satoskar, Stefan Costinean, Carlo M. Croce, Kristen Smith, Michael K. Racke, Caroline C. Whitacre, Amy E. Lovett-Racke, Arianna Bottoni, Mireia Guerau-de-Arellano, Jessica Williams, Gina Mavrikis Cox
Publikováno v:
The Journal of Immunology. 189:1567-1576
Th cell programming and function is tightly regulated by complex biological networks to prevent excessive inflammatory responses and autoimmune disease. The importance of microRNAs (miRNAs) in this process is highlighted by the preferential Th1 polar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b92ceea5e84648d72133def72f103e00
https://doi.org/10.4049/jimmunol.1103171
https://doi.org/10.4049/jimmunol.1103171
Autor:
Sanjay Varikuti, Stephanie Seveau, Steve Oghumu, Caroline C. Whitacre, Hannah E. Cummings, Anasuya Sarkar, Mark D. Wewers, Patrick K. Reville, Danuta Radzioch, Abhay R. Satoskar, Nicholas Zorko, Thomas Rückle, Joseph Barbi, Claudio M. Lezama-Davila, Tracy L. Keiser, Bao Lu, Christian Rommel
Publikováno v:
Proceedings of the National Academy of Sciences. 109:1251-1256
Obligate intracellular pathogens such as Leishmania specifically target host phagocytes for survival and replication. Phosphoinositide 3-kinase γ (PI3Kγ), a member of the class I PI3Ks that is highly expressed by leukocytes, controls cell migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e344cedb22634cc44d4b7f33fc47b199
https://doi.org/10.1073/pnas.1110339109
https://doi.org/10.1073/pnas.1110339109
Autor:
Ryan C. Winger, Michael K. Racke, Jakub Godlewski, Caroline C. Whitacre, Sean E. Lawler, Kristen Smith, Amy E. Lovett-Racke, Yue Liu, Mireia Guerau-de-Arellano
Publikováno v:
Brain. 134:3578-3589
Pro-inflammatory T cells mediate autoimmune demyelination in multiple sclerosis. However, the factors driving their development and multiple sclerosis susceptibility are incompletely understood. We investigated how micro-RNAs, newly described as post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e216663917518492fb9b3495a0bb4f
https://doi.org/10.1093/brain/awr262
https://doi.org/10.1093/brain/awr262