Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Caroline Bull Melsom"'
Autor:
Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218110 (2019)
PurposeWe previously reported that inhibitory G protein (Gi) exerts intrinsic receptor-independent inhibitory activity upon adenylyl cyclase (AC) that regulates contractile force in rat ventricle. The two major subtypes of AC in the heart are AC5 and
Externí odkaz:
https://doaj.org/article/79ca3f0a931a43d6af8fdd3172083fc6
Autor:
Caroline Bull Melsom, Øivind Ørstavik, Jan-Bjørn Osnes, Tor Skomedal, Finn Olav Levy, Kurt Allen Krobert
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106608 (2014)
BACKGROUND AND PURPOSE: Despite the view that only β2- as opposed to β1-adrenoceptors (βARs) couple to G(i), some data indicate that the β1AR-evoked inotropic response is also influenced by the inhibition of Gi. Therefore, we wanted to determine
Externí odkaz:
https://doaj.org/article/ec8af9fb309a4115810c827c74202880
Autor:
Viacheslav O. Nikolaev, Caroline Bull Melsom, H. Kirk Hammond, Tor Skomedal, Finn Olav Levy, Marie-Victoire Cosson, Kurt A. Krobert, Jan-Bjørn Osnes, Øivind Ørstavik, Ngai Chin Lai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0218110 (2019)
PLoS ONE, Vol 14, Iss 6, p e0218110 (2019)
PurposeWe previously reported that inhibitory G protein (Gi) exerts intrinsic receptor-independent inhibitory activity upon adenylyl cyclase (AC) that regulates contractile force in rat ventricle. The two major subtypes of AC in the heart are AC5 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96ced523d61a1410efaefb08eda32f9
http://hdl.handle.net/10852/74414
http://hdl.handle.net/10852/74414
Autor:
Ivar Sjaastad, Kurt A. Krobert, Jan Magnus Aronsen, Øivind Ørstavik, Finn Olav Levy, R.I. Hussain, Caroline Bull Melsom, Jan-Bjørn Osnes, Tor Skomedal
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 387:1177-1186
Studies suggest that increased activity of Gi contributes to the reduced β-adrenoceptor-mediated inotropic response (βAR-IR) in failing cardiomyocytes and that β2AR-IR but not β1AR-IR is blunted by dual coupling to Gs and Gi. We aimed to clarify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82221af3e60f7d486d2099a5022f21c
https://doi.org/10.1007/s00210-014-1036-7
https://doi.org/10.1007/s00210-014-1036-7
Autor:
Øivind Ørstavik, Tor Skomedal, Kurt A. Krobert, Finn Olav Levy, Caroline Bull Melsom, Jan-Bjørn Osnes
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106608 (2014)
PLoS ONE
PLoS ONE
BACKGROUND AND PURPOSE: Despite the view that only β2- as opposed to β1-adrenoceptors (βARs) couple to G(i), some data indicate that the β1AR-evoked inotropic response is also influenced by the inhibition of Gi. Therefore, we wanted to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a842b9b9cada9acb4bcfdc70616866a
http://hdl.handle.net/10852/47899
http://hdl.handle.net/10852/47899
Publikováno v:
Frontiers in Neuroinformatics. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92b695cd5ba7e1098801923e1ca1ec5
https://doi.org/10.3389/conf.neuro.11.2009.08.027
https://doi.org/10.3389/conf.neuro.11.2009.08.027