Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Caroline Bull"'
Autor:
Hannah Compton, Madeleine L. Smith, Caroline Bull, Roxanna Korologou-Linden, Yoav Ben-Shlomo, Joshua A. Bell, Dylan M. Williams, Emma L. Anderson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Mechanisms through which most known Alzheimer’s disease (AD) loci operate to increase AD risk remain unclear. Although Apolipoprotein E (APOE) is known to regulate lipid homeostasis, the effects of broader AD genetic liability on non-lipid
Externí odkaz:
https://doaj.org/article/c4e9dfc97f9f459e87c12d60e4dc53dd
Autor:
Caroline Bull, Emma Hazelwood, Joshua A Bell, Vanessa Tan, Andrei-Emil Constantinescu, Carolina Borges, Danny Legge, Kimberley Burrows, Jeroen R Huyghe, Hermann Brenner, Sergi Castellvi-Bel, Andrew T Chan, Sun-Seog Kweon, Loic Le Marchand, Li Li, Iona Cheng, Rish K Pai, Jane C Figueiredo, Neil Murphy, Marc J Gunter, Nicholas J Timpson, Emma E Vincent
Publikováno v:
eLife, Vol 12 (2023)
Background: Recognizing the early signs of cancer risk is vital for informing prevention, early detection, and survival. Methods: To investigate whether changes in circulating metabolites characterize the early stages of colorectal cancer (CRC) devel
Externí odkaz:
https://doaj.org/article/0ffb1e6001ab4bd0a21592a96abed076
Autor:
Mark Gormley, Tom Dudding, Steven J Thomas, Jessica Tyrrell, Andrew R Ness, Miranda Pring, Danny Legge, George Davey Smith, Rebecca C Richmond, Emma E Vincent, Caroline Bull
Publikováno v:
eLife, Vol 12 (2023)
A recent World Health Organization report states that at least 40% of all cancer cases may be preventable, with smoking, alcohol consumption, and obesity identified as three of the most important modifiable lifestyle factors. Given the significant de
Externí odkaz:
https://doaj.org/article/84d346a026074e03b51ebc14cd603507
Autor:
Susan Martin, Jessica Tyrrell, E Louise Thomas, Matthew J Bown, Andrew R Wood, Robin N Beaumont, Lam C Tsoi, Philip E Stuart, James T Elder, Philip Law, Richard Houlston, Christopher Kabrhel, Nikos Papadimitriou, Marc Gunter, Caroline Bull, Joshua A Bell, Emma E Vincent, Naveed Sattar, Malcolm G Dunlop, Ian PM Tomlinson, Sara Lindström, INVENT consortium, Jimmy D Bell, Timothy Frayling, Hanieh Yaghootkar
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/40b858df13344706935722cd933d8d45
Autor:
Caroline Bull, Damien Belobrajdic, Sara Hamzelou, Darren Jones, Wayne Leifert, Rocío Ponce-Reyes, Netsanet Shiferaw Terefe, Gemma Williams, Michelle Colgrave
Publikováno v:
Foods, Vol 11, Iss 4, p 528 (2022)
Future food security for healthy populations requires the development of safe, sustainably-produced protein foods to complement traditional dietary protein sources. To meet this need, a broad range of non-traditional protein foods are under active in
Externí odkaz:
https://doaj.org/article/40c26942531d4da39dbec2b79fdaf8d1
Autor:
Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218110 (2019)
PurposeWe previously reported that inhibitory G protein (Gi) exerts intrinsic receptor-independent inhibitory activity upon adenylyl cyclase (AC) that regulates contractile force in rat ventricle. The two major subtypes of AC in the heart are AC5 and
Externí odkaz:
https://doaj.org/article/79ca3f0a931a43d6af8fdd3172083fc6
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119367 (2015)
Chronic psychological stress and nutritional deficiencies are factors that impact negatively on human health and disease risk. Chronic stress has been associated with accelerated leukocyte telomere shortening in numerous cohorts, however, a mechanist
Externí odkaz:
https://doaj.org/article/fed62b9c9ec64952931cb373ccbcfa26
Autor:
Caroline Bull Melsom, Øivind Ørstavik, Jan-Bjørn Osnes, Tor Skomedal, Finn Olav Levy, Kurt Allen Krobert
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106608 (2014)
BACKGROUND AND PURPOSE: Despite the view that only β2- as opposed to β1-adrenoceptors (βARs) couple to G(i), some data indicate that the β1AR-evoked inotropic response is also influenced by the inhibition of Gi. Therefore, we wanted to determine
Externí odkaz:
https://doaj.org/article/ec8af9fb309a4115810c827c74202880
Autor:
Mark Gormley, Tom Dudding, Steven J Thomas, Jessica Tyrrell, Andrew R Ness, Miranda Pring, Danny Legge, George Davey Smith, Rebecca C Richmond, Emma E Vincent, Caroline Bull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0c6426fddd635ed9c114d065bbb247
https://doi.org/10.7554/elife.82674.sa2
https://doi.org/10.7554/elife.82674.sa2
Autor:
Mark Gormley, Tom Dudding, Steven J Thomas, Jessica Tyrrell, Andrew R Ness, Miranda Pring, Danny Legge, George Davey Smith, Rebecca C Richmond, Emma E Vincent, Caroline Bull
A recent World Health Organization report states that at least 40% of all cancer cases may be preventable, with smoking, alcohol consumption, and obesity identified as three of the most important modifiable lifestyle factors. Given the significant de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc0ae64a61b10a76f6c34c81b99d455
https://doi.org/10.1101/2022.08.10.22278617
https://doi.org/10.1101/2022.08.10.22278617