Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Caroline Bonnel"'
Autor:
Margaret Farias, Kiara Bianchi, Carter Atkinson, Donna Ohora, Ann Txakeeyang, Caroline Bonnel, Susan Jarvi
Publikováno v:
The Journal of Immunology. 190:125.11-125.11
A better understanding of host defenses against malaria is important, but most studies have traditionally focused on resistance and/or immunological mechanisms that limit parasite burden. Host tolerance mechanisms are thought to minimize physiologica
Publikováno v:
The Journal of Immunology. 190:119.17-119.17
Vaccine efficacy declines significantly with age, yet old baboons immunized with Yersinia pestis LcrV antigen generated vigorous humoral responses [JI 181:109 (2008)] while aged rhesus macaques did not. To assess whether these non-human primate (NHP)
Publikováno v:
The Journal of Immunology. 188:166.24-166.24
The ability to mount effective immune responses declines with age, which correlates clinically with decreased vaccine efficacy and increased susceptibility to infection and cancer. As a result, new vaccines should be tested for efficacy in older indi