Výsledky vyhledávání - "Caroline Baer"

Akademický článek

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

Autor: Mario Leonardo Squadrito, Caroline Baer, Frédéric Burdet, Claudio Maderna, Gregor D. Gilfillan, Robert Lyle, Mark Ibberson, Michele De Palma

Publikováno v: Cell Reports, Vol 8, Iss 5, Pp 1432-1446 (2014)

MicroRNA (miRNA) transfer via exosomes may mediate cell-to-cell communication. Interestingly, specific miRNAs are enriched in exosomes in a cell-type-dependent fashion. However, the mechanisms whereby miRNAs are sorted to exosomes and the significanc

Externí odkaz: https://doaj.org/article/69853ee0a9164b968311d9288464bf31

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Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

Autor: Aditya Bardia, Lore Lambein, Rakesh K. Jain, Simon Tazzyman, Lisa M. Coussens, Mario Leonardo Squadrito, Laura Spring, Ioanna Keklikoglou, Alan Guichard, Claire E. Lewis, Michele De Palma, Chiara Cianciaruso, Jeffrey W. Pollard, Esra Güç, Antonino M. Cassarà, Gino B. Ferraro, M. Luisa Iruela-Arispe, Caroline Baer, Amanda Poissonnier

Publikováno v: Keklikoglou, I, Cianciaruso, C, Guc, E, Squadrito, M L, Spring, L M, Tazzyman, S, Lambein, L, Poissonnier, A, Ferraro, G B, Baer, C, Cassara, A, Guichard, A, Iruela-Arispe, M L, Lewis, C E, Coussens, L M, Bardia, A, Jain, R K, Pollard, J W & De Palma, M 2019, ' Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models ', Nature Cell Biology, vol. 21, no. 2, pp. 190–202 . https://doi.org/10.1038/s41556-018-0256-3
Nature Cell Biology

Cytotoxic chemotherapy is an effective treatment for invasive breast cancer. However, experimental studies in mice also suggest that chemotherapy has pro-metastatic effects. Primary tumours release extracellular vesicles (EVs), including exosomes, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a174dddce8c60225342213d9add0b61
https://doi.org/10.1038/s41556-018-0256-3

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Akademický článek

Morale in a Trade-Union

Autor: Rose, Caroline Baer

Publikováno v: American Journal of Sociology, 1950 Sep 01. 56(2), 167-174.

Externí odkaz: https://www.jstor.org/stable/2772166

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SAT-713 Novel Estrogenic Gene Regulation Induced by OTC Medications Containing Paraben Preservatives Is Dependent on Concentration that Varies Between Products and Batches

Autor: Elena Skripnikova, Thomas E. Wiese, Emily Ragland, Peng Ma, Changde Zhang, Caroline Baer

Publikováno v: Journal of the Endocrine Society

Methylparaben, ethylparaben, and propylparaben are widely used as preservatives in food products, cosmetics, and pharmaceuticals. Parabens have been shown to be weak estrogens and this laboratory has described that extracts of some over the counter (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa12fbab09334aad93880140b7efbd6
https://doi.org/10.1210/jendso/bvaa046.1267

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MON-033 Evaluating the Estrogen Activity of OTC Products Containing Parabens

Autor: Thomas E. Wiese, Peng Ma, Caroline Baer, Emily Ragland

Publikováno v: Journal of the Endocrine Society

Parabens such as methylparaben, ethylparaben, and propylparaben are widely used in food products, cosmetics, and pharmaceuticals as preservatives. Many products contain multiple parabens to enhance the preservative effect. Parabens have been shown to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da038026b8027a9cacb209c5609d6b02
https://doi.org/10.1210/js.2019-mon-033

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Perivascular Macrophages Limit Permeability

Autor: Esra Güç, Safiyyah Ziyad, Michele De Palma, Ryan D. Freshman, Mario Leonardo Squadrito, Julia J. Mack, Witold W. Kilarski, Huanhuan He, Caroline Baer, Carmen M. Warren, M. Luisa Iruela-Arispe, Austin I. McDonald, Melody A. Swartz

Publikováno v: He, H; Mack, JJ; Güç, E; Warren, CM; Squadrito, ML; Kilarski, WW; et al.(2016). Perivascular Macrophages Limit Permeability. Arteriosclerosis, Thrombosis, and Vascular Biology, 36(11), 2203-2212. doi: 10.1161/ATVBAHA.116.307592. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2mq001hp
Arteriosclerosis, thrombosis, and vascular biology, vol 36, iss 11
Arteriosclerosis thrombosis and vascular biology

Objective— Perivascular cells, including pericytes, macrophages, smooth muscle cells, and other specialized cell types, like podocytes, participate in various aspects of vascular function. However, aside from the well-established roles of smooth mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4a0cecc02c5d6dd6cc2d3bf16037dd
https://doi.org/10.1161/atvbaha.116.307592

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Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity

Autor: Carola Ries, Danielle Thompson, Sabine Hoves, Sarah K. Hansen, Michele De Palma, Mario Leonardo Squadrito, Caroline Baer, Anna Kiialainen, Chia Huey Ooi, Damya Laoui

Publikováno v: Nature Cell Biology

Tumour-associated macrophages (TAMs) largely express an alternatively activated (or M2) phenotype, which entails immunosuppressive and tumour-promoting capabilities. Reprogramming TAMs towards a classically activated (M1) phenotype may thwart tumour-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2c6e5a24e433e00283139fc5b705b
https://doi.org/10.1038/ncb3371

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Correction: restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP

Publikováno v: Cancer Cell. 30(5)

SummaryNearly 90% of human melanomas contain inactivated wild-type p53, the underlying mechanisms for which are not fully understood. Here, we identify that cyclin B1/CDK1-phosphorylates iASPP, which leads to the inhibition of iASPP dimerization, pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27a17f664a1c5d1c0ef72d60a3f2d1c
http://ora.ox.ac.uk/objects/uuid:

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Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB

Autor: Wenjie Ge, Elizabeth A. Slee, Zinaida Dedeić, Gopinath Sutendra, Caroline Baer, Xingwen Wang, Kunming Zhao, Ying Hu, Xin Lu

Publikováno v: Oncotarget

An intriguing biological question relating to cell signaling is how the inflammatory mediator NF-kB and the tumour suppressor protein p53 can be induced by similar triggers, like DNA damage or infection, yet have seemingly opposing or sometimes coope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1b3673330e9d1c51f5782bf9d06d05
http://ora.ox.ac.uk/objects/uuid:81f7754a-47f5-4d3d-87a0-e118bd963b4b

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Morale in a Trade-Union

Autor: Caroline Baer Rose

Publikováno v: American Journal of Sociology. 56:167-174

This is a study of morale in a large CIO industrial union the Midwest. A questionnaire asking about specific shop situations was given to forty-five students in a worker's education class. Low morale was indicated by failure to believe that economic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::726335c3283f12f136fdaf8f0f2f10f3
https://doi.org/10.1086/220699

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