Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Caroline B. Morehouse"'
Autor:
Caroline B. Morehouse, Nisc Comparative Sequencing Program, James W. Thomas, Robert T. Sullivan
Publikováno v:
Nucleic Acids Research
Cross-species sequence comparisons are a prominent method for analyzing genomic DNA and an ever increasing number of species are being selected for whole-genome sequencing. Targeted comparative genomic sequencing is a complementary approach to whole-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9065057339eb70380c3beabdf95d58
https://doi.org/10.1093/nar/gkn293
https://doi.org/10.1093/nar/gkn293
A Genotyping Assay to Determine Plumage Morph in The White-Throated Sparrow (Zonotrichia Albicollis)
Publikováno v:
The Auk. 124:1330-1335
In alternate plumage, the White-throated Sparrow (Zonotrichia albicollis) is polymorphic, such that individuals exhibit a median crown stripe that is either white or tan in color. This plumage polymorphism is believed to be caused by a chromosomal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3c3bba51483ae6b7a837872bb05bf8
https://doi.org/10.1093/auk/124.4.1330
https://doi.org/10.1093/auk/124.4.1330
Autor:
Suzanne J. Senior, James D. Douglas, Caroline B. Morehouse, David E. Minnikin, Benjawan Phetsukiri, Ian B. Campbell, Gurdyal S. Besra
Publikováno v:
Microbiology. 148:3101-3109
Analogues of the antibiotic thiolactomycin (TLM) have been synthesized and have been shown to have enhanced activity against whole cells of Mycobacterium tuberculosis H37Rv and against mycolic acid biosynthesis in cell extracts of Mycobacterium smegm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36c260d0b1c9681f2eb976f2fdaf701
https://doi.org/10.1099/00221287-148-10-3101
https://doi.org/10.1099/00221287-148-10-3101
Autor:
Michael R. McNeil, Lynn G. Dover, Caroline B. Morehouse, Laurent Kremer, Howard R. Morris, Patrick J. Brennan, Paul Hitchin, Gurdyal S. Besra, Ken Duncan, Christopher Flaherty, A. Dell, Martin J. Everett
Publikováno v:
Journal of Biological Chemistry. 276:26430-26440
The cell wall of Mycobacterium tuberculosis and related genera is unique among prokaryotes, consisting of a covalently bound complex of mycolic acids, D-arabinan and D-galactan, which is linked to peptidoglycan via a special linkage unit consisting o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd5e07df464a00643d05d3e769808dc
https://doi.org/10.1074/jbc.m102022200
https://doi.org/10.1074/jbc.m102022200
Autor:
James D. Douglas, Caroline B. Morehouse, Laurent Kremer, Lynn G. Dover, David Alland, Gurdyal S. Besra, Alain R. Baulard, Jeremy H. Lakey, William R. Jacobs, Mark R. Guy, David E. Minnikin, Patrick J. Brennan
Publikováno v:
Journal of Biological Chemistry. 275:16857-16864
Prevention efforts and control of tuberculosis are seriously hampered by the appearance of multidrug-resistant strains of Mycobacterium tuberculosis, dictating new approaches to the treatment of the disease. Thiolactomycin (TLM) is a unique thiolacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ae4b390b58b177ea7e84116a6d4a8a
https://doi.org/10.1074/jbc.m000569200
https://doi.org/10.1074/jbc.m000569200
Autor:
Gurdyal S. Besra, Robert C. Reynolds, Caroline B. Morehouse, Joseph A. Maddry, Ashish K. Pathak, William J. Suling, Dean C. Crick
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:2407-2413
The biochemically unique structures of sugar residues in the outer cell wall of Mycobacterium tuberculosis (MTB) make the pathways for their biosynthesis and utilization attractive targets for the development of new and selective anti-tubercular agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f9c914525a2c124a838d03098c9b03
https://doi.org/10.1016/s0968-0896(99)00199-6
https://doi.org/10.1016/s0968-0896(99)00199-6
Autor:
Patrick J. Brennan, Caroline B. Morehouse, Gurdyal S. Besra, Christian M. Rittner, Charles J. Waechter
Publikováno v:
Journal of Biological Chemistry. 272:18460-18466
The mycobacterial lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), are potent immunomodulators in tuberculosis and leprosy. Little is known of their biosynthesis, other than being based on phosphatidylinositol (PI), and they probably origina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c0a7a18238107cf9b1fc50920460fb
https://doi.org/10.1074/jbc.272.29.18460
https://doi.org/10.1074/jbc.272.29.18460
Autor:
Erin L. Baldwin, Caroline B. Morehouse, James W. Thomas, Christa Lese Martin, Mario Cáceres, Donna L. Maney, Meghan E. Short, Joshua J. Lowman
Publikováno v:
Genetics. 179(3)
Variation in social behavior and plumage in the white-throated sparrow (Zonotrichia albicollis) is linked to an inversion polymorphism on chromosome 2. Here we report the results of our comparative cytogenetic mapping efforts and population genetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93aa3646988000bc0b9e0f4293aaa8
https://pubmed.ncbi.nlm.nih.gov/18562641
https://pubmed.ncbi.nlm.nih.gov/18562641
Autor:
Juma'a R. Al Dulayymi, Patrick J. Brennan, Mark S. Baird, Caroline B. Morehouse, Geoffrey D. Coxon, Gurdyal S. Besra, David E. Minnikin
Publikováno v:
Chemistry and physics of lipids. 127(1)
A 23-26-carbon chain length range of omega-19 (1'R,2'S) cyclopropane fatty acids, related to mycobacterial mycolic acids, has been prepared. The key cyclopropyl intermediate, (1'R,2'S)-(Z)-1-formyl-2-octadecylcyclopropane, underwent Wittig chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deb01671b954d7cd73c1f7f07c07acc
https://pubmed.ncbi.nlm.nih.gov/14706739
https://pubmed.ncbi.nlm.nih.gov/14706739
Autor:
Ashish K. Pathak, Robert C. Reynolds, Vibha Pathak, Sudagar S Gurcha, Joseph A. Maddry, Gurdyal S. Besra, Caroline B. Morehouse, William J. Suling
Publikováno v:
Bioorganicmedicinal chemistry. 10(4)
The mycobacterial cell wall is a potential target for new drug development. Herein we report the preparation and activity of several n -octyl-5-(α- d -arabinofuranosyl)-β- d -galactofuranoside derivatives. A cell-free assay system has been utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88656c0ffc1a73e17513ef3f7d01237c
https://pubmed.ncbi.nlm.nih.gov/11836099
https://pubmed.ncbi.nlm.nih.gov/11836099