Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Caroline B. Marshall"'
Autor:
Rohan S. Balkawade, Caroline B. Marshall, Michael R. Crowley, Jill W. Verlander, Chao Chen, David K. Crossman, William L. Clapp
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F1026-F1040
Conditional gene targeting using Cre recombinase has offered a powerful tool to modify gene function precisely in defined cells/tissues and at specific times. However, in mammalian cells, Cre recombinase can be genotoxic. The importance of including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492950cacc6aa22ab3b7c1039bb21842
https://doi.org/10.1152/ajprenal.00359.2018
https://doi.org/10.1152/ajprenal.00359.2018
Autor:
Caroline B. Marshall, Camille Macé, Sumant S. Chugh, Maria Del Nogal Avila, Lionel C. Clement
Publikováno v:
Translational Research. 165:499-504
The development of new and specific treatment options for kidney disease in general and glomerular diseases in specific has lagged behind other fields like heart disease and cancer. As a result, nephrologists have had to test and adapt therapeutics d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0b5f27adec04ff138f3801d394c988
https://doi.org/10.1016/j.trsl.2014.06.004
https://doi.org/10.1016/j.trsl.2014.06.004
Autor:
Caroline B. Marshall
Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in the United States and is a major cause of cardiovascular disease and death. DN develops insidiously over a span of years before clinical manifestations, including microalbumi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb37d3f42b2bd99d56454b60a0f08df0
https://europepmc.org/articles/PMC6121820/
https://europepmc.org/articles/PMC6121820/
Autor:
Caroline B. Marshall, Camille Macé, Hector Donoro-Blazquez, María del Nogal-Avila, Lionel C. Clement, Sumant S. Chugh, Manish K. Saha
Improved understanding of glomerular disease mechanisms over the past decade has led to the emergence of new and targeted therapeutic strategies for chronic kidney disease (CKD). Most promising among these are the administration of recombinant mutate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e35718092ba9eea3cd88579e52bfb98
https://europepmc.org/articles/PMC4967169/
https://europepmc.org/articles/PMC4967169/
Autor:
Caroline B. Marshall, Francis Kim, Jolanta Kowalewska, Robert Feil, Ron Krofft, Christine M. Logar, Mary Blonski, Jeffrey W. Pippin, Stuart J. Shankland, Charles E. Alpers
Publikováno v:
American Journal of Physiology-Renal Physiology. 300:F1026-F1042
Podocytes are considered terminally differentiated cells in the mature kidney under normal conditions. In the face of injury, podocytes may proceed along several possible pathways, including dedifferentiation and proliferation, persistent cell cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e13a923b489af53157908ea6e747446
https://doi.org/10.1152/ajprenal.00187.2010
https://doi.org/10.1152/ajprenal.00187.2010
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1140-F1151
In response to injury, the highly specialized and terminally differentiated glomerular visceral epithelial cell, or podocyte, may undergo several cell fates, including dedifferentiation and proliferation, persistent cell cycle arrest, hypertrophy, ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e957808811f2c8263027c9bc2fab1d
https://doi.org/10.1152/ajprenal.00216.2009
https://doi.org/10.1152/ajprenal.00216.2009
Autor:
Takamoto Ohse, Kelly L. Hudkins, Jeffrey B. Kopp, Ronald D. Krofft, Caroline B. Marshall, Jeffrey W. Pippin, Michael R. Vaughan, Charles E. Alpers, Alice M. Chang, Stuart J. Shankland
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F702-F711
Studies have shown that certain cells of the glomerular tuft begin to express proteins considered unique to other cell types upon injury. Little is known about the response of parietal epithelial cells (PEC) to injury. To determine whether PECs chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98225d5487f72bc97df647bc527da590
https://doi.org/10.1152/ajprenal.00428.2009
https://doi.org/10.1152/ajprenal.00428.2009
Publikováno v:
Nephron Experimental Nephrology. 102:e39-e48
Globally, glomerular diseases are a leading cause of chronic and end-stage renal disease. In the mature glomerulus, under normal conditions, glomerular cells have a low turnover rate. However, in disease, a variety of pathophysiological stimuli can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca6d866ad6aba4bdc6ff008b5227786
https://doi.org/10.1159/000088400
https://doi.org/10.1159/000088400
Publikováno v:
Journal of the American Society of Nephrology. 16:2615-2625
Nephrotic-range proteinuria is due to glomerular diseases characterized by podocyte injury. Glucocorticoids are the standard of care for most forms of nephrotic syndrome. However, the precise mechanisms underlying the beneficial effects of glucocorti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f21212d0d8229f13cebc7185898a89
https://doi.org/10.1681/asn.2005020142
https://doi.org/10.1681/asn.2005020142
Autor:
Caroline B. Marshall, Lionel C. Clement, Carmen Avila Casado, Maria Del Nogal Avila, Sumant S. Chugh, Camille Macé, Hector Donoro Blazquez
Publikováno v:
Nephrology Dialysis Transplantation. 32:iii445-iii445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc897a9764d67ebb30770e4a197d368c
https://doi.org/10.1093/ndt/gfx162.mp053
https://doi.org/10.1093/ndt/gfx162.mp053