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pro vyhledávání: '"Caroline Anne Cuoco"'
Autor:
Charles David Weaver, Emily Days, Craig W. Lindsley, Alice L. Rodriguez, Paige N. Vinson, Colleen M. Niswender, Anna L. Blobaum, Matthew T. Loch, Caroline Anne Cuoco, P.J. Conn, Krystian A. Kozek, Mark G. Fulton
Publikováno v:
Letters in Drug Design & Discovery
Background: This article describes the challenges in the discovery and optimization of mGlu2/4 heterodimer Positive Allosteric Modulators (PAMs). Methods: Initial forays based on VU0155041, a PAM of both the mGlu4 homodimer and the mGlu2/4 heterodime