Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts

Autor: Epie Boven, Kasper van der Born, Godefridus J. Peters, Irene H.L. Hamelers, Caroline A.M. Erkelens, Rutger W.H.M. Staffhorst, Anton I.P.M. de Kroon

Publikováno v: Staffhorst, R W, van der Born, K, Erkelens, CA, Hamelers, I H, Peters, G J, Boven, E & de Kroon, A I 2008, ' Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts ', Anti-Cancer Drugs, vol. 19, no. 7, pp. 721-727 . https://doi.org/10.1097/CAD.0b013e328304355f
Anti-Cancer Drugs, 19(7), 721-727. Lippincott Williams and Wilkins

Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloridoplatinum(II) (cisplatin), characterized by an unprecedented cisplatin-to-lipid molar ratio, and exhibiting strongly increased in-vitro cytotoxicit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c797703845190c6b85ccfb9af83fdc
https://doi.org/10.1097/cad.0b013e328304355f

Superior efficacy of trimelamol to hexamethylmelamine in human ovarian cancer xenografts

Autor: Epie Boven, Hennie M.M. Schlüper, Maria M. Nauta, Caroline A.M. Erkelens, Herbert M. Pinedo

Publikováno v: Cancer Chemotherapy and Pharmacology. 18

A series of eight human ovarian cancer lines grown in nude mice were used to compare the activity of hexamethylmelamine (HMM) and N2,N4,N6-trihydroxy methyl-N2,N4,N6-trimethylmelamine (trimelamol). The tumor lines differed in histological subtype and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b4bc194c6efc898d98aa20e512e1c9
https://doi.org/10.1007/bf00262280