Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Caroline A Lamb"'
Autor:
Rita Araújo, Victoria Fabris, Caroline A. Lamb, Claudia Lanari, Luisa A. Helguero, Ana M. Gil
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer (BC) is the most common type of cancer in women and, in most cases, it is hormone-dependent (HD), thus relying on ovarian hormone activation of intracellular receptors to stimulate tumor growth. Endocrine therapy (ET) aimed at preventin
Externí odkaz:
https://doaj.org/article/9c720cd5a9aa4d7fbe74c705d13a4d0c
Autor:
Andrés Elía, Leo Saldain, Silvia I. Vanzulli, Luisa A. Helguero, Caroline A. Lamb, Victoria Fabris, Gabriela Pataccini, Paula Martínez-Vazquez, Javier Burruchaga, Ines Caillet-Bois, Eunice Spengler, Gabriela Acosta Haab, Marcos Liguori, Alejandra Castets, Silvia Lovisi, María F. Abascal, Virginia Novaro, Jana Sánchez, Javier Muñoz, José M. Belizán, Martín C. Abba, Hugo Gass, Paola Rojas, Claudia Lanari
Publikováno v:
Clinical Cancer Research. 29:866-877
Purpose:Preclinical data suggest that antiprogestins inhibit the growth of luminal breast carcinomas that express higher levels of progesterone receptor isoform A (PRA) than isoform B (PRB). Thus, we designed a presurgical window of opportunity trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b912e6687a9a29640f99d418237391
https://doi.org/10.1158/1078-0432.ccr-22-2060
https://doi.org/10.1158/1078-0432.ccr-22-2060
Autor:
Claudia Lanari, Paola Rojas, Hugo Gass, Martín C. Abba, José M. Belizán, Javier Muñoz, Jana Sánchez, Virginia Novaro, María F. Abascal, Silvia Lovisi, Alejandra Castets, Marcos Liguori, Gabriela Acosta Haab, Eunice Spengler, Ines Caillet-Bois, Javier Burruchaga, Paula Martínez-Vazquez, Gabriela Pataccini, Victoria Fabris, Caroline A. Lamb, Luisa A. Helguero, Silvia I. Vanzulli, Leo Saldain, Andrés Elía
RNA-Seq and Proteomics analysis. A and B, Dot plot of relevant enriched pathways from GSEA results (Reactome and Hallmark databases) separating responsive (A) and unresponsive tumors (B). C, Immune cell deconvolution (xcell) in the different tumors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d6792c68f8f402636d49008d19cd98
https://doi.org/10.1158/1078-0432.22490276
https://doi.org/10.1158/1078-0432.22490276
Autor:
Claudia Lanari, Paola Rojas, Hugo Gass, Martín C. Abba, José M. Belizán, Javier Muñoz, Jana Sánchez, Virginia Novaro, María F. Abascal, Silvia Lovisi, Alejandra Castets, Marcos Liguori, Gabriela Acosta Haab, Eunice Spengler, Ines Caillet-Bois, Javier Burruchaga, Paula Martínez-Vazquez, Gabriela Pataccini, Victoria Fabris, Caroline A. Lamb, Luisa A. Helguero, Silvia I. Vanzulli, Leo Saldain, Andrés Elía
RNA-Seq Variant calling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a80723a943845d57a6412590544235
https://doi.org/10.1158/1078-0432.22490249
https://doi.org/10.1158/1078-0432.22490249
Autor:
Claudia Lanari, Paola Rojas, Hugo Gass, Martín C. Abba, José M. Belizán, Javier Muñoz, Jana Sánchez, Virginia Novaro, María F. Abascal, Silvia Lovisi, Alejandra Castets, Marcos Liguori, Gabriela Acosta Haab, Eunice Spengler, Ines Caillet-Bois, Javier Burruchaga, Paula Martínez-Vazquez, Gabriela Pataccini, Victoria Fabris, Caroline A. Lamb, Luisa A. Helguero, Silvia I. Vanzulli, Leo Saldain, Andrés Elía
Purpose:Preclinical data suggest that antiprogestins inhibit the growth of luminal breast carcinomas that express higher levels of progesterone receptor isoform A (PRA) than isoform B (PRB). Thus, we designed a presurgical window of opportunity trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efca7051031f2a880f05b2613d47d1f
https://doi.org/10.1158/1078-0432.c.6533123.v1
https://doi.org/10.1158/1078-0432.c.6533123.v1
Autor:
Claudia Lanari, Paola Rojas, Hugo Gass, Martín C. Abba, José M. Belizán, Javier Muñoz, Jana Sánchez, Virginia Novaro, María F. Abascal, Silvia Lovisi, Alejandra Castets, Marcos Liguori, Gabriela Acosta Haab, Eunice Spengler, Ines Caillet-Bois, Javier Burruchaga, Paula Martínez-Vazquez, Gabriela Pataccini, Victoria Fabris, Caroline A. Lamb, Luisa A. Helguero, Silvia I. Vanzulli, Leo Saldain, Andrés Elía
Morphological evaluation of CNBs and matched surgical samples; RNA-Seq analysis; Proteomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a15542d13a638249a3223b51a95718
https://doi.org/10.1158/1078-0432.22490267.v1
https://doi.org/10.1158/1078-0432.22490267.v1
Autor:
Claudia Lanari, Mariana Salatino, Gabriel A. Rabinovich, Caroline A. Lamb, Virginia Novaro, Carol A. Sartorius, Derek C. Radisky, María L. Polo, Silvia I. Vanzulli, Gabriela Pataccini, Ramiro M. Perrotta, Tomás Dalotto-Moreno, Ana Sahores, Gonzalo R. Sequeira
TS1: List of upregulated Gene Ontology biological processes, TS2: List of downregulated Gene Ontology biological processes, TS3: List of normalized differential expressed genes with MFP, TS4: Gene Ontology Biological processes from differential expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee633e4a0a3b3935829194bf1446c8a
https://doi.org/10.1158/0008-5472.22427095.v1
https://doi.org/10.1158/0008-5472.22427095.v1
Autor:
Claudia Lanari, Mariana Salatino, Gabriel A. Rabinovich, Caroline A. Lamb, Virginia Novaro, Carol A. Sartorius, Derek C. Radisky, María L. Polo, Silvia I. Vanzulli, Gabriela Pataccini, Ramiro M. Perrotta, Tomás Dalotto-Moreno, Ana Sahores, Gonzalo R. Sequeira
The role of active antitumor immunity in hormone receptor–positive (HR+) breast cancer has been historically underlooked. The aim of this study was to determine the contribution of the immune system to antiprogestin-induced tumor growth inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015daa92d363e5288c341cb3feffccf1
https://doi.org/10.1158/0008-5472.c.6512551.v1
https://doi.org/10.1158/0008-5472.c.6512551.v1
Autor:
Claudia Lanari, Mariana Salatino, Gabriel A. Rabinovich, Caroline A. Lamb, Virginia Novaro, Carol A. Sartorius, Derek C. Radisky, María L. Polo, Silvia I. Vanzulli, Gabriela Pataccini, Ramiro M. Perrotta, Tomás Dalotto-Moreno, Ana Sahores, Gonzalo R. Sequeira
Supplementary Figure 1: The NSG-R mouse model mimics an immunocompetent host.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a31e9c1ba59d584271cf311ccec730
https://doi.org/10.1158/0008-5472.22427119
https://doi.org/10.1158/0008-5472.22427119
Autor:
Claudia Lanari, J. Silvio Gutkind, Caroline A. Lamb, Luisa A. Helguero, Alfredo A. Molinolo, Eduardo Zeitlin, Rubén Martins, Silvia I. Vanzulli, Victoria Wargon, Rocío Soldati, José P. Vaqué, Sebastián Giulianelli
PDF file - 160K, ER� increase PR activity. MDA-MB-231 cells were stably transfected with human PRB (pSG5-PRB) or with the empty vector (pSG5) and different clones were obtained. The expression of PRB was evaluated by Western blot (A), using T47D ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bca609b4ca3e174ca4608fb35be9e58
https://doi.org/10.1158/0008-5472.22395515.v1
https://doi.org/10.1158/0008-5472.22395515.v1