Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Caroline, Stanton"'
Autor:
Lara Ibrahim, Caroline Stanton, Kayla Nutsch, Thu Nguyen, Chloris Li-Ma, Yeonjin Ko, Gabriel C. Lander, R. Luke Wiseman, Michael J. Bollong
SummaryCrosstalk between metabolism and stress-responsive signaling is essential to maintaining cellular homeostasis. One way this crosstalk is achieved is through the covalent modification of proteins by endogenous, reactive metabolites that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f604c075a07977bf3d77b9cf2bc156
https://doi.org/10.1101/2023.05.08.539908
https://doi.org/10.1101/2023.05.08.539908
Autor:
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L. Bulos, Jonathan Iaconelli, Arnab K. Chatterjee, R. Luke Wiseman, Peter G. Schultz, Michael J. Bollong
Publikováno v:
Proceedings of the National Academy of Sciences. 120
KEAP1 (Kelch-like ECH-associated protein), a cytoplasmic repressor of the oxidative stress responsive transcription factor Nuclear factor erythroid 2-related factor 2 (NRF2), senses the presence of electrophilic agents by modification of its sensor c
Autor:
R. Luke Wiseman, Gabriel Kline, Kayla Nutsch, Michael J. Bollong, Jessica D. Rosarda, Kelsey R. Baron, Caroline Stanton, Jeffery W. Kelly
Publikováno v:
ACS Chemical Biology
The extracellular accumulation of glutamate is a pathologic hallmark of numerous neurodegenerative diseases including ischemic stroke and Alzheimer's disease. At high extracellular concentrations, glutamate causes neuronal damage by promoting oxidati
Autor:
Sophia Z, Shalhout, Peng-Yu, Yang, Edyta M, Grzelak, Kayla, Nutsch, Sida, Shao, Claudio, Zambaldo, Jonathan, Iaconelli, Lara, Ibrahim, Caroline, Stanton, Stormi R, Chadwick, Emily, Chen, Michael, DeRan, Sijia, Li, Mitchell, Hull, Xu, Wu, Arnab K, Chatterjee, Weijun, Shen, Fernando D, Camargo, Peter G, Schultz, Michael J, Bollong
Publikováno v:
Nature chemical biology. 17(7)
The transcriptional coactivator Yes-associated protein 1 (YAP) orchestrates a proproliferative transcriptional program that controls the fate of somatic stem cells and the regenerative responses of certain tissues. As such, agents that activate YAP m