Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Caroline, Ring"'
Autor:
Mark D. Nelms, Todor Antonijevic, Caroline Ring, Danni L. Harris, Ronnie Joe Bever, Scott G. Lynn, David Williams, Grace Chappell, Rebecca Boyles, Susan Borghoff, Stephen W. Edwards, Kristan Markey
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
IntroductionThe U. S. Environmental Protection Agency’s Endocrine Disruptor Screening Program (EDSP) Tier 1 assays are used to screen for potential endocrine system–disrupting chemicals. A model integrating data from 16 high-throughput screening
Externí odkaz:
https://doaj.org/article/0529ddd8135d47368b8e5584fda41e74
Autor:
Ronnie Joe Bever, Stephen W. Edwards, Todor Antonijevic, Mark D. Nelms, Caroline Ring, Danni Harris, Scott G. Lynn, David Williams, Grace Chappell, Rebecca Boyles, Susan Borghoff, Kristan J. Markey
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: Computational models using data from high-throughput screening assays have promise for prioritizing and screening chemicals for testing under the U.S. Environmental Protection Agency’s Endocrine Disruptor Screening Program (EDSP). The
Externí odkaz:
https://doaj.org/article/6f5a3717b10f4de28b9874309c93fd28
Autor:
Timothy J. Buckley, Peter P. Egeghy, Kristin Isaacs, Ann M. Richard, Caroline Ring, Risa R. Sayre, Jon R. Sobus, Russell S. Thomas, Elin M. Ulrich, John F. Wambaugh, Antony J. Williams
Publikováno v:
Environment International, Vol 178, Iss , Pp 108097- (2023)
Exposure science is evolving from its traditional “after the fact” and “one chemical at a time” approach to forecasting chemical exposures rapidly enough to keep pace with the constantly expanding landscape of chemicals and exposures. In this
Externí odkaz:
https://doaj.org/article/270f4785953e4574b0be9e4693bd7d8b
Autor:
Kyle Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia V. Rider, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Rebecca C. Fry, Julia E. Rager
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Research in environmental health is becoming increasingly reliant upon data science and computational methods that can more efficiently extract information from complex datasets. Data science and computational methods can be leveraged to better ident
Externí odkaz:
https://doaj.org/article/1eb5b45b3f9746218e2f2940b506c6cc
Autor:
Kristin K. Isaacs, Peter Egeghy, Kathie L. Dionisio, Katherine A. Phillips, Angelika Zidek, Caroline Ring, Jon R. Sobus, Elin M. Ulrich, Barbara A. Wetmore, Antony J. Williams, John F. Wambaugh
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology. 32:820-832
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44b2afdb2f6dd5abb1e54261bf5110cc
https://doi.org/10.1038/s41370-022-00496-9
https://doi.org/10.1038/s41370-022-00496-9
Autor:
Thomas Howard, Julia E. Rager, Lisa Smeester, Jeliyah Clark, Hudson P. Santos, Jacqueline T. Bangma, Rebecca C. Fry, Vennela Avula, Lauren A. Eaves, Thomas M. O'Shea, Caroline Ring
Publikováno v:
Toxicol Sci
Molecular signatures are being increasingly integrated into predictive biology applications. However, there are limited studies comparing the overall predictivity of transcriptomic versus epigenomic signatures in relation to perinatal outcomes. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be386d595f92a85388373ef5f5c3c392
https://doi.org/10.1093/toxsci/kfab089
https://doi.org/10.1093/toxsci/kfab089
Publikováno v:
Expert Opin Drug Metab Toxicol
INTRODUCTION: Toxicity data are unavailable for many thousands of chemicals in commerce and the environment. Therefore, risk assessors need to rapidly screen these chemicals for potential risk to public health. High-throughput screening (HTS) for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b523d621d69ada2336ef01c65d75175
https://doi.org/10.1080/17425255.2021.1935867
https://doi.org/10.1080/17425255.2021.1935867
Autor:
Janice K. Britt, Caroline Ring, Daniele Wikoff, Robert A. Budinsky, Jonathan D. Urban, Laurie C. Haws, Seneca Fitch
Publikováno v:
Toxicological Sciences. 179:162-182
Regulatory agencies have derived noncancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin based on reduced sperm counts relying on single studies from a large body of evidence. Techniques such as meta-regression allow for greater use of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbc176ed4cb63d88b92d73df6be243d
https://doi.org/10.1093/toxsci/kfaa171
https://doi.org/10.1093/toxsci/kfaa171
Autor:
Akshay Badrinarayanan, Robert G. Pearce, Jon Gilbert, R. Woodrow Setzer, Barbara A. Wetmore, Derek Angus, Russell S. Thomas, Teresa Sierra, Gregory S. Honda, Roger Dinallo, John F. Wambaugh, Bradley Snodgrass, Chantel I. Nicolas, Chris Strock, Adam Brockman, Caroline Ring
Publikováno v:
Toxicol Sci
High(er) throughput toxicokinetics (HTTK) encompasses in vitro measures of key determinants of chemical toxicokinetics and reverse dosimetry approaches for in vitro-in vivo extrapolation (IVIVE). With HTTK, the bioactivity identified by any in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e48b2b141c567bfb3967a5c191f2cfc
https://doi.org/10.1093/toxsci/kfz205
https://doi.org/10.1093/toxsci/kfz205
Autor:
Milos Babic, Jeffrey C. Wolf, Caroline Ring, Kyle J LeBlanc, Grace A. Chappell, Chad M. Thompson, Mark A. Harris, Julia E. Rager
Publikováno v:
Toxicologic Pathology
Carcinogenesis of the small intestine is rare in humans and rodents. Oral exposure to hexavalent chromium (Cr(VI)) and the fungicides captan and folpet induce intestinal carcinogenesis in mice. Previously ( Toxicol Pathol. 330:48-52), we showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ccd4ad5ccf96be477cd843ecf8bd8e
http://europepmc.org/articles/PMC6827348
http://europepmc.org/articles/PMC6827348