Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

Autor: Caroline Manet, Zeyni Mansuroglu, Laurine Conquet, Violaine Bortolin, Thomas Comptdaer, Helena Segrt, Marie Bourdon, Reyene Menidjel, Nicolas Stadler, Guanfang Tian, Floriane Herit, Florence Niedergang, Sylvie Souès, Luc Buée, Marie-Christine Galas, Xavier Montagutelli, Eliette Bonnefoy

Publikováno v: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)

Abstract Background Zika virus (ZIKV) infection at postnatal or adult age can lead to neurological disorders associated with cognitive defects. Yet, how mature neurons respond to ZIKV remains substantially unexplored. Methods The impact of ZIKV infec

Externí odkaz: https://doaj.org/article/81dd2648612b489ba907fdab7786cc88

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

Autor: Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey, Sebastian Lequime, Leen Delang, Albin Fontaine, Natapong Jupatanakul, Elliott F. Miot, Stéphanie Dabo, Caroline Manet, Xavier Montagutelli, Artem Baidaliuk, Fabiana Gámbaro, Etienne Simon-Lorière, Maxime Gilsoul, Claudia M. Romero-Vivas, Van-Mai Cao-Lormeau, Richard G. Jarman, Cheikh T. Diagne, Oumar Faye, Ousmane Faye, Amadou A. Sall, Johan Neyts, Laurent Nguyen, Suzanne J. F. Kaptein, Louis Lambrechts

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher

Externí odkaz: https://doaj.org/article/c48f91d15fcb42c39e43fb6ac7859613

Susceptibility to Zika virus in a Collaborative Cross mouse strain is induced byIrf3deficiencyin vitrobut requires other variantsin vivo, not linked to the type I interferon response

Autor: Marie Bourdon, Caroline Manet, Laurine Conquet, Corentin Ramauge-Parra, Etienne Kornobis, Eliette Bonnefoy, Xavier Montagutelli

Zika virus (ZIKV) is a Flavivirus responsible for recent epidemics in Pacific Islands and in the Americas. In humans, the consequences of ZIKV infection range from asymptomatic infection to severe neurological disease such as Guillain-Barré syndrome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::229d68c118b003b0b5dc72727d40b804
https://doi.org/10.1101/2023.03.27.534491

Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations

Autor: Rosemary Sang, Martin N. Mayanja, Van-Mai Cao-Lormeau, Julius J. Lutwama, Fabien Aubry, Oumar Faye, Veasna Duong, Louis Lambrechts, Sampson Otoo, Isabelle Dusfour, Elliott F. Miot, Joel Lutomiah, John-Paul Mutebi, Alain Kohl, Caroline Manet, Anna B. Crist, Artem Baidaliuk, Xavier Montagutelli, Alongkot Ponlawat, Sarah H. Merkling, Igor Filipović, Christophe Paupy, Claudia M. E. Romero-Vivas, Jewelna Akorli, Noah H. Rose, Cheikh Tidiane Diagne, Anubis Vega-Rúa, Richard G. Jarman, Laura B. Dickson, Ousmane Faye, Davy Jiolle, Victor O. Anyango, Carolyn S. McBride, Gordana Rašić, Daria Martynow, Stéphanie Dabo, Massamba Sylla, Amadou A. Sall

Publikováno v: Science
Science, American Association for the Advancement of Science, 2020, 370 (6519), pp.991-996. ⟨10.1126/science.abd3663⟩
Science, 2020, 370 (6519), pp.991-996. ⟨10.1126/science.abd3663⟩

Domesticating Zika virus Why hasn't Zika virus (ZIKV) disease caused as much devastation in Africa, its continent of origin, as it has in the Americas? Outside of Africa, this flavivirus is transmitted by a ubiquitous mosquito subspecies, Aedes aegyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f81cd7098feb66a6565b5e9911ebd7b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03260288

Enhanced Zika virus susceptibility of globally invasive

Autor: Fabien, Aubry, Stéphanie, Dabo, Caroline, Manet, Igor, Filipović, Noah H, Rose, Elliott F, Miot, Daria, Martynow, Artem, Baidaliuk, Sarah H, Merkling, Laura B, Dickson, Anna B, Crist, Victor O, Anyango, Claudia M, Romero-Vivas, Anubis, Vega-Rúa, Isabelle, Dusfour, Davy, Jiolle, Christophe, Paupy, Martin N, Mayanja, Julius J, Lutwama, Alain, Kohl, Veasna, Duong, Alongkot, Ponlawat, Massamba, Sylla, Jewelna, Akorli, Sampson, Otoo, Joel, Lutomiah, Rosemary, Sang, John-Paul, Mutebi, Van-Mai, Cao-Lormeau, Richard G, Jarman, Cheikh T, Diagne, Oumar, Faye, Ousmane, Faye, Amadou A, Sall, Carolyn S, McBride, Xavier, Montagutelli, Gordana, Rašić, Louis, Lambrechts

Publikováno v: Science (New York, N.Y.). 370(6519)

The drivers and patterns of zoonotic virus emergence in the human population are poorly understood. The mosquito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a6da8ae1fb41044e60c7a48e985e4ee
https://pubmed.ncbi.nlm.nih.gov/33214283