Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Caroline, König"'
Autor:
Caroline König, Alfredo Vellido
Publikováno v:
BioData Mining, Vol 17, Iss 1, Pp 1-25 (2024)
Abstract Purpose The analysis of absorption, distribution, metabolism, and excretion (ADME) molecular properties is of relevance to drug design, as they directly influence the drug’s effectiveness at its target location. This study concerns their p
Externí odkaz:
https://doaj.org/article/b2fd006461574070badfbfb3b006cb7d
Autor:
Dmitry Shvarev, Caroline König, Nicole Susan, Lars Langemeyer, Stefan Walter, Angela Perz, Florian Fröhlich, Christian Ungermann, Arne Moeller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cells depend on their endolysosomal system for nutrient uptake and downregulation of plasma membrane proteins. These processes rely on endosomal maturation, which requires multiple membrane fusion steps. Early endosome fusion is promoted by
Externí odkaz:
https://doaj.org/article/18ffc3ab95944c89abfd2dfd1e010c93
Autor:
Dmitry Shvarev, Caroline König, Nicole Susan, Lars Langemeyer, Stefan Walter, Angela Perz, Florian Fröhlich, Christian Ungermann, Arne Moeller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/2e3ac21c7e864f14903697eb73abea2b
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract G protein-coupled receptors (GPCRs) are a large superfamily of cell membrane proteins that play an important physiological role as transmitters of extracellular signals. Signal transmission through the cell membrane depends on conformational
Externí odkaz:
https://doaj.org/article/bb34bfb1bd9f41f5916c78a1f2024e35
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b8095df403844c93933ec17ce85e6a5d
Autor:
Dmitry Shvarev, Jannis Schoppe, Caroline König, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann
Publikováno v:
eLife, Vol 11 (2022)
Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and pathogenic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requires HOPS, a conserved heterohexameric tethering complex. On the mem
Externí odkaz:
https://doaj.org/article/def295925ee6473dbd2d3883d11521f1
Autor:
Caroline König, Ahmed Mohamed Helmi
Publikováno v:
Sensors, Vol 20, Iss 11, p 3307 (2020)
Condition monitoring (CM) is a useful application in industry 4.0, where the machine’s health is controlled by computational intelligence methods. Data-driven models, especially from the field of deep learning, are efficient solutions for the analy
Externí odkaz:
https://doaj.org/article/2e1a91bf7fca498ca4316a1cfca2f5e7
G-Protein Coupled Receptors (GPCRs) are a big family of eukaryotic cell transmembrane proteins, responsible for numerous biological processes. From a practical viewpoint around 34\% of the drugs approved by the US Food and Drug Administration target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3d2435ff5976cf06c9d9348dd28cb8
https://doi.org/10.3233/faia220339
https://doi.org/10.3233/faia220339
Autor:
Danilo Mangaba de Camargo, Nagela Martins Souza, Téhrrie Caroline König Ferraz Pacheco, Gustavo Casteletti Alcântara, Ednelson Mariano Dota
Publikováno v:
Revista Brasileira de Cartografia, Vol 69, Iss 3 (2017)
A acelerada urbanização pela qual os países subdesenvolvidos enfrentaram a partir da década de 1960 acarretou, à esses adensamentos populacionais, precariedade habitacional e de abastecimento de água e esgoto. Esta precariedade, por sua vez, au
Externí odkaz:
https://doaj.org/article/aba17774d8184ba3a7786c8b0f619ae5
Autor:
Caroline König, Jannis Schoppe, Dmitry Shvarev, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann
Publikováno v:
eLife 11, e80901 (2022). doi:10.7554/eLife.80901
eLife 11, e80901 (2022). doi:10.7554/eLife.80901
Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and patho-genic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requiresHOPS, a c
Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and patho-genic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requiresHOPS, a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cdbb1f3709575f8990ebf950ccab91
https://doi.org/10.7554/elife.80901
https://doi.org/10.7554/elife.80901