Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Caroline, Hastings"'
Autor:
Reena Sharma, Caroline Hastings, Orna Staretz-Chacham, Julian Raiman, Martin Paucar, Ronen Spiegel, Bryan Murray, Bryan Hurst, Benny Liu, Lise Kjems, Sharon Hrynkow
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 36, Iss , Pp 100988- (2023)
Background: Niemann-Pick disease type C (NPC) is a rare, fatal, pan-ethnic, autosomal recessive lysosomal storage disease characterized by progressive major organ failure and neurodegeneration. Preclinical studies confirmed a critical role of systemi
Externí odkaz:
https://doaj.org/article/dcd1e7dc3eca4ca693e75dfa4af44df1
Autor:
Caroline Hastings, Camilo Vieira, Benny Liu, Cyrus Bascon, Claire Gao, Raymond Y. Wang, Alicia Casey, Sharon Hrynkow
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-16 (2019)
Abstract Background Niemann-Pick Disease Type C (NPC) is an inherited, often fatal neurovisceral lysosomal storage disease characterized by cholesterol accumulation in every cell with few known treatments. Defects in cholesterol transport cause seque
Externí odkaz:
https://doaj.org/article/edff1d73b6a64294a4be6accf53c3003
Autor:
Caroline Hastings
Publikováno v:
Pediatric blood & cancer, vol 70, iss 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5f8f89a01e31632efdec76d8c6ae02
https://escholarship.org/uc/item/88f9k04h
https://escholarship.org/uc/item/88f9k04h
Autor:
James, Anderst, Shannon L, Carpenter, Thomas C, Abshire, Emily, Killough, Eneida A, Mendonca, Stephen M, Downs, Cynthia, Wetmore, Carl, Allen, David, Dickens, James, Harper, Zora R, Rogers, Juhi, Jain, Anne, Warwick, Amber, Yates, Jeffrey, Hord, Jeffrey, Lipton, Hope, Wilson, Suzanne, Kirkwood, Suzanne B, Haney, Andrea Gottsegen, Asnes, Amy R, Gavril, Rebecca Greenlee, Girardet, Nancy, Heavilin, Amanda Bird Hoffert, Gilmartin, Antoinette, Laskey, Stephen A, Messner, Bethany Anne, Mohr, Shalon Marie, Nienow, Norell, Rosado, Sheila M, Idzerda, Lori A, Legano, Anish, Raj, Andrew P, Sirotnak, Heather C, Forkey, Brooks, Keeshin, Jennifer, Matjasko, Heather, Edward, Müge, Chavdar, Jorge, Di Paola, Patrick, Leavey, Doug, Graham, Caroline, Hastings, Nobuko, Hijiya, Dana, Matthews, Betty, Pace, Maria C, Velez, Dan, Wechsler, Amy, Billett, Linda, Stork, Ryan, Hooker
Publikováno v:
Pediatrics. 150(4)
Bruising or bleeding in a child can raise the concern for child abuse. Assessing whether the findings are the result of trauma and/or whether the child has a bleeding disorder is critical. Many bleeding disorders are rare, and not every child with br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43cc44b62933e08a5b6d6d38a4421339
https://pubmed.ncbi.nlm.nih.gov/36180615
https://pubmed.ncbi.nlm.nih.gov/36180615
Publikováno v:
Molecular genetics and metabolism, vol 137, iss 4
BackgroundNiemann-Pick Disease Type C1 (NPC1) is a disorder of intracellular cholesterol and lipid trafficking that leads to the accumulation of cholesterol and lipids in the late endosomal/lysosomal compartment, resulting in systemic manifestations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086a2a5463d2d1b304154852047822d4
https://doi.org/10.2139/ssrn.4133220
https://doi.org/10.2139/ssrn.4133220
Autor:
Melissa M. Hudson, Smita Bhatia, Jacqueline Casillas, Wendy Landier, Zora R. Rogers, Carl Allen, James Harper, Jeffrey Hord, Juhi Jain, Anne Warwick, Cynthia Wetmore, Amber Yates, Jeffrey Lipton, Hope Wilson, Patrick Leavey, Amy Billett, Jorge DiPaola, Doug Graham, Caroline Hastings, Dana Matthews, Betty Pace, Linda Stork, Maria C. Velez, Dan Wechsler
Publikováno v:
Pediatrics
Progress in therapy has made survival into adulthood a reality for most children, adolescents, and young adults with a cancer diagnosis today. Notably, this growing population remains vulnerable to a variety of long-term therapy-related sequelae. Sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81c55c555bd94b606d8bf8407cd7316
https://pubmed.ncbi.nlm.nih.gov/34462344
https://pubmed.ncbi.nlm.nih.gov/34462344
Autor:
Stephen P. Hunger, Robert B Marcus, William L. Carroll, A. Kim Ritchey, Brent L. Wood, Meenakshi Devidas, Julio C. Barredo, Yichen Chen, Caroline Hastings, Naomi J. Winick
Publikováno v:
Pediatr Blood Cancer
Background: Patients with late, occurring ≥18 months post-diagnosis, isolated central nervous relapse (iCNS-R) of B-acute lymphoblastic leukemia (ALL) have excellent outcomes with chemotherapy plus cranial radiotherapy, with 5-yr overall survival (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7eaad0f55a8633126fed5322ca7f2e4
https://europepmc.org/articles/PMC9020888/
https://europepmc.org/articles/PMC9020888/
Publikováno v:
Lancet (London, England). 398(10317)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2e53af3417ad2eb057681134449394
https://pubmed.ncbi.nlm.nih.gov/34895532
https://pubmed.ncbi.nlm.nih.gov/34895532
Autor:
Girish Dhall, Joseph Stanek, Megan Blue, Parth Patel, Diana Thomas, Christopher Pierson, Benita Tamrazi, Kris M Mahadeo, Jessica Fleming, Erica Bell, Katherine Miller, Olivia Grischow, Thomas Liszkay, Scott Coven, Caroline Hastings, Karen Tsui, Claire Mazewski, Gregory Friedman, Christopher Moertel, Derek Hanson, Carl Koschmann, Guy Brock, Kenneth Wong, Arnab Chakravarti, Shahab Asgharzadeh, Marvin N Nelson, Daniel Boue, Jaclyn Biegel, Elaine Mardis, Jonathan Finlay
Publikováno v:
Neuro-Oncology. 24:i192-i192
Advances in RNA and DNA profiling have identified four core molecular subgroups of medulloblastoma of prognostic significance: Sonic Hedgehog (SHH) subtype, WNT subtype, Group 3, and Group 4. Infants and young children with SHH medulloblastoma have d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::498701386341567654bb8216cd3c909c
https://doi.org/10.1093/neuonc/noac079.717
https://doi.org/10.1093/neuonc/noac079.717
Autor:
Neelam Phalke, Jong Hee Chung, Ellen B. Fung, David W. Killilea, James H. Feusner, Caroline Hastings
Publikováno v:
Pediatric bloodcancerREFERENCES. 68(9)
BACKGROUND Nutritional deficiencies in children with cancer at time of diagnosis and during treatment may negatively affect disease outcome and increase treatment-related toxicity. Yet zinc, an essential nutrient important for supporting immune funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3dec6ae9bbcc1fc676bcf2a85f6d67
https://pubmed.ncbi.nlm.nih.gov/34061438
https://pubmed.ncbi.nlm.nih.gov/34061438