Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Caroline, Fong"'
Autor:
Hazel Lote, Florentia Mousoullou, George Vlachogiannis, Andrea Lampis, Laura Satchwell, Clare Peckitt, Caroline Fong, Ruwaida Begum, Shannon Kidd, Susan Cromarty, Anderley Gordon, Charlotte Fribbens, Sheela Rao, Naureen Starling, Ian Chau, David Cunningham, Nicola Valeri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThis study aimed to identify microRNAs (miRs) as circulating biomarkers of resistance to first-line trastuzumab-based therapy in advanced HER2-positive oesophago-gastric cancer patients.MethodsA high-throughput 1015 Exiqon miRCURY LNA™ mi
Externí odkaz:
https://doaj.org/article/ce00e101c55741ff998c109728418068
Autor:
David K. Lau, Caroline Fong, Faten Arouri, Lillian Cortez, Hannah Katifi, Reyes Gonzalez-Exposito, Muhammad Bilal Razzaq, Su Li, Aislinn Macklin-Doherty, Monica Arenas Hernandez, Michael Hubank, Charlotte Fribbens, David Watkins, Sheela Rao, Ian Chau, David Cunningham, Naureen Starling
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the metabolism of fluoropyrimidines. Variations in the encoding DPYD gene are associated with severe fluoropyrimidine toxicity and up-front dose reductions are recommended.
Externí odkaz:
https://doaj.org/article/8c4c528d564e402aa51ff80d19849ea5
Autor:
Mark Uhlik, Dr Caroline Fong
Publikováno v:
Immuno Oncology Insights. :513-525
Publikováno v:
Monday, April 24.
Autor:
Jasmeet Sidhu, Ashish Narayan Masurekar, Manash Pratim Gogoi, Caroline Fong, Tasos Ioannou, Taha Lodhi, Catriona Parker, Jizhong Liu, Amy A. Kirkwood, Anthony V. Moorman, Kiranmoy Das, Nicholas J. Goulden, Ajay Vora, Vaskar Saha, Shekhar Krishnan
Publikováno v:
British Journal of Haematology. 198:142-150
Publikováno v:
Current treatment options in oncologyReferences and Recommended ReadingPapers of particular interest, published recently, have been highlighted as: • Of importance. 23(9)
Gastric cancer is an aggressive malignancy, requiring a multimodality approach to achieve optimal curative rates even when the disease is amenable to surgical resection. Neoadjuvant and adjuvant approaches differ across the globe-a preference for per
Autor:
Caroline Fong, Ian Chau
Publikováno v:
Cancers. 14(15)
Gastric cancer is a leading cause of cancer-related deaths globally. Human epidermal growth receptor 2 (HER2) overexpression of HER2 gene amplification is present in 20% of gastric cancers and defines a subset amenable to HER2-directed therapeutics.
Autor:
Hazel Lote, Florentia Mousoullou, George Vlachogiannis, Caroline Fong, Laura Satchwell, Clare Peckitt, Ruwaida Begum, Shannon Kidd, Susan Cromarty, Anderley Gordon, Charlotte Victoria Fribbens, David J. Watkins, Sheela Rao, Ian Chau, Naureen Starling, David Cunningham, Nicola Valeri
Publikováno v:
Journal of Clinical Oncology. 41:419-419
419 Background: A predictive biomarker for resistance to trastuzumab in HER2 positive oesophago-gastric cancer would refine patient selection. Our preclinical studies suggest that patients with HIGH baseline plasma miR-148a-3p levels will experience
Autor:
Jasmeet, Sidhu, Ashish Narayan, Masurekar, Manash Pratim, Gogoi, Caroline, Fong, Tasos, Ioannou, Taha, Lodhi, Catriona, Parker, Jizhong, Liu, Amy A, Kirkwood, Anthony V, Moorman, Kiranmoy, Das, Nicholas J, Goulden, Ajay, Vora, Vaskar, Saha, Shekhar, Krishnan
Publikováno v:
British journal of haematology. 198(1)
In successive UK clinical trials (UKALL 2003, UKALL 2011) for paediatric acute lymphoblastic leukaemia (ALL), polyethylene glycol-conjugated E. coli L-asparaginase (PEG-EcASNase) 1000 iu/m
Autor:
Benjamin R. Challoner, Andrew Woolston, David Lau, Marta Buzzetti, Caroline Fong, Louise J. Barber, Gayathri Anandappa, Richard Crux, Ioannis Assiotis, Kerry Fenwick, Ruwaida Begum, Dipa Begum, Tom Lund, Nanna Sivamanoharan, Harold B. Sansano, Melissa Domingo-Arada, Amina Tran, Bryony Eccles, Richard Ellis, Stephen Falk, Mark Hill, Daniel Krell, Nirupa Murugaesu, Luke Nolan, Vanessa Potter, Mark Saunders, Kai-Keen Shiu, Sebastian Guettler, James L. Alexander, Héctor Lázare-Iglesias, James Kinross, Jamie Murphy, Katharina von Loga, David Cunningham, Ian Chau, Naureen Starling, Juan Ruiz-Bañobre, Tony Dhillon, Marco Gerlinger
Mismatch repair deficient colorectal cancers have high mutation loads and many respond to immune checkpoint-inhibitors. We investigated how genetic and immune landscapes co-evolve in these tumors. All cases had high truncal mutation loads. Driver abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0034cbd8dbfa0674f6a03528d18c73
https://doi.org/10.1101/2022.02.16.479224
https://doi.org/10.1101/2022.02.16.479224