Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Carolina dos Santos Passos"'
Autor:
Scott R. Burlingham, Nicole F. Wong, Lindsay Peterkin, Lily Lubow, Carolina Dos Santos Passos, Orion Benner, Michael Ghebrial, Thomas P. Cast, Matthew A. Xu-Friedman, Thomas C. Südhof, Soham Chanda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Neuronal communication relies on matching different neurostransmitter types with their appropriate receptors. The authors here demonstrate that release of a novel neurotransmitter from presynaptic terminals can induce both the accumulation and activa
Externí odkaz:
https://doaj.org/article/9d882e0d844f4effa3e0531c399f808b
Publikováno v:
Bio-Protocol, Vol 12, Iss 5 (2022)
Double-strand breaks (DSBs) are lesions in DNA that, if not properly repaired, can cause genomic instability, oncogenesis, and cell death. Multiple chromatin posttranslational modifications (PTMs) play a role in the DNA damage response to DSBs. Among
Externí odkaz:
https://doaj.org/article/001faff10f6147d0af9ba04b3b0d9946
Autor:
Geanderson Bannwart, Amélia T. Henriques, Carolina dos Santos Passos, Silvana Maria de Oliveira Santin, Cecília M. A. de Oliveira, Armando M. Pomini, Cleuza C. da Silva, Luiz Carlos Klein-Júnior, Matheus A. Peixoto, Boniek Vaz Gontijo, Lucilia Kato
Publikováno v:
Natural Product Research. 35:5465-5469
Aspidosperma macrocarpon Mart., popularly known as ‘guatambu’ or ‘peroba’, is found from North American (Mexico) to South American (Argentina) continents and in Brazil. Two indole alkaloids were isolated from leaves of A. macrocarpon, kopsano
Autor:
Carolina Dos Santos Passos, Tingting Yao, Robert E. Cohen, Yun-Seok Choi, Christopher D. Snow
Publikováno v:
The Journal of Cell Biology
Ubiquitin conjugation to histone lysines regulates diverse processes such as gene silencing, transcriptional elongation, and DNA repair. Combining an avidity-based design strategy with molecular dynamics simulations, dos Santos Passos et al. develop
Autor:
Matheus Ardenghi, Peixoto, Lucilia, Kato, Cecília Maria, Alves de Oliveira, Boniek, Gontijo, Cleuza Conceição, da Silva, Armando Mateus, Pomini, Luiz C, Klein-Júnior, Carolina Dos Santos, Passos, Amélia T, Henriques, Geanderson, Bannwart, Silvana Maria de Oliveira, Santin
Publikováno v:
Natural product research. 35(23)
Autor:
Luiz Carlos Klein-Junior, Carolina dos Santos Passos, Juliana Salton, Fernanda Gobbi de Bitencourt, Luis Funez, Jean Paulo de Andrade, Jonathan Parra Villalobos, Sérgio Augusto de Loreto Bordignon, André Luis Gasper, Yvan Vander Heyden, Amélia Teresinha Henriques
Publikováno v:
Vrije Universiteit Brussel
In the present study, the effects were evaluated of alkaloid fractions (AFs) from Psychotria species and correlated genera, Palicourea and Rudgea, on monoamine oxidases (MAOs) and cholinesterases (ChEs). By HPLC-DAD and UPLC-DAD-MS analyses, indole a
Autor:
Amélia T. Henriques, Juliana Salton, Fernanda Gobbi de Bitencourt, Carolina dos Santos Passos, Sérgio Augusto de Loreto Bordignon, Letícia J. Danielli, Maria Angélica Recalde-Gil, Luiz Carlos Klein-Júnior
Publikováno v:
Journal of Essential Oil Bearing Plants. 19:1762-1768
The essential oils (EOs) obtained from Peperomia tetraphylla (PT), P. pereskiifolia (PP), and P. glabella (PG), were evaluated in MAO-A and -B in vitro inhibitory assays. The oils demonstrated IC50...
Autor:
Vincent Zwick, Giuseppe Marco Randazzo, Claudia A. Simões-Pires, Muriel Cuendet, Philippe Bertrand, Carolina dos Santos Passos, Nadine Martinet, Charlotte Petit, Alessandra Nurisso
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 20 (2016) pp. 4955-4959
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 20 (2016) pp. 4955-4959
In recent years, the role of HDAC6 in neurodegeneration has been partially elucidated, which led some authors to propose HDAC6 inhibitors as a therapeutic strategy to treat neurodegenerative diseases. In an effort to develop a selective HDAC6 inhibit
Autor:
Carolina dos Santos Passos, Pierre-Alain Carrupt, Daumantas Matulis, Alessandra Nurisso, Jelena Jachno, Lucie Ryckewaert, Claudia A. Simões-Pires, Lionel Sacconnay, Giuseppe Marco Randazzo, Vilma Michailovienė, Asta Zubrienė, Charlotte Petit
Publikováno v:
European Journal of Pharmaceutical Sciences. 85:59-67
Sirtuins (SIRTs) are a family of enzymes able to catalyze the deacetylation of the N-acetyl lysines of both histone and non-histone substrates. Inhibition of SIRTs catalytic activity was recently reported in the literature as being beneficial in huma
Autor:
Fernanda Gobbi de Bitencourt, Juliana Salton, Sérgio Augusto de Loreto Bordignon, Amélia T. Henriques, Tiago Juliano Tasso de Souza, Luiz Carlos Klein-Júnior, Carolina dos Santos Passos
Publikováno v:
Pharmaceutical Biology. 54:1071-1076
Monoamine oxidase (MAO) inhibitors are used in the treatment of depression, anxiety disorders, and the symptomatic treatment of Parkinson's disease. Eryngium, the most representative of the Apiaceae family, is well known for the presence of essential