Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carolina Tängemo"'
Autor:
Emma Kay, Rouven Stulz, Cécile Becquart, Jelena Lovric, Carolina Tängemo, Aurélien Thomen, Dženita Baždarević, Neda Najafinobar, Anders Dahlén, Anna Pielach, Julia Fernandez-Rodriguez, Roger Strömberg, Carina Ämmälä, Shalini Andersson, Michael Kurczy
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 463 (2022)
The delivery of antisense oligonucleotides (ASOs) to specific cell types via targeted endocytosis is challenging due to the low cell surface expression of target receptors and inefficient escape of ASOs from the endosomal pathway. Conjugating ASOs to
Externí odkaz:
https://doaj.org/article/0a250bb207f54135b69457a41395d273
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 813-825 (2011)
A central feature of Niemann-Pick Type C (NPC) disease is sequestration of cholesterol and glycosphingolipids in lysosomes. A large phenotypic variability, on both a clinical as well as a molecular level, challenges NPC diagnosis. For example, substa
Externí odkaz:
https://doaj.org/article/885a862f188d4dd79d0be40f5fbce00d
Autor:
Emma Kay, Rouven Stulz, Cécile Becquart, Jelena Lovric, Carolina Tängemo, Aurélien Thomen, Dženita Baždarević, Neda Najafinobar, Anders Dahlén, Anna Pielach, Julia Fernandez-Rodriguez, Roger Strömberg, Carina Ämmälä, Shalini Andersson, Michael Kurczy
Publikováno v:
Pharmaceutics; Volume 14; Issue 2; Pages: 463
The delivery of antisense oligonucleotides (ASOs) to specific cell types via targeted endocytosis is challenging due to the low cell surface expression of target receptors and inefficient escape of ASOs from the endosomal pathway. Conjugating ASOs to
Autor:
Nadia Gul, Carolina Tängemo, Chandu Ala, Martin O. Bergo, Rosie Perkins, Sanna Linsefors, Per Lindahl, Samuel Tuyizere, Erik Larsson, Joakim Karlsson, Zhiyuan Zou
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The mut-T homolog-1 (MTH1) inhibitor TH588 has shown promise in preclinical cancer studies but its targeting specificity has been questioned. Alternative mechanisms for the anti-cancer effects of TH588 have been suggested but the question remains unr
Publikováno v:
Journal of Leukocyte Biology. 83:139-148
Neutrophil apoptosis is important for the termination of inflammatory reactions, in that it ensures placid clearance of these potently cytotoxic cells. Various proinflammatory cytokines delay neutrophil apoptosis, which may result in accumulation of
Publikováno v:
Journal of cell science. 128(7)
The Golgi is a highly organized and dynamic organelle that receives and distributes material from and to the endoplasmic reticulum (ER) and the endocytic pathway. One open question about Golgi organization is whether it is solely based on ER-to-Golgi
Autor:
Eva Skiöldebrand, Anders Lindahl, Carolina Tängemo, Katarina Junevik, Helena Barreto Henriksson, Helena Brisby, Johan Mattsson
Publikováno v:
Stem Cell Research & Therapy
Introduction Potential stem cell niches (SNs) were recently reported in intervertebral discs (IVDs) and knee joints (KJs) in different mammals (located adjacent to the epiphyseal plate; EP). The aim here was to examine further possible cellular migra
Autor:
Emmanuel G. Reynaud, Ernst H. K. Stelzer, Uta Haselmann, Jeremy C. Simpson, Carolina Tängemo, Rainer Pepperkok, Claude Antony, Paolo Ronchi, Julien Colombelli
Publikováno v:
Journal of cell science. 124(Pt 6)
The Golgi complex has a central role in the secretory pathway of all higher organisms. To explain the synthesis of its unique stacked structure in mammalian cells, two major models have been proposed. One suggests that it is synthesized de novo from
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 813-825 (2011)
A central feature of Niemann-Pick Type C (NPC) disease is sequestration of cholesterol and glycosphingolipids in lysosomes. A large phenotypic variability, on both a clinical as well as a molecular level, challenges NPC diagnosis. For example, substa
Autor:
Julien, Colombelli, Carolina, Tängemo, Uta, Haselman, Claude, Antony, Ernst H K, Stelzer, Rainer, Pepperkok, Emmanuel G, Reynaud
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 457
Correlative microscopy is a hybrid method that allows the localization of events observed under visible, ultraviolet, or infrared light, at molecular and submolecular levels, combining two microscopy techniques. However, the main limitation of correl