Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Carolina REDUZZI"'
Autor:
Serena Di Cosimo, Marco Silvestri, Cinzia De Marco, Alessia Calzoni, Maria Carmen De Santis, Maria Grazia Carnevale, Carolina Reduzzi, Massimo Cristofanilli, Vera Cappelletti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Chromosomal Instability (CIN) is a common and evolving feature in breast cancer. Large-scale Transitions (LSTs), defined as chromosomal breakages leading to gains or losses of at least 10 Mb, have recently emerged as a metric of CIN due to t
Externí odkaz:
https://doaj.org/article/5e21cc35fec64b789fb53b1caf488296
Autor:
Lorenzo Gerratana, Andrew A. Davis, Marko Velimirovic, Katherine Clifton, Whitney L. Hensing, Ami N. Shah, Charles S. Dai, Carolina Reduzzi, Paolo D’Amico, Firas Wehbe, Arielle Medford, Seth A. Wander, William J. Gradishar, Amir Behdad, Fabio Puglisi, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background although being central for the biology and druggability of hormone-receptor positive, HER2 negative metastatic breast cancer (MBC), ESR1 and PIK3CA mutations are simplistically dichotomized as mutated or wild type in current clini
Externí odkaz:
https://doaj.org/article/e709c732d873422f9a1a421cdc570023
Autor:
Andrew A. Davis, Lorenzo Gerratana, Katherine Clifton, Arielle J. Medford, Marko Velimirovic, Whitney L. Hensing, Leslie Bucheit, Ami N. Shah, Paolo D'Amico, Carolina Reduzzi, Qiang Zhang, Charles S. Dai, Elyssa N. Denault, Nusayba A. Bagegni, Mateusz Opyrchal, Foluso O. Ademuyiwa, Ron Bose, William J. Gradishar, Amir Behdad, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104316- (2022)
Summary: Background: Limited data exist to characterise molecular differences in circulating tumour DNA (ctDNA) for patients with invasive lobular carcinoma (ILC). We analysed metastatic breast cancer patients with ctDNA testing to assess genomic dif
Externí odkaz:
https://doaj.org/article/07b125b3c92b42acba72a92a3f8e5d48
Autor:
Rokana Taftaf, Xia Liu, Salendra Singh, Yuzhi Jia, Nurmaa K. Dashzeveg, Andrew D. Hoffmann, Lamiaa El-Shennawy, Erika K. Ramos, Valery Adorno-Cruz, Emma J. Schuster, David Scholten, Dhwani Patel, Youbin Zhang, Andrew A. Davis, Carolina Reduzzi, Yue Cao, Paolo D’Amico, Yang Shen, Massimo Cristofanilli, William A. Muller, Vinay Varadan, Huiping Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Circulating tumor cell (CTC) clusters are more efficient at mediating metastasis as compared to single cells and are associated with poor prognosis in breast cancer. Here, the authors show that ICAM1 is enriched in CTC clusters and its loss suppresse
Externí odkaz:
https://doaj.org/article/017f7ea6455b4bbfa2e1554f4c8f4748
Autor:
Chia-Feng Tsai, Pengfei Zhang, David Scholten, Kendall Martin, Yi-Ting Wang, Rui Zhao, William B. Chrisler, Dhwani B. Patel, Maowei Dou, Yuzhi Jia, Carolina Reduzzi, Xia Liu, Ronald J. Moore, Kristin E. Burnum-Johnson, Miao-Hsia Lin, Chuan-Chih Hsu, Jon M. Jacobs, Jacob Kagan, Sudhir Srivastava, Karin D. Rodland, H. Steven Wiley, Wei-Jun Qian, Richard D. Smith, Ying Zhu, Massimo Cristofanilli, Tao Liu, Huiping Liu, Tujin Shi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Tsai, Zhang, Scholten et al. develop a surfactant- assisted one-pot sample preparation coupled with mass spectrometry method (SOP-MS) for label-free global single-cell proteomics. This method allows researchers to measure hundreds of proteins from si
Externí odkaz:
https://doaj.org/article/a689739f342a49b381b96ffab619ff1e
Autor:
Maroua Manai, Ines ELBini-Dhouib, Pascal Finetti, Haifa Bichiou, Carolina Reduzzi, Dorra Aissaoui, Naziha Ben-Hamida, Emilie Agavnian, Najet Srairi-Abid, Marc Lopez, Fatma Amri, Lamia Guizani-Tabbane, Khaled Rahal, Karima Mrad, Mohamed Manai, Daniel Birnbaum, Emilie Mamessier, Massimo Cristofanilli, Hamouda Boussen, Maher Kharrat, Raoudha Doghri, François Bertucci
Publikováno v:
Cells, Vol 11, Iss 18, p 2926 (2022)
Inflammatory breast cancer (IBC) is the most pro-metastatic form of breast cancer (BC). We previously demonstrated that protein overexpression of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) protein was associated with shorter survival in I
Externí odkaz:
https://doaj.org/article/f0bd0446e84446379a1c35782ae0f216
Autor:
Vera Cappelletti, Elena Verzoni, Raffaele Ratta, Marta Vismara, Marco Silvestri, Rosanna Montone, Patrizia Miodini, Carolina Reduzzi, Melanie Claps, Pierangela Sepe, Maria Grazia Daidone, Giuseppe Procopio
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1475 (2020)
Circulating tumor cells (CTCs) are promising biomarkers for prognosis, therapeutic response prediction, and treatment monitoring in cancer patients. Despite its epithelial origin, renal cell carcinoma (RCC) shows low expression of epithelial markers
Externí odkaz:
https://doaj.org/article/5b283c02f4c141f6873ad3970052d5a9
Autor:
Carolina REDUZZI, Lorenzo Gerratana, Youbin Zhang, Maroua MANAI, Paolo D’Amico, Andrew A. Davis, Jeannine Donahue, Ami N. Shah, Massimo Cristofanilli
Publikováno v:
Cancer Research. 83:P2-26
Background: Circulating tumor cells (CTCs) in breast cancer (BC) are commonly defined as epithelial cells (EPCAM and cytokeratin (CK) positive), lacking the universal blood cell marker CD45. Nonetheless, CTCs expressing both CK and CD45 (= dual-posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f29fa56caa381876ce197657b84dc3
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-06
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-06
Autor:
Maroua Manai, Ines Bini, Pascal Finetti, Haifa Bichiou, Carolina Reduzzi, Naziha Ben Hamida, Marc Lopez, Khaled Rahal, Karima Mrad, Mohamed Manai, Massimo Cristofanilli, Hamouda Boussen, Raoudha Doghri, Maher Kharrat, François Bertucci
Publikováno v:
Cancer Research. 83:P6-10
Background. Because of its high metastatic potential, inflammatory breast cancer (IBC) is the most lethal and aggressive form of breast cancer. We previously demonstrated that Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) protein overexpress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f1a54ef3b97db6992afafa4cea853c
https://doi.org/10.1158/1538-7445.sabcs22-p6-10-15
https://doi.org/10.1158/1538-7445.sabcs22-p6-10-15
Autor:
Lorenzo Gerratana, Andrew A. Davis, Marko Velimirovic, Carolina Reduzzi, Katherine Clifton, Leslie Bucheit, Whitney L. Hensing, Ami N. Shah, Tania Pivetta, Charles S. Dai, Paolo D'Amico, Firas Wehbe, Arielle Medford, Seth A. Wander, William J. Gradishar, Amir Behdad, Cynthia X. Ma, Fabio Puglisi, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
JCO Precision Oncology.
PURPOSE As the continuation beyond progression (BP) of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) is becoming increasingly attractive for the treatment of patients with hormone receptor (HR)–positive, human epidermal growth factor receptor 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::293e3bc386f821cc9a670a7efcfddf27
https://doi.org/10.1200/po.22.00531
https://doi.org/10.1200/po.22.00531