Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Carolina Q, Sacramento"'
Autor:
Aline D. Purificação, Sabrina Silva-Mendonça, Luiza V. Cruz, Carolina Q. Sacramento, Jairo R. Temerozo, Natalia Fintelman-Rodrigues, Caroline Souza de Freitas, Bruna Fleck Godoi, Miguel Menezes Vaidergorn, Juliana Almeida Leite, Luis Carlos Salazar Alvarez, Murillo V. Freitas, Meryck F. B. Silvac, Bianca A. Martin, Renata F. V. Lopez, Bruno J. Neves, Fabio T. M. Costa, Thiago M. L. Souza, Flavio da Silva Emery, Carolina Horta Andrade, M. Cristina Nonato
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11418-11430 (2024)
Externí odkaz:
https://doaj.org/article/39a3e0cbd8ee4c37b266127366a305cb
Autor:
Thiago Moreno L. Souza, Vagner D. Pinho, Cristina F. Setim, Carolina Q. Sacramento, Rodrigo Marcon, Natalia Fintelman-Rodrigues, Otavio A. Chaves, Melina Heller, Jairo R. Temerozo, André C. Ferreira, Mayara Mattos, Patrícia B. Momo, Suelen S. G. Dias, João S. M. Gesto, Filipe Pereira-Dutra, João P. B. Viola, Celso Martins Queiroz-Junior, Lays Cordeiro Guimarães, Ian Meira Chaves, Pedro Pires Goulart Guimarães, Vivian Vasconcelos Costa, Mauro Martins Teixeira, Dumith Chequer Bou-Habib, Patrícia T. Bozza, Anderson R. Aguillón, Jarbas Siqueira-Junior, Sergio Macedo-Junior, Edineia L. Andrade, Guilherme P. Fadanni, Sara E. L. Tolouei, Francine B. Potrich, Adara A. Santos, Naiani F. Marques, João B. Calixto, Jaime A. Rabi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The search for antivirals against SARS-CoV-2 continue due to the emergence of variants of concerns, able to escape the vaccinal humoral response. In this work, authors pre-clinically explore the potential of kinetin against SARS-CoV-2, which could be
Externí odkaz:
https://doaj.org/article/7d55dbfc83a94333a82eee70353ce909
Autor:
Jairo R. Temerozo, Natalia Fintelman-Rodrigues, Monique Cristina dos Santos, Eugenio D. Hottz, Carolina Q. Sacramento, Aline de Paula Dias da Silva, Samuel Coelho Mandacaru, Emilly Caroline dos Santos Moraes, Monique R. O. Trugilho, João S. M. Gesto, Marcelo Alves Ferreira, Felipe Betoni Saraiva, Lohanna Palhinha, Remy Martins-Gonçalves, Isaclaudia Gomes Azevedo-Quintanilha, Juliana L. Abrantes, Cássia Righy, Pedro Kurtz, Hui Jiang, Hongdong Tan, Carlos Morel, Dumith Chequer Bou-Habib, Fernando A. Bozza, Patrícia T. Bozza, Thiago Moreno L. Souza
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background Critically ill 2019 coronavirus disease (COVID-19) patients under invasive mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general population. Although progression from mild to severe COVID-19 has been
Externí odkaz:
https://doaj.org/article/6e852a90651e4bdaae661b0aaad38148
Autor:
Xuanting Wang, Carolina Q. Sacramento, Steffen Jockusch, Otávio Augusto Chaves, Chuanjuan Tao, Natalia Fintelman-Rodrigues, Minchen Chien, Jairo R. Temerozo, Xiaoxu Li, Shiv Kumar, Wei Xie, Dinshaw J. Patel, Cindy Meyer, Aitor Garzia, Thomas Tuschl, Patrícia T. Bozza, James J. Russo, Thiago Moreno L. Souza, Jingyue Ju
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
In this paper, the hepatitis C virus inhibitors Pibrentasvir and Ombitasvir are found to inhibit the SARS-CoV-2 exonuclease and are shown to have therapeutic potential when combined with SARS-CoV-2 polymerase inhibitors in viral cell cultures.
Externí odkaz:
https://doaj.org/article/421885d8a61b464da42eeec94cc924d8
Autor:
André C. Ferreira, Carolina Q. Sacramento, Filipe S. Pereira-Dutra, Natália Fintelman-Rodrigues, Priscila P. Silva, Mayara Mattos, Caroline S. de Freitas, Andressa Marttorelli, Gabrielle R. de Melo, Mariana M. Campos, Isaclaudia G. Azevedo-Quintanilha, Aluana S. Carlos, João Vítor Emídio, Cristiana C. Garcia, Patrícia T. Bozza, Fernando A. Bozza, Thiago M. L. Souza
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionInfluenza A virus (IAV) is one of the leading causes of respiratory tract infections in humans, representing a major public health concern. The various types of cell death have a crucial role in IAV pathogenesis because this virus may tri
Externí odkaz:
https://doaj.org/article/0836dd826fee4902a18acb63980080a8
Autor:
Mariana Brandi Mendonça Pinheiro, Stephane Vicente Rozini, Anna Cecíllia Quirino-Teixeira, Giselle Barbosa-Lima, Juliana F. Lopes, Carolina Q. Sacramento, Fernando A. Bozza, Patrícia T. Bozza, Eugenio D. Hottz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionDengue is an arthropod-born disease caused by dengue virus (DENV), that may manifest as a mild illness or severe form, characterized by hemorrhagic fever and shock. Nitric oxide (NO) is a vasodilator signaling molecule and an inhibitor of
Externí odkaz:
https://doaj.org/article/ef1eec77d1c54e9fa5dc0b041e0a59ea
Autor:
Natalia Fintelman-Rodrigues, Aline P.D. da Silva, Monique Cristina dos Santos, Felipe B. Saraiva, Marcelo A. Ferreira, João Gesto, Danielle A.S. Rodrigues, André M. Vale, Isaclaudia G. de Azevedo, Vinícius C. Soares, Hui Jiang, Hongdong Tan, Diogo A. Tschoeke, Carolina Q. Sacramento, Fernando A. Bozza, Carlos M. Morel, Patrícia T. Bozza, Thiago Moreno L. Souza
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 5, Pp 1446-1453 (2021)
The dynamics underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection remain poorly understood. We identified a small cluster of patients in Brazil who experienced 2 episodes of coronavirus disease (COVID-19) in March and l
Externí odkaz:
https://doaj.org/article/012ca42c98e74c1197d39a712f22fc7d
Autor:
André C. Ferreira, Vinicius Cardoso Soares, Isaclaudia G. de Azevedo-Quintanilha, Suelen da Silva Gomes Dias, Natalia Fintelman-Rodrigues, Carolina Q. Sacramento, Mayara Mattos, Caroline S. de Freitas, Jairo R. Temerozo, Lívia Teixeira, Eugenio Damaceno Hottz, Ester A. Barreto, Camila R. R. Pão, Lohanna Palhinha, Milene Miranda, Dumith Chequer Bou-Habib, Fernando A. Bozza, Patrícia T. Bozza, Thiago Moreno L. Souza
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in critically ill patients. A better comprehension of SARS-CoV-2-induced monocyte death
Externí odkaz:
https://doaj.org/article/7f1d84675e3f4ca48d979b928e9f0e90
Autor:
Ana C. Puhl, Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Tatyana Almeida Tavella, Fabio Trindade Maranhão Costa, Stuart Weston, James Logue, Matthew Frieman, Lakshmanane Premkumar, Kenneth H. Pearce, Brett L. Hurst, Carolina Horta Andrade, James A. Levi, Nicole J. Johnson, Samantha C. Kisthardt, Frank Scholle, Thiago Moreno L. Souza, Nathaniel John Moorman, Ralph S. Baric, Peter B. Madrid, Sean Ekins
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7454-7468 (2021)
Externí odkaz:
https://doaj.org/article/f5c5fda4ba7d411a9be4f5d7993c395f
Autor:
Lívia Teixeira, Jairo R. Temerozo, Filipe S. Pereira-Dutra, André Costa Ferreira, Mayara Mattos, Barbara Simonson Gonçalves, Carolina Q. Sacramento, Lohanna Palhinha, Tamires Cunha-Fernandes, Suelen S. G. Dias, Vinicius Cardoso Soares, Ester A. Barreto, Daniella Cesar-Silva, Natalia Fintelman-Rodrigues, Camila R. R. Pão, Caroline S. de Freitas, Patrícia A. Reis, Eugenio D. Hottz, Fernando A. Bozza, Dumith C. Bou-Habib, Elvira M. Saraiva, Cecília J. G. de Almeida, João P. B. Viola, Thiago Moreno L. Souza, Patricia T. Bozza
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical studies, statins have been identified as beneficial to hospitalized patients with
Externí odkaz:
https://doaj.org/article/39df5290aece4fe5890ecbf76dc10dc2