Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carolina Muriel"'
Autor:
Gonzalo Lendinez-Sanchez, Tamara Diaz-Redondo, Marcos Iglesias Campos, Javier Porta Pelayo, José María Porta Pelayo, Carolina Muriel-López
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 386-391 (2024)
Introduction: Ataxia-Telangiectasia Mutated (ATM) is a cancer predisposition gene; carriers of germline pathogenic variants have an increased risk of developing malignancies, including breast, prostate, pancreatic, and ovarian cancer. Most ATM varian
Externí odkaz:
https://doaj.org/article/2e5b6b285c5e4ed59f185fa74f33cc3c
Autor:
Bella Pajares, Javier Porta, Jose María Porta, Cristina Fernández-de Sousa, Ignacio Moreno, Daniel Porta, Gema Durán, Tamara Vega, Inmaculada Ortiz, Carolina Muriel, Emilio Alba, Antonia Márquez
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background The BRCA1/2 mutation profile varies in Spain according to the geographical area studied. The mutational profile of BRCA1/2 in families at risk for hereditary breast and ovarian cancer has not so far been reported in Andalusia (sou
Externí odkaz:
https://doaj.org/article/81530c87878748e7bf11b09d7c83bce2
Autor:
Juliana Castaño-Rendón, Sebastián Sánchez López, Andrés Padierna, María Palacio, Laura Tobon, María Ossa, Carolina Muriel, Johana Tello, Fabián Jaimes
Publikováno v:
The Southwest Respiratory and Critical Care Chronicles. 10:1-9
Introduction: Approval of generic drugs requires only bioequivalence studies. Some research suggests that generic vancomycin is not clinically equivalent to the branded drug, and this exposes patients to therapeutic failure and the development of mic
Autor:
Jean-Luc Van Laethem, Frederico Longo Muñoz, Thea Kalebic, Khaldoun Almhanna, Maria Alsina, Carolina Muriel Lopez, Antonio Cubillo Gracian, Hadi Danaee, Irfan Firdaus, Zhan Ye, Adedigbo Fasanmade, Johanna C. Bendell, Wells A. Messersmith, David Wright, Richard A. Hubner, Maria Luisa Limon Miron
Publikováno v:
Investigational New Drugs. 35:235-241
Background The first-in-class antibody-drug conjugate TAK-264 (formerly MLN0264) consists of an antibody targeting guanylyl cyclase C (GCC) conjugated to monomethyl auristatin E (MMAE) via a peptide linker. This phase II study evaluated the efficacy
Autor:
Jaime Feliu, Antonio Cubillo Gracian, Jean-Luc Van Laethem, Richard A. Hubner, Thea Kalebic, Johanna C. Bendell, Jason E. Faris, Naureen Starling, Carolina Muriel Lopez, Teresa Macarulla Mercade, Huyuan Yang, Khaldoun Almhanna, Alain Bols, Hadi Danaee, Adedigbo Fasanmade, Carmen Guillén-Ponce, Wells A. Messersmith, Peter C. Enzinger, Devalingham Mahalingham, David Wright
Publikováno v:
Investigational new drugs. 35(5)
Background This phase II open-label, multicenter study evaluated the efficacy, safety, and tolerability of TAK-264 in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C (GCC). Methods Patie
Autor:
Carolina Muriel Lopez, P. Pardo, Miguel F. Sanmamed, Marta Izquierdo, Emilio Esteban, Pablo Martínez-Camblor, Guillermo Crespo, J.P. Berros, Paula Jiménez Fonseca, Aurora Astudillo
Publikováno v:
Investigational New Drugs. 30:2443-2449
Introduction The analysis of predictive factors of response may aid in predicting which patients with advanced renal cell carcinoma (RCC) would be good candidates for systemic treatments. Materials and methods The expression of several biomarkers was
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jason E. Faris, Carmen Guillén-Ponce, Alain Bols, Thea Kalebic, Jaime Feliu Batlle, Antonio Cubillo Gracian, Jean-Luc Van Laethem, Carolina Muriel Lopez, Devalingham Mahalingham, Hadi Danaee, Naureen Starling, Huyuan Yang, Wells A. Messersmith, Johanna C. Bendell, Peter C. Enzinger, Teresa Macarulla Mercade, David Wright, Adedigbo Fasanmade, Richard A. Hubner, Khaldoun Almhanna
Publikováno v:
Cancer Research. 76:CT117-CT117
TAK-264 (formerly MLN0264) is a novel ADC consisting of a human monoclonal antibody that specifically targets GCC, the potent microtubule disrupting agent monomethyl auristatin E (MMAE), and a linker. GCC is selectively expressed in the gastrointesti
Autor:
Jean-Luc Van Laethem, Khaldoun Almhanna, Adedigbo Fasanmade, Maria Alsina, Wells A. Messersmith, Thea Kalebic, Johanna C. Bendell, Carolina Muriel Lopez, Maria Luisa Limon Miron, Hadi Danaee, Huyuan Yang, Richard A. Hubner, Antonio Cubillo Gracian, David Wright, Federico Longo Muñoz
Publikováno v:
Cancer Research. 76:CT107-CT107
Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA Gastric cancer is the third-leading cause of cancer-related deaths worldwide. Outcomes of current treatment regimens remain unsatisfactory, particularly in pts with advan