Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Carolina Montenegro‐Venegas"'
Autor:
Armand Blondiaux, Shaobo Jia, Anil Annamneedi, Gürsel Çalışkan, Jana Nebel, Carolina Montenegro-Venegas, Robert C. Wykes, Anna Fejtova, Matthew C. Walker, Oliver Stork, Eckart D. Gundelfinger, Alexander Dityatev, Constanze I. Seidenbecher
Publikováno v:
Neurobiology of Disease, Vol 188, Iss , Pp 106324- (2023)
Epilepsies are multifaceted neurological disorders characterized by abnormal brain activity, e.g. caused by imbalanced synaptic excitation and inhibition. The neural extracellular matrix (ECM) is dynamically modulated by physiological and pathophysio
Externí odkaz:
https://doaj.org/article/58510b50333f47f092cb98e4bfabdd21
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Bassoon is a core scaffold protein of the presynaptic active zone. In brain synapses, the C-terminus of Bassoon is oriented toward the plasma membrane and its N-terminus is oriented toward synaptic vesicles. At the Golgi-apparatus, Bassoon is thought
Externí odkaz:
https://doaj.org/article/293f35936d2f4672a52f113d0883329e
Autor:
Sheila Hoffmann-Conaway, Marisa M Brockmann, Katharina Schneider, Anil Annamneedi, Kazi Atikur Rahman, Christine Bruns, Kathrin Textoris-Taube, Thorsten Trimbuch, Karl-Heinz Smalla, Christian Rosenmund, Eckart D Gundelfinger, Craig Curtis Garner, Carolina Montenegro-Venegas
Publikováno v:
eLife, Vol 9 (2020)
Mechanisms regulating the turnover of synaptic vesicle (SV) proteins are not well understood. They are thought to require poly-ubiquitination and degradation through proteasome, endo-lysosomal or autophagy-related pathways. Bassoon was shown to negat
Externí odkaz:
https://doaj.org/article/a44456381f0e449a8bf5bbd6a6ec0333
Autor:
Daniela Ivanova, Cordelia Imig, Marcial Camacho, Annika Reinhold, Debarpan Guhathakurta, Carolina Montenegro-Venegas, Michael A. Cousin, Eckart D. Gundelfinger, Christian Rosenmund, Benjamin Cooper, Anna Fejtova
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2444-2459.e7 (2020)
Summary: Compensatory endocytosis of released synaptic vesicles (SVs) relies on coordinated signaling at the lipid-protein interface. Here, we address the synaptic function of C-terminal binding protein 1 (CtBP1), a ubiquitous regulator of gene expre
Externí odkaz:
https://doaj.org/article/8e61db36f3074829adbbc96622133068
Autor:
Duxan Arancibia, Matias Lira, Yocelin Cruz, Daniela P. Barrera, Carolina Montenegro-Venegas, Juan A. Godoy, Craig C. Garner, Nibaldo C. Inestrosa, Eckart D. Gundelfinger, Pedro Zamorano, Viviana I. Torres
Publikováno v:
Cells, Vol 8, Iss 11, p 1333 (2019)
Neurons release neurotransmitters at a specialized region of the presynaptic membrane, the active zone (AZ), where a complex meshwork of proteins organizes the release apparatus. The formation of this proteinaceous cytomatrix at the AZ (CAZ) depends
Externí odkaz:
https://doaj.org/article/7ce464c8c8164ed3bf38d51da2923b2b
Autor:
Vesna Lazarevic, Sandra Fieńko, Maria Andres-Alonso, Daniela Anni, Daniela Ivanova, Carolina Montenegro-Venegas, Eckart D. Gundelfinger, Michael A. Cousin, Anna Fejtova
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Despite the central role of amyloid β (Aβ) peptide in the etiopathogenesis of Alzheimer’s disease (AD), its physiological function in healthy brain is still debated. It is well established that elevated levels of Aβ induce synaptic depression an
Externí odkaz:
https://doaj.org/article/e4dc721102d84b10975c005a9b87b42b
Autor:
Franziska Altmüller, Santosh Pothula, Anil Annamneedi, Saeideh Nakhaei-Rad, Carolina Montenegro-Venegas, Eneko Pina-Fernández, Claudia Marini, Monica Santos, Denny Schanze, Dirk Montag, Mohammad R Ahmadian, Oliver Stork, Martin Zenker, Anna Fejtova
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006843 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006684.].
Externí odkaz:
https://doaj.org/article/9f508d33e6cd48faa1a9521ab6557376
Autor:
Franziska Altmüller, Santosh Pothula, Anil Annamneedi, Saeideh Nakhaei-Rad, Carolina Montenegro-Venegas, Eneko Pina-Fernández, Claudia Marini, Monica Santos, Denny Schanze, Dirk Montag, Mohammad R Ahmadian, Oliver Stork, Martin Zenker, Anna Fejtova
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006684 (2017)
Noonan syndrome (NS) is characterized by reduced growth, craniofacial abnormalities, congenital heart defects, and variable cognitive deficits. NS belongs to the RASopathies, genetic conditions linked to mutations in components and regulators of the
Externí odkaz:
https://doaj.org/article/4d79c075e1a8490e85b7c3fa7893b496
Autor:
Markus S Schröder, Anne Stellmacher, Stefano Romorini, Claudia Marini, Carolina Montenegro-Venegas, Wilko D Altrock, Eckart D Gundelfinger, Anna Fejtova
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58814 (2013)
The proper organization of the presynaptic cytomatrix at the active zone is essential for reliable neurotransmitter release from neurons. Despite of the virtual stability of this tightly interconnected proteinaceous network it becomes increasingly cl
Externí odkaz:
https://doaj.org/article/fe98426d33b14ad595998185e71e6e06
Autor:
Daniel R Henríquez, Felipe J Bodaleo, Carolina Montenegro-Venegas, Christian González-Billault
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53123 (2012)
Microtubule-associated protein 1B (MAP1B) is a neuronal protein involved in the stabilization of microtubules both in the axon and somatodendritic compartments. Acute, genetic inactivation of MAP1B leads to delayed axonal outgrowth, most likely due t
Externí odkaz:
https://doaj.org/article/af8454da4e514e0e87b4d15908cfe0b0