Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Carolina Mailhos"'
Autor:
Saulius Zuklys, Georg A. Holländer, Carolina Mailhos, Takashi Yahata, Ken-ichi Hirano, Naoko Negishi, David T. Shima, Katsuto Hozumi, Sonoko Habu, Kiyoshi Ando
Publikováno v:
The Journal of Experimental Medicine
The thymic microenvironment is required for T cell development in vivo. However, in vitro studies have shown that when hematopoietic progenitors acquire Notch signaling via Delta-like (Dll)1 or Dll4, they differentiate into the T cell lineage in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab89cac6269806f9feb7d2847d3be87c
https://doi.org/10.1084/jem.20080134
https://doi.org/10.1084/jem.20080134
Autor:
David T. Shima, Carolina Mailhos
Publikováno v:
Current Opinion in Genetics & Development. 10:536-542
First described in the developing nervous system, Semaphorin III/Neuropilin, Ephrin/Eph, and Delta/Notch signaling relays have now been implicated in the elaboration of the blood vessel network during embryogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94671d7537798cc6f9072e4d5a5cfff4
https://doi.org/10.1016/s0959-437x(00)00124-6
https://doi.org/10.1016/s0959-437x(00)00124-6
Autor:
R P Harbottle, Carolina V. Arancibia-Cárcamo, Roland J. Levinsky, Margreet A. Wolfert, Leonard W. Seymour, Robin R. Ali, Carolina Mailhos, Daniel F P Larkin, A Knight, Adrian J. Thrasher, Stephen L. Hart, Andrew J.T. George, Christine Kinnon, Nicola O’Reilly, Charles Coutelle
Publikováno v:
Human Gene Therapy. 9:575-585
Nonviral vectors consisting of integrin-targeting peptide/DNA (ID) complexes have the potential for widespread application in gene therapy. The transfection efficiency of this vector, however, has been limited by endosomal degradation. We now report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ac8ede040c08cb0a97fd785f4ce680
https://doi.org/10.1089/hum.1998.9.4-575
https://doi.org/10.1089/hum.1998.9.4-575
Publikováno v:
Brain Research. 644:7-12
The extent of programmed cell death (apoptosis) which occurs upon transfer of a neuronal cell line (ND7) to serum-free medium can be greatly increased by addition of retinoic acid (RA) to the medium. Here we show that the degree of apoptosis can also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96cdaecd2da70e99da36d8ecc23ae5d
https://doi.org/10.1016/0006-8993(94)90339-5
https://doi.org/10.1016/0006-8993(94)90339-5
Autor:
Carolina Mailhos, Robert Gurny, Norbert Lange, David T. Shima, Maria Fernanda Zuluaga, Gregory S. Robinson
Publikováno v:
Investigative Ophthalmology & Visual Science, Vol. 48, No 4 (2007) pp. 1767-72
PURPOSE. Photodynamic therapy (PDT) and the administration of compounds acting against vascular endothelial growth factor (anti-VEGF) are approved for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f077a3a7799376945e70020e4d41f3
https://archive-ouverte.unige.ch/unige:14307
https://archive-ouverte.unige.ch/unige:14307
Autor:
Nobuo, Jo, Meihua, Ju, Kazuaki, Nishijima, Gregory S, Robinson, Anthony P, Adamis, David T, Shima, Carolina, Mailhos
Publikováno v:
Molecular vision. 12
The wet form of age-related macular degeneration (AMD) occurs as a consequence of abnormal blood vessel growth from the choroid into the retina. Pathological angiogenesis during tumor growth and ocular disease has been associated with specific exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bb77a05a9cd22fea7f3a37fb22ba5e9
https://pubmed.ncbi.nlm.nih.gov/17110907
https://pubmed.ncbi.nlm.nih.gov/17110907
Autor:
Meihua Ju, Nobuo Jo, Eunice Cheung, Kazuaki Nishijima, David T. Shima, Anthony P. Adamis, Carolina Mailhos, Gregory S. Robinson, John Bradley
Publikováno v:
The American journal of pathology. 168(6)
'Vascular endothelial growth factor-A (VEGF-A) blockade has been recently validated as an effective strategy for the inhibition of new blood vessel growth in cancer and ocular pathologies. However, several studies have also shown that anti-VEGF thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3442a2fca7bb92ee5ce8548818f60a
https://pubmed.ncbi.nlm.nih.gov/25597701
https://pubmed.ncbi.nlm.nih.gov/25597701
Autor:
Yusuke Sotomaru, Carolina Mailhos, David Ish-Horowicz, Daisuke Suzuki, Norikazu Tamaoki, Sonoko Habu, Natsumi Abe, Naoko Negishi, Katsuto Hozumi, Michael J Owen
Publikováno v:
Nature immunology. 5(6)
Notch receptors and their ligands contribute to many developmental systems, but it is not apparent how they function after birth, as their null mutants develop severe defects during embryogenesis. Here we used the Cre-loxP system to delete the Delta-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29077446d60a51ecf46bff3953108d4
https://pubmed.ncbi.nlm.nih.gov/15146182
https://pubmed.ncbi.nlm.nih.gov/15146182
Enhancement of integrin-mediated transfection of haematopoietic cells with a synthetic vector system
Autor:
Aima Uduehi, Adrian J. Thrasher, Hazel Truman, Carolina Mailhos, Stephen L. Hart, Christine Kinnon
Publikováno v:
Biotechnology and applied biochemistry. 38(Pt 3)
The aim of the present study was to develop and assess an integrin-targeted synthetic vector system for the transfection of haematopoietic cell lines and dendritic cells. The vector consists of a cationic liposome, Lipofectin (L), a peptide that both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7171ac2d1121d33e4648ed22532b53
https://pubmed.ncbi.nlm.nih.gov/12812522
https://pubmed.ncbi.nlm.nih.gov/12812522
Autor:
Julian Lewis, David Ish-Horowicz, Ute Modlich, Roy Bicknell, Adrian L. Harris, Carolina Mailhos
Publikováno v:
Scopus-Elsevier
Delta-Notch signalling regulates cell-fate choices in a variety of tissues during development. We report the expression of Delta4 (Dl4) in arterial endothelium during mouse embryogenesis and in the endothelium of tumor blood vessels. The expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fece2019000a6e907cb1cb2979e5f61
https://pubmed.ncbi.nlm.nih.gov/11798067
https://pubmed.ncbi.nlm.nih.gov/11798067