Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Carolina M. Koeller"'
Autor:
Anne C. S. Fernandes, Deivid C. Soares, Roberta F. C. Neves, Carolina M. Koeller, Norton Heise, Camila M. Adade, Susana Frases, José R. Meyer-Fernandes, Elvira M. Saraiva, Thaïs Souto-Padrón
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
In the protozoan pathogen Leishmania, endocytosis, and exocytosis occur mainly in the small area of the flagellar pocket membrane, which makes this parasite an interesting model of strikingly polarized internalization and secretion. Moreover, little
Externí odkaz:
https://doaj.org/article/2e482428e7c54160acc85c2b2dd09cc3
Autor:
Fabricio Montalvão, Danielle Oliveira Nascimento, Marise P. Nunes, Carolina M. Koeller, Alexandre Morrot, Leticia Miranda S. Lery, Paulo M. Bisch, Santuza M. R. Teixeira, Rita Vasconcellos, Leonardo Freire-de-Lima, Marcela F. Lopes, Norton Heise, George A. DosReis, Célio Geraldo Freire-de-Lima
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts. By
Externí odkaz:
https://doaj.org/article/c879b508b68d4d519a59f4bbbf34b088
Publikováno v:
Parasitology
p67 is a type I transmembrane glycoprotein of the terminal lysosome of African trypanosomes. Its biosynthesis involves transport of an initial gp100 ER precursor to the lysosome, followed by cleavage to N-terminal (gp32) and C-terminal (gp42) subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467580dc2e8960b215e8386f00e5df42
http://europepmc.org/articles/PMC8053727
http://europepmc.org/articles/PMC8053727
Publikováno v:
Journal of Biological Chemistry. 295:2227-2238
The transferrin receptor (TfR) of the bloodstream form (BSF) of Trypanosoma brucei is a heterodimer comprising glycosylphosphatidylinositol (GPI)-anchored expression site–associated gene 6 (ESAG6 or E6) and soluble ESAG7. Mature E6 has five N-glyca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15e4d5c48d211bc28627686361c27f6
https://doi.org/10.1074/jbc.ra119.010847
https://doi.org/10.1074/jbc.ra119.010847
Publikováno v:
Molecular Biology of the Cell
Misfolded secretory proteins are retained by endoplasmic reticulum quality control (ERQC) and degraded in the proteasome by ER-associated degradation (ERAD). However, in yeast and mammals, misfolded glycosylphosphatidylinositol (GPI)-anchored protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5116c37d77b3e8ccde4569f74f9d773
http://europepmc.org/articles/PMC6233060
http://europepmc.org/articles/PMC6233060
Autor:
Katia C. Gondim, Peter Bütikofer, Thais Russo-Abrahão, Stephanie Silva-Rito, Amaia Gonzalez-Salgado, Norton Heise, Naira Ligia Lima-Giarola, Michael E. Steinmann, Michele Alves-Bezerra, Iron F. De-Paula, José Roberto Meyer-Fernandes, Carolina M. Koeller, Erwin Sigel, Thaissa Marins-Lucena
Publikováno v:
Russo-Abrahão, Thais; Koeller, Carolina Macedo; Steinmann, Michael Eduard; Silva-Rito, Stephanie; Marins-Lucena, Thaissa; Alves-Bezerra, Michele; Lima-Giarola, Naira Ligia; de-Paula, Iron Francisco; González Salgado, Amaia; Sigel, Erwin; Bütikofer, Peter; Gondim, Katia Calp; Heise, Norton; Meyer-Fernandes, José Roberto (2017). H+-dependent inorganic phosphate uptake in Trypanosoma brucei is influenced by myo-inositol transporter. Journal of bioenergetics and biomembranes, 49(2), pp. 183-194. Springer 10.1007/s10863-017-9695-y
Trypanosoma brucei is an extracellular protozoan parasite that causes human African trypanosomiasis or "sleeping sickness". During the different phases of its life cycle, T. brucei depends on exogenous inorganic phosphate (Pi), but little is known ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23df19cf25bcfb14d2ccabfee78aee2
https://doi.org/10.1007/s10863-017-9695-y
https://doi.org/10.1007/s10863-017-9695-y
Autor:
Anne C S, Fernandes, Deivid C, Soares, Roberta F C, Neves, Carolina M, Koeller, Norton, Heise, Camila M, Adade, Susana, Frases, José R, Meyer-Fernandes, Elvira M, Saraiva, Thaïs, Souto-Padrón
Publikováno v:
Frontiers in Cellular and Infection Microbiology
In the protozoan pathogen Leishmania, endocytosis, and exocytosis occur mainly in the small area of the flagellar pocket membrane, which makes this parasite an interesting model of strikingly polarized internalization and secretion. Moreover, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e4ad5693dfaa7562e6ac2874848173f
https://pubmed.ncbi.nlm.nih.gov/32117812
https://pubmed.ncbi.nlm.nih.gov/32117812
Publikováno v:
J Biol Chem
The transferrin receptor (TfR) of the bloodstream form (BSF) of Trypanosoma brucei is a heterodimer comprising glycosylphosphatidylinositol (GPI)-anchored expression site–associated gene 6 (ESAG6 or E6) and soluble ESAG7. Mature E6 has five N-glyca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d10a240fd5d6fa947387f82dd1c3e0f
https://pubmed.ncbi.nlm.nih.gov/31932305
https://pubmed.ncbi.nlm.nih.gov/31932305
Autor:
James D. Bangs, Carolina M. Koeller
Publikováno v:
Cellular microbiology. 21(4)
Cathepsin L (TbCatL) is an essential lysosomal thiol protease in African trypanosomes. TbCatL is synthesized as two precursor forms (P/X) that are activated to mature form (M) with the removal of the prodomain upon arrival in the lysosome. We examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b2e8541a90916502de306e6899560
https://pubmed.ncbi.nlm.nih.gov/30427109
https://pubmed.ncbi.nlm.nih.gov/30427109
Autor:
Juliana M. Figueiredo, S. Michal Jazwinski, Norton Heise, Carolina M. Koeller, Deivid C. Rodrigues, James C. Jiang, Lucia Mendonça-Previato, Rafael Cardoso Maciel Costa Silva, José O. Previato, Turán P. Ürményi
Publikováno v:
Molecular and Biochemical Parasitology. 182:62-74
In this study, we characterized ceramide synthase (CerS) of the protozoan parasite Trypanosoma cruzi at the molecular and functional levels. TcCerS activity was detected initially in a cell-free system using the microsomal fraction of epimastigote fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1a5ff025a27401b50b4598edb304b6
https://doi.org/10.1016/j.molbiopara.2011.12.006
https://doi.org/10.1016/j.molbiopara.2011.12.006