Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carolina Livi"'
Autor:
Chananat Klomsiri, Edward Grimley, Jon Roussey, Carolina Livi, Casey Wegner, Brandon H. McNaughton, Steve Levers, Vibhu Vivek, Dan Snyder, Doug Summers, Ma Phiengsai
Publikováno v:
Cancer Research. 82:6089-6089
With genomic instability being a hallmark of cancer, heterogeneity within solid tumors is prevalent. Intra-tumoral heterogeneity contributes strongly to clinical outcomes. In fact, heterogeneity is often cited as a driver of therapeutic failure, chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f1905acc7fdeb2dce6938ad97bc1c6
https://doi.org/10.1158/1538-7445.am2022-6089
https://doi.org/10.1158/1538-7445.am2022-6089
Autor:
Edward Grimley, Jon Roussey, Chia Ku, Carolina Livi, Nadia Petlakh-Co, Casey Wegner, Brandon H. McNaughton
Publikováno v:
Cancer Research. 82:5167-5167
Circulating tumor cells (CTCs) have shown incredible promise in clinical and diagnostic applications. CTC-based liquid biopsies can aid in earlier diagnosis, identify the stage of disease, guide therapeutic aggressiveness, and be used to monitor resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc078182de82bdfa45ff7818f1defae
https://doi.org/10.1158/1538-7445.am2022-5167
https://doi.org/10.1158/1538-7445.am2022-5167
Autor:
Robert S. Svatek, Niannian Ji, Neelam Mukherjee, Essel de Leon, Aashish Kabra, Vincent Hurez, Marlo Nicolas, Joel E. Michalek, Martin Javors, Carolina Livi, Z. Dave Sharp, Tyler J. Curiel
Publikováno v:
The Journal of Immunology. 200:177.8-177.8
The mechanistic target of rapamycin (mTOR) integrates environmental inputs to regulate cellular growth and metabolism in tumors. However, mTOR also regulates T cell differentiation and activation, rendering applications of mTOR inhibitors towards tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c22b6206aef9d8091af84d18eb10314
https://doi.org/10.4049/jimmunol.200.supp.177.8
https://doi.org/10.4049/jimmunol.200.supp.177.8
Autor:
Pei Yi Lin, Carolina Livi, Suzanne R Thibodeaux, Margaret E Wierman, Mark Kious, Duane P Jeansonne, Tahiro Shin, Michael J Brumlik, Bin Zhang, Benjamin J Daniel, Tyler J Curiel
Publikováno v:
The Journal of Immunology. 182:40.18-40.18
We tested Treg function in B7-H1-/- (KO) mice. 6-10 wk male (M) or female (F) KO and M or F wildtype (WT) had equal numbers of CD4+CD25hiFoxP3+ T cells (Tregs) with similar CD25 and Foxp3 MFI. CTLA-4 trended lower in F vs M KO. M and F WT and M KO Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e13e5afa43ba4f4bfeacc6147ae94e
https://doi.org/10.4049/jimmunol.182.supp.40.18
https://doi.org/10.4049/jimmunol.182.supp.40.18
Autor:
Shawna Wall, Suzanne R Thibodeaux, Pei Yi Lin, Mark Kious, Duane Jeansonne, Michael J Brumlik, Carolina Livi, Benjamin J Daniel, Tyler J Curiel
Publikováno v:
The Journal of Immunology. 182:41.15-41.15
Treg depletion improves anti-tumor immunity but is unlikely to be curative alone. Denileukin diftitox (DT) depletes Tregs in BL6 mice and prolongs survival 11% at 5 µg/mouse weekly starting 2 weeks after challenge with ID8 ovarian cancer. Weekly hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b562daaade0c361383a540b902c0626
https://doi.org/10.4049/jimmunol.182.supp.41.15
https://doi.org/10.4049/jimmunol.182.supp.41.15
Autor:
Suzanne R Thibodeaux, Tahiro Shin, Benjamin Daniel, Pei Yi Lin, Carolina Livi, Shawna Wall, Michael Brumlik, Mark Kious, Duane Jeansonne, Sara Ludwig, Tyler Curiel
Publikováno v:
The Journal of Immunology. 182:41.62-41.62
CD11b+Gr-1+ cells increase in spleen, ascites and mesenteric lymph nodes in BL6 mice challenged with intraperitoneal OVA-expressing ID8 ovarian carcinoma cells, and boost rather than suppress tumor (OVA)-specific immunity. We studied regulation of CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7502321c71a316161abcdaa0238aa933
https://doi.org/10.4049/jimmunol.182.supp.41.62
https://doi.org/10.4049/jimmunol.182.supp.41.62