Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carolina Gestblom"'
Publikováno v:
British Journal of Cancer
Several unique features of neuroblastoma (NB), including the capacity for spontaneous regression and maturation to benign pathology, suggest that genes that regulate cellular proliferation, survival and differentiation may be involved in directing cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190780afe874a6e0d228c549ea8b9dd5
https://doi.org/10.1038/bjc.1997.203
https://doi.org/10.1038/bjc.1997.203
Publikováno v:
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 4(5)
Multiple endocrine neoplasia type 2B (MEN2B) syndrome is caused by a missense mutation in the RET gene, which replaces Met918 by Thr in the intracellular kinase domain of the protein. This single amino acid substitution transforms the receptor into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701347046ca0cf70f290382fe761a2db
https://pubmed.ncbi.nlm.nih.gov/11779046
https://pubmed.ncbi.nlm.nih.gov/11779046
The tyrosine kinase receptor Ret is expressed in the ureteric bud and is required for normal renal development. Constitutive loss of Ret, its co-receptor gfralpha-1, or the ligand glial cell line-derived neurotrophic factor results in renal agenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08797ea2d49b510f4f5f44b25321815f
https://europepmc.org/articles/PMC1866938/
https://europepmc.org/articles/PMC1866938/
