Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carolina Gándara"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11323 (2021)
DNA lesions that impede fork progression cause replisome stalling and threaten genome stability. Bacillus subtilis RecA, at a lesion-containing gap, interacts with and facilitates DisA pausing at these branched intermediates. Paused DisA suppresses i
Externí odkaz:
https://doaj.org/article/baa81b4f188b4ffa8959324883e7bcf4
Autor:
Rubén Torres, Carolina Gándara, Begoña Carrasco, Ignacio Baquedano, Silvia Ayora, Juan C. Alonso
Publikováno v:
Cells, Vol 10, Iss 6, p 1357 (2021)
The DNA damage checkpoint protein DisA and the branch migration translocase RecG are implicated in the preservation of genome integrity in reviving haploid Bacillus subtilis spores. DisA synthesizes the essential cyclic 3′, 5′-diadenosine monopho
Externí odkaz:
https://doaj.org/article/a0791de762e04d2198c0de5330c4fe41
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11323, p 11323 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11323, p 11323 (2021)
DNA lesions that impede fork progression cause replisome stalling and threaten genome stability. Bacillus subtilis RecA, at a lesion-containing gap, interacts with and facilitates DisA pausing at these branched intermediates. Paused DisA suppresses i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8474a5060d99e24f84ecb048f13330
Autor:
Begoña Carrasco, Carolina Gándara, Silvia Ayora, Rubén Torres, Ignacio Baquedano, Juan C. Alonso
Publikováno v:
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Cells
Cells, Vol 10, Iss 1357, p 1357 (2021)
Volume 10
Issue 6
Universidad de Alicante (UA)
Cells
Cells, Vol 10, Iss 1357, p 1357 (2021)
Volume 10
Issue 6
The DNA damage checkpoint protein DisA and the branch migration translocase RecG are implicated in the preservation of genome integrity in reviving haploid Bacillus subtilis spores. DisA synthesizes the essential cyclic 3′, 5′-diadenosine monopho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae284e7a30021db32382ca2c795ad597
http://hdl.handle.net/10045/116397
http://hdl.handle.net/10045/116397
Autor:
Michelle E. McClements, Hannah Steward, William Atkin, Emily Archer Goode, Carolina Gándara, Valeria Chichagova, Robert E. MacLaren
Publikováno v:
Translational Vision Science & Technology. 11:3
To expand the use of human retinal organoids from induced pluripotent stem cells (iPSCs) as an in vitro model of the retina for assessing gene therapy treatments, it is essential to establish efficient transduction. To date, targeted transduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bff9e8e18ef6218012629d6f6b2669
https://doi.org/10.1167/tvst.11.4.3
https://doi.org/10.1167/tvst.11.4.3
Autor:
Carolina Gándara, Rubén Torres, Daniella Lucena, Peter L. Graumann, Ester Serrano, Juan C. Alonso, Stephan Altenburger
Publikováno v:
DNA Repair. 55:17-30
Bacillus subtilis c-di-AMP synthase DisA and RecA-related RadA/Sms are involved in the repair of DNA damage in exponentially growing cells. We provide genetic evidence that DisA or RadA/Sms is epistatic to the branch migration translocase (BMT) RecG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0b71ba6f69f80c8d3da5184018f0c1
https://doi.org/10.1016/j.dnarep.2017.05.002
https://doi.org/10.1016/j.dnarep.2017.05.002
Autor:
Rubén Torres, Sigal Ben-Yehuda, Begoña Carrasco, Juan C. Alonso, Carolina Gándara, Amit K. Baidya
Publikováno v:
Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Bacillus subtilis diadenylate cyclase DisA converts two ATPs into c-di-AMP, but this activity is suppressed upon interaction with sites of DNA damage. DisA forms a rapid moving focus that pauses upon induction of DNA damage during spore development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e5ee82a5320ee82a8d5546e2ec8d93
https://pubmed.ncbi.nlm.nih.gov/30916351
https://pubmed.ncbi.nlm.nih.gov/30916351
Publikováno v:
Human Gene Therapy Methods
Lentiviral vectors are used in laboratories around the world for in vivo and ex vivo delivery of gene therapies, and increasingly clinical investigation as well as preclinical applications. The third-generation lentiviral vector system has many advan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e97ddf1baefd46f3ca4a7346168dc817
https://pubmed.ncbi.nlm.nih.gov/29212357
https://pubmed.ncbi.nlm.nih.gov/29212357
Publikováno v:
Human Gene Therapy Methods
Lentiviral vectors are increasingly the gene transfer tool of choice for gene or cell therapies, with multiple clinical investigations showing promise for this viral vector in terms of both safety and efficacy. The third-generation vector system is w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f6935f0258e99992e1e7472d8df320
https://pubmed.ncbi.nlm.nih.gov/28817344
https://pubmed.ncbi.nlm.nih.gov/28817344
Autor:
Elena M. Seco, Carolina Gándara, Marina Raguse, Rubén Torres, Silvia Ayora, Juan C. Alonso, Ralf Moeller
Publikováno v:
DNA repair. 59
The mechanisms that allow to circumvent replicative stress, and to resume DNA synthesis are poorly understood in Bacillus subtilis. To study the role of the diadenylate cyclase DisA and branch migration translocase (BMT) RadA/Sms in restarting a stal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37453eddb34e9cdfb579b87829db396d
https://pubmed.ncbi.nlm.nih.gov/28961460
https://pubmed.ncbi.nlm.nih.gov/28961460