Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Carolina Flores-Muñoz"'
1
Akademický článek
Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti
Autor: Ana C. Abbott, Isaac E. García, Felipe Villanelo, Carolina Flores-Muñoz, Ricardo Ceriani, Jaime Maripillán, Joel Novoa-Molina, Cindel Figueroa-Cares, Tomas Pérez-Acle, Juan C. Sáez, Helmuth A. Sánchez, Agustín D. Martínez
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of c
Externí odkaz: https://doaj.org/article/4a2519a57af545099c4f91f689d29670
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2
Akademický článek
Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity
Autor: Francisca García-Rojas, Carolina Flores-Muñoz, Odra Santander, Pamela Solis, Agustín D. Martínez, Álvaro O. Ardiles, Marco Fuenzalida
Publikováno v: Biomolecules, Vol 13, Iss 6, p 887 (2023)
Pannexin-1 (Panx1) hemichannel is a non-selective transmembrane channel that may play important roles in intercellular signaling by allowing the permeation of ions and metabolites, such as ATP. Although recent evidence shows that the Panx1 hemichanne
Externí odkaz: https://doaj.org/article/8ecaa2306d264fb7b9d02fe0f0e00e12
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3
Akademický článek
The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons
Autor: Carolina Flores-Muñoz, Francisca García-Rojas, Miguel A. Pérez, Odra Santander, Elena Mery, Stefany Ordenes, Javiera Illanes-González, Daniela López-Espíndola, Arlek M. González-Jamett, Marco Fuenzalida, Agustín D. Martínez, Álvaro O. Ardiles
Publikováno v: Cells, Vol 11, Iss 22, p 3646 (2022)
Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic neurotransmission, synaptic pl
Externí odkaz: https://doaj.org/article/b2ec816e17904dd487b66dbd7a5d8337
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4
Akademický článek
Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer’s Disease
Autor: Carolina Flores-Muñoz, Bárbara Gómez, Elena Mery, Paula Mujica, Ivana Gajardo, Claudio Córdova, Daniela Lopez-Espíndola, Claudia Durán-Aniotz, Claudio Hetz, Pablo Muñoz, Arlek M. Gonzalez-Jamett, Álvaro O. Ardiles
Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2020)
Synaptic loss induced by soluble oligomeric forms of the amyloid β peptide (sAβos) is one of the earliest events in Alzheimer’s disease (AD) and is thought to be the major cause of the cognitive deficits. These abnormalities rely on defects in sy
Externí odkaz: https://doaj.org/article/ab9d78fa62b742169a3bbb3f43ce7005
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5
Akademický článek
Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling
Autor: Carolina Flores-Muñoz, Jaime Maripillán, Jacqueline Vásquez-Navarrete, Joel Novoa-Molina, Ricardo Ceriani, Helmuth A. Sánchez, Ana C. Abbott, Caroline Weinstein-Oppenheimer, Donald I. Brown, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 3, p 1069 (2021)
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Externí odkaz: https://doaj.org/article/147cbf8208f44eea86a4905123c43b40
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6
Akademický článek
Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice
Autor: Ivana Gajardo, Claudia S. Salazar, Daniela Lopez-Espíndola, Carolina Estay, Carolina Flores-Muñoz, Claudio Elgueta, Arlek M. Gonzalez-Jamett, Agustín D. Martínez, Pablo Muñoz, Álvaro O. Ardiles
Publikováno v: Frontiers in Molecular Neuroscience, Vol 11 (2018)
Long-term potentiation (LTP) and long-term depression (LTD) are two forms of synaptic plasticity that have been considered as the cellular substrate of memory formation. Although LTP has received considerable more attention, recent evidences indicate
Externí odkaz: https://doaj.org/article/bc918fb42ce842238e1240d20e9e6530
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8
Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling
Autor: Donald I. Brown, Jaime Maripillán, Carolina Flores-Muñoz, Joel Novoa-Molina, Ana C Abbott, Caroline Weinstein-Oppenheimer, Ricardo Ceriani, Jacqueline Vásquez-Navarrete, Isaac E. García, Ana M. Cárdenas, Agustín D. Martínez, Helmuth A. Sánchez
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1069, p 1069 (2021)
Volume 22
Issue 3
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e3569e5a1910e5a65363745b1b089
http://europepmc.org/articles/PMC7865282
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9
From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome
Autor: Agustín D. Martínez, Oscar Jara, Amaury Pupo, Felicitas Bosen, Klaus Willecke, Isaac E. García, Carlos Gonzalez, Paula Mujica, Carolina Flores-Muñoz
Publikováno v: The Journal of investigative dermatology. 136(3)
The keratitis-ichthyosis-deafness (KID) syndrome is characterized by corneal, skin, and hearing abnormalities. KID has been linked to heterozygous dominant missense mutations in the GJB2 and GJB6 genes, encoding connexin26 and 30, respectively. In vi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c3da994db051a03d1f67bd7f9ab4a2
https://pubmed.ncbi.nlm.nih.gov/26777423
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10
Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells
Autor: María José Guerra, María José Olivares, Ximena Báez-Matus, Fanny Momboisse, Juan C. Sáez, Agustín D. Martínez, Carolina Flores-Muñoz, Ana M. Cárdenas
Publikováno v: Frontiers in Cellular Neuroscience, Vol 8 (2014)
Frontiers in Cellular Neuroscience
FRONTIERS IN CELLULAR NEUROSCIENCE
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Chromaffin cells of the adrenal gland medulla synthesize and store hormones and peptides, which are released into the blood circulation in response to stress. Among them, adrenaline is critical for the fight-or-flight response. This neurosecretory pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9eeee373314c47a75146f68960b6031
http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00270/full
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