Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carolina F. Ruivo"'
Autor:
Bárbara Adem, Nuno Bastos, Carolina F. Ruivo, Sara Sousa-Alves, Carolina Dias, Patrícia F. Vieira, Inês A. Batista, Bruno Cavadas, Dieter Saur, José C. Machado, Dawen Cai, Sonia A. Melo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the genetically engineered mouse model (
Externí odkaz:
https://doaj.org/article/bc7d9ee1ccd04333abccf2b19c10a836
Autor:
Lamiaa El-Shennawy, Andrew D. Hoffmann, Nurmaa Khund Dashzeveg, Kathleen M. McAndrews, Paul J. Mehl, Daphne Cornish, Zihao Yu, Valerie L. Tokars, Vlad Nicolaescu, Anastasia Tomatsidou, Chengsheng Mao, Christopher J. Felicelli, Chia-Feng Tsai, Carolina Ostiguin, Yuzhi Jia, Lin Li, Kevin Furlong, Jan Wysocki, Xin Luo, Carolina F. Ruivo, Daniel Batlle, Thomas J. Hope, Yang Shen, Young Kwang Chae, Hui Zhang, Valerie S. LeBleu, Tujin Shi, Suchitra Swaminathan, Yuan Luo, Dominique Missiakas, Glenn C. Randall, Alexis R. Demonbreun, Michael G. Ison, Raghu Kalluri, Deyu Fang, Huiping Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
El-Shennawy et al. report that ACE2+ circulating extracellular vesicles (evACE2) are associated with COVID-19 severity and that evACE2 inhibits the infection of SARS-CoV-2 variants of concern at a higher efficacy than soluble ACE2.
Externí odkaz:
https://doaj.org/article/271c6c97f77947d1a54cafa9338a135a
Autor:
Ivan Stojanović, Carolina F. Ruivo, Thomas J. G. van der Velden, Richard B. M. Schasfoort, Leon W. M. M. Terstappen
Publikováno v:
Biosensors, Vol 9, Iss 2, p 70 (2019)
Rapid multiplex cell surface marker analysis can expedite investigations in which large number of antigens need to be analyzed. Simultaneous analysis of multiple surface antigens at the same level of sensitivity is however limited in the current gold
Externí odkaz:
https://doaj.org/article/be01e67222ad44a5ae442c8418336391
Autor:
Carolina F Ruivo, Nuno Bastos, Barbara Adem, Ines Batista, Cecilia Duraes, Carlos A Melo, Stephanie A Castaldo, Francisco Campos‐Laborie, Pedro Moutinho-Ribeiro, Barbara Morão, Ana Costa-Pinto, Soraia Silva, Hugo Osorio, Sergio Ciordia, Jose Luis Costa, David Goodrich, Bruno Cavadas, Luisa Pereira, Tony Kouzarides, Guilherme Macedo, Rui Maio, Fatima Carneiro, Marília Cravo, Raghu Kalluri, Jose Carlos Machado, Sonia A Melo
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0310b4f559857f08a9f43bab5d8a50c3
https://lirias.kuleuven.be/handle/20.500.12942/707762
https://lirias.kuleuven.be/handle/20.500.12942/707762
Autor:
José Mauro Granjeiro, Maria José Oliveira, Sonia A. Melo, Luís Augusto Rocha, Ana Lúcia Roselino Ribeiro, Maria Helena Fernandes, Carolina F. Ruivo, Patricia Cardoso, Wanderson de Souza, Nuno Bastos, Sara G. Piperni
BackgroundThe inflammatory response to titanium implant-derived wear particles is considered as the hallmark of periprosthetic osteolysis, an event that cause pain, reduce patient motility, ultimately leading to the need of a revision surgery. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36541175232cf5b92f2afdc537a98731
https://doi.org/10.21203/rs.3.rs-657724/v1
https://doi.org/10.21203/rs.3.rs-657724/v1
Autor:
Inês A. Batista, Susana Silva, Armando Peixoto, Carolina F. Ruivo, Guilherme Macedo, Fátima Carneiro, Pedro Costa-Moreira, Rui Morais, Soraia Melo, Miguel Silva, Bárbara Adem, Rosa Coelho, Joanne Lopes, Filipe Vilas-Boas, Susana Lopes, Pedro Moutinho-Ribeiro, H. Barroca, Cecília Durães
Publikováno v:
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 54(7)
BACKGROUND AND AIMS Pancreatic ductal adenocarcinoma (PDAC) diagnosis can be difficult in a chronic pancreatitis (CP) background, especially in its mass forming presentation. We aimed to assess the accuracy of glypican-1-positive circulating exosomes
Autor:
Carolina F. Ruivo, Sonia A. Melo, Bárbara Adem, Dieter Saur, Barbara Seidler, Nuno Bastos, Dawen Cai
Exosomes are described as central players in a myriad of biological processes. However, the available methodologies to study their function in complex biological systems in vivo are still very limited. The biodistribution of endogenously produced exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4d4bd89d4d6a09754205c3e4f213b1
https://doi.org/10.1101/2021.03.10.434407
https://doi.org/10.1101/2021.03.10.434407
Autor:
Marília Cravo, Guilherme Macedo, Cecília Durães, Raghu Kalluri, Carolina F. Ruivo, José Carlos Machado, Bárbara Adem, Inês A. Batista, Carlos A. Melo, Nuno Bastos, Barbara Mourão, Sonia Melo, Francisco J. Campos‐Laborie, Pedro Moutinho-Ribeiro, Fátima Carneiro, Tony Kouzarides
Publikováno v:
Cancer Research. 81:2010-2010
Intra-tumor heterogeneity represents a major challenge for cancer treatment. Resistance to therapy and tumorigenic ability varies greatly between distinct subpopulations of cancer cells. Intercellular communication is critical to establish a cooperat
Autor:
Raghu Kalluri, J. Jack Lee, Sonia A. Melo, Valerie S. LeBleu, Sushrut Kamerkar, Hikaru Sugimoto, Sujuan Yang, Carolina F. Ruivo
Publikováno v:
Nature. 546:498-503
The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. Exosomes are extracellular vesicles generated by all cells, and are naturally present in the blood. Here we show that enhanced reten
Autor:
Sonia A. Melo, Carolina F. Ruivo
Publikováno v:
Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs ISBN: 9783319715520
Exosomes are a specific population of extracellular vesicles (EVs) that originate from an endocytic process. Virtually every cell type secretes exosomes and their size ranges from 40 to 150 nm. Exosomes are surrounded by a lipid bilayer and contain f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a080b56747ef32b66992c17b4579de3a
https://doi.org/10.1007/978-3-319-71553-7_3
https://doi.org/10.1007/978-3-319-71553-7_3