Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carolina Eliscovich"'
Autor:
Rajiv Pathak, Carolina Eliscovich, Ignacio Mena, Anastasija Cupic, Magdalena Rutkowska, Kartik Chandran, Rohit K. Jangra, Adolfo García-Sastre, Robert H. Singer, Ganjam V. Kalpana
Publikováno v:
Viruses, Vol 16, Iss 2, p 262 (2024)
SARS-CoV-2 infection remains a global burden. Despite intensive research, the mechanism and dynamics of early viral replication are not completely understood, such as the kinetics of the formation of genomic RNA (gRNA), sub-genomic RNA (sgRNA), and r
Externí odkaz:
https://doaj.org/article/5eb3557e958b465e866222b03412dab6
Autor:
Jeetayu Biswas, Vivek L. Patel, Varun Bhaskar, Jeffrey A. Chao, Robert H. Singer, Carolina Eliscovich
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of ZBP1 and IMP2.
Externí odkaz:
https://doaj.org/article/85ff9493a0c0443292b6df3d1c010479
Autor:
Rajiv Pathak, Carolina Eliscovich, Ignacio Mena, Updesh Dixit, Adolfo García-Sastre, Robert H Singer, Ganjam V. Kalpana
Publikováno v:
bioRxiv
SARS-CoV-2 infection has caused a major global burden. Despite intensive research, the mechanism and dynamics of early viral replication are not completely understood including the kinetics of formation of plus stranded genomic and subgenomic RNAs (g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec9897cc75b5ff38dc1e12d1ca32456
https://pubmed.ncbi.nlm.nih.gov/36561180
https://pubmed.ncbi.nlm.nih.gov/36561180
Autor:
Ralf-Peter Jansen, Orit Hermesh, Joyita Mukherjee, Mirita Franz-Wachtel, Carolina Eliscovich, Nicolas C. Nalpas, Boris Macek
Publikováno v:
Proceedings of the National Academy of Sciences. 116:12863-12872
The molecular function and fate of mRNAs are controlled by RNA-binding proteins (RBPs). However, identification of the interacting proteome of a specific mRNA in vivo is still very challenging. Based on the widely-used RNA tagging with MS2 aptamers f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac08e5a3b3bd6ffbb4cbb5adc7d5703
https://doi.org/10.1073/pnas.1820737116
https://doi.org/10.1073/pnas.1820737116
Autor:
Sulagna Das, Leti Nunez, Robert H. Singer, Carolina Eliscovich, Jeetayu Biswas, Young J. Yoon
Publikováno v:
Cold Spring Harb Symp Quant Biol
The fate of an RNA, from its localization, translation, and ultimate decay, is dictated by interactions with RNA binding proteins (RBPs). β-actin mRNA has functioned as the classic example of RNA localization in eukaryotic cells. Studies of β-actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0999f82ef3ee8baf1fc7470cb90414
https://doi.org/10.1101/sqb.2019.84.039396
https://doi.org/10.1101/sqb.2019.84.039396
Autor:
Shuxian Dong, Aurora Scrivo, Carolina Eliscovich, Jose Javier Bravo-Cordero, Ana Maria Cuervo, C. Aguirre-Hernandez, Esperanza Arias
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Autophagy malfunctioning occurs in multiple human disorders, making attractive the idea of chemically modulating it with therapeutic purposes. However, for many types of autophagy, a clear understanding of tissue-specific differences in their activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcdb1a0caf3ef5d0190f78bbe162679
https://doi.org/10.1038/s41467-019-14164-4
https://doi.org/10.1038/s41467-019-14164-4
Autor:
Carolina Eliscovich, Ales Cvekl
Publikováno v:
Exp Eye Res
Cellular differentiation is marked by temporally and spatially regulated gene expression. The ocular lens is one of the most powerful mammalian model system since it is composed from only two cell subtypes, called lens epithelial and fiber cells. Len
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f399a40ca7360560dd4d73de69a84f90
https://doi.org/10.1016/j.exer.2021.108564
https://doi.org/10.1016/j.exer.2021.108564
Autor:
Robert H. Singer, Carolina Eliscovich
Publikováno v:
Current Opinion in Cell Biology. 45:38-46
Regulation of gene expression is key determinant to cell structure and function. RNA localization, where specific mRNAs are transported to subcellular regions and then translated, is highly conserved in eukaryotes ranging from yeast to extremely spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05d87bda0b7337fb6e1cc49e2ad116d
https://doi.org/10.1016/j.ceb.2017.02.008
https://doi.org/10.1016/j.ceb.2017.02.008
Autor:
Vivek Patel, Robert H. Singer, Jeffrey A. Chao, Carolina Eliscovich, Varun Bhaskar, Jeetayu Biswas
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The IGF2 mRNA-binding proteins (ZBP1/IMP1, IMP2, IMP3) are highly conserved post-transcriptional regulators of RNA stability, localization and translation. They play important roles in cell migration, neural development, metabolism and cancer cell su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6884f9d59e752297bf17da34de62290c
http://europepmc.org/articles/PMC6768852
http://europepmc.org/articles/PMC6768852